Page 1 | Search Results | Journal of Experimental Medicine

1-20 of 44

Sort by

Sort Order Select

Journal Articles

Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2

In Special Collection:

Neuroimmunology and Neurodegeneration 2024

Chen Yu, Eleonora M. Lad, Rose Mathew, Nobuhiko Shiraki, Sejiro Littleton, Yun Chen, Jinchao Hou, Kai Schlepckow, Simone Degan, Lindsey Chew, Joshua Amason, Joan Kalnitsky, Catherine Bowes Rickman, Alan D. Proia, Marco Colonna, Christian Haass, Daniel R. Saban

J Exp Med (2024) 221 (3): e20231011.

https://doi.org/10.1084/jem.20231011

Published: 30 January 2024

View article titled, Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2

Includes: Supplementary data

Journal Articles

Inositol phosphatase INPP4B sustains ILC1s and intratumoral NK cells through an AKT-driven pathway

In Special Collection:

JEM Cancer Collection 2024 , Cancer Immunotherapy Update 2024 , Innate Lymphoid Cells 2024

Vincent Peng, Tihana Trsan, Raki Sudan, Bishan Bhattarai, Victor S. Cortez, Martina Molgora, Jean Vacher, Marco Colonna

J Exp Med (2024) 221 (3): e20230124.

https://doi.org/10.1084/jem.20230124

Published: 10 January 2024

View article titled, Inositol phosphatase INPP4B sustains ILC1s and intratumoral NK cells through an AKT-driven pathway

Includes: Supplementary data

Journal Articles

Microglia in Alzheimer's disease at single-cell level. Are there common patterns in humans and mice?

In Special Collection:

Neuroscience Collection 2021

Yun Chen, Marco Colonna

J Exp Med (2021) 218 (9): e20202717.

https://doi.org/10.1084/jem.20202717

Published: 22 July 2021

View article titled, Microglia in Alzheimer's disease at single-cell level. Are there common patterns in humans and mice?

Journal Articles

Activated microglia mitigate Aβ-associated tau seeding and spreading

In Special Collection:

2021: The Year in Experimental Medicine , Neuroscience Collection 2021

Maud Gratuze, Yun Chen, Samira Parhizkar, Nimansha Jain, Michael R. Strickland, Javier Remolina Serrano, Marco Colonna, Jason D. Ulrich, David M. Holtzman

J Exp Med (2021) 218 (8): e20210542.

https://doi.org/10.1084/jem.20210542

Published: 08 June 2021

View article titled, Activated microglia mitigate Aβ-associated tau seeding and spreading

Journal Articles

JEM career launchpad

Anna Bigas, Ivan Zanoni, Matthew R. Hepworth, Stephanie C. Eisenbarth, Seth Lucian Masters, Jonathan Kipnis, Carola G. Vinuesa, Kim L. Good-Jacobson, Stuart G. Tangye, Sayuri Yamazaki, Claire Hivroz, Elia Tait Wojno, Ziv Shulman, Marco Colonna

J Exp Med (2021) 218 (2): e20202509.

https://doi.org/10.1084/jem.20202509

Published: 19 January 2021

View article titled, JEM career launchpad

Journal Articles

Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease model

In Special Collection:

Neurodegenerative Diseases: Biology & Therapeutics

Shoutang Wang, Meer Mustafa, Carla M. Yuede, Santiago Viveros Salazar, Philip Kong, Hua Long, Michael Ward, Omer Siddiqui, Robert Paul, Susan Gilfillan, Adiljan Ibrahim, Hervé Rhinn, Ilaria Tassi, Arnon Rosenthal, Tina Schwabe, Marco Colonna

J Exp Med (2020) 217 (9): e20200785.

https://doi.org/10.1084/jem.20200785

Published: 24 June 2020

View article titled, Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease model

Journal Articles

Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2

J Exp Med (2019) 217 (3): e20190489.

https://doi.org/10.1084/jem.20190489

Published: 26 December 2019

View article titled, Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2

Journal Articles

ILC2s are the predominant source of intestinal ILC-derived IL-10

In Special Collection:

Tissue Immune Responses: Immune Cells and Mechanisms

Jennifer K. Bando, Susan Gilfillan, Blanda Di Luccia, José L. Fachi, Cristiane Sécca, Marina Cella, Marco Colonna

J Exp Med (2019) 217 (2): e20191520.

https://doi.org/10.1084/jem.20191520

Published: 07 November 2019

View article titled, ILC2s are the predominant source of intestinal ILC-derived IL-10

Includes: Supplementary data

Journal Articles

ILC3s integrate glycolysis and mitochondrial production of reactive oxygen species to fulfill activation demands

Blanda Di Luccia, Susan Gilfillan, Marina Cella, Marco Colonna, Stanley Ching-Cheng Huang

J Exp Med (2019) 216 (10): 2231–2241.

https://doi.org/10.1084/jem.20180549

Published: 11 July 2019

View article titled, ILC3s integrate glycolysis and mitochondrial production of reactive oxygen species to fulfill activation demands

Includes: Supplementary data

Journal Articles

Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors

Liangyue Qian, Sandra Bajana, Constantin Georgescu, Vincent Peng, Hong-Cheng Wang, Indra Adrianto, Marco Colonna, Jose Alberola-Ila, Jonathan D. Wren, Xiao-Hong Sun

J Exp Med (2019) 216 (4): 884–899.

https://doi.org/10.1084/jem.20182100

Published: 21 March 2019

View article titled, Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors

Includes: Supplementary data

Journal Articles

ApoE facilitates the microglial response to amyloid plaque pathology

In Special Collection:

Advances in Neurodegenerative Disease Research and Therapy , Neuroscience 2018

Jason D. Ulrich, Tyler K. Ulland, Thomas E. Mahan, Sofie Nyström, K. Peter Nilsson, Wilbur M. Song, Yingyue Zhou, Mariska Reinartz, Seulah Choi, Hong Jiang, Floy R. Stewart, Elise Anderson, Yaming Wang, Marco Colonna, David M. Holtzman

J Exp Med (2018) 215 (4): 1047–1058.

https://doi.org/10.1084/jem.20171265

Published: 26 February 2018

View article titled, ApoE facilitates the microglial response to amyloid plaque pathology

Includes: Supplementary data

Journal Articles

Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism

In Special Collection:

2018: The Year in Experimental Medicine , Advances in Neurodegenerative Disease Research and Therapy , Cytokines 2018 , Myeloid Cells 2019 , Neuroscience 2018

Wilbur M. Song, Satoru Joshita, Yingyue Zhou, Tyler K. Ulland, Susan Gilfillan, Marco Colonna

J Exp Med (2018) 215 (3): 745–760.

https://doi.org/10.1084/jem.20171529

Published: 10 January 2018

View article titled, Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism

Includes: Supplementary data

Journal Articles

MHC II⁺ resident peritoneal and pleural macrophages rely on IRF4 for development from circulating monocytes

Ki-Wook Kim, Jesse W. Williams, Ya-Ting Wang, Stoyan Ivanov, Susan Gilfillan, Marco Colonna, Herbert W. Virgin, Emmanuel L. Gautier, Gwendalyn J. Randolph

J Exp Med (2016) 213 (10): 1951–1959.

https://doi.org/10.1084/jem.20160486

Published: 22 August 2016

View article titled, MHC II+ resident peritoneal and pleural macrophages rely on IRF4 for development from circulating monocytes

Includes: Supplementary data

Journal Articles

Inflammatory monocytes and NK cells play a crucial role in DNAM-1–dependent control of cytomegalovirus infection

Tihana Lenac Rovis, Paola Kucan Brlic, Noa Kaynan, Vanda Juranic Lisnic, Ilija Brizic, Stefan Jordan, Adriana Tomic, Daria Kvestak, Marina Babic, Pinchas Tsukerman, Marco Colonna, Ulrich Koszinowski, Martin Messerle, Ofer Mandelboim, Astrid Krmpotic, Stipan Jonjic

J Exp Med (2016) 213 (9): 1835–1850.

https://doi.org/10.1084/jem.20151899

Published: 08 August 2016

View article titled, Inflammatory monocytes and NK cells play a crucial role in DNAM-1–dependent control of cytomegalovirus infection

Includes: Supplementary data

Journal Articles

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

Yaming Wang, Tyler K. Ulland, Jason D. Ulrich, Wilbur Song, John A. Tzaferis, Justin T. Hole, Peng Yuan, Thomas E. Mahan, Yang Shi, Susan Gilfillan, Marina Cella, Jaime Grutzendler, Ronald B. DeMattos, John R. Cirrito, David M. Holtzman, Marco Colonna

J Exp Med (2016) 213 (5): 667–675.

https://doi.org/10.1084/jem.20151948

Published: 18 April 2016

View article titled, TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

Journal Articles

DNAM-1 controls NK cell activation via an ITT-like motif

Zhanguang Zhang, Ning Wu, Yan Lu, Dominique Davidson, Marco Colonna, André Veillette

J Exp Med (2015) 212 (12): 2165–2182.

https://doi.org/10.1084/jem.20150792

Published: 09 November 2015

View article titled, DNAM-1 controls NK cell activation via an ITT-like motif

Journal Articles

Unique and redundant functions of NKp46⁺ ILC3s in models of intestinal inflammation

Christina Song, Jacob S. Lee, Susan Gilfillan, Michelle L. Robinette, Rodney D. Newberry, Thaddeus S. Stappenbeck, Matthias Mack, Marina Cella, Marco Colonna

J Exp Med (2015) 212 (11): 1869–1882.

https://doi.org/10.1084/jem.20151403

Published: 12 October 2015

View article titled, Unique and redundant functions of NKp46+ ILC3s in models of intestinal inflammation

Includes: Supplementary data

Journal Articles

TREM-2 promotes macrophage survival and lung disease after respiratory viral infection

Kangyun Wu, Derek E. Byers, Xiaohua Jin, Eugene Agapov, Jennifer Alexander-Brett, Anand C. Patel, Marina Cella, Susan Gilfilan, Marco Colonna, Daniel L. Kober, Tom J. Brett, Michael J. Holtzman

J Exp Med (2015) 212 (5): 681–697.

https://doi.org/10.1084/jem.20141732

Published: 20 April 2015

View article titled, TREM-2 promotes macrophage survival and lung disease after respiratory viral infection

Includes: Supplementary data

Journal Articles

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

Sarah L. Rowland, Jeffrey M. Riggs, Susan Gilfillan, Mattia Bugatti, William Vermi, Roland Kolbeck, Emil R. Unanue, Miguel A. Sanjuan, Marco Colonna

J Exp Med (2014) 211 (10): 1977–1991.

https://doi.org/10.1084/jem.20132620

Published: 01 September 2014

View article titled, Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

Journal Articles

CRTAM controls residency of gut CD4⁺CD8⁺ T cells in the steady state and maintenance of gut CD4⁺ Th17 during parasitic infection

Victor S. Cortez, Luisa Cervantes-Barragan, Christina Song, Susan Gilfillan, Keely G. McDonald, Roxane Tussiwand, Brian T. Edelson, Yoshinori Murakami, Kenneth M. Murphy, Rodney D. Newberry, L. David Sibley, Marco Colonna

J Exp Med (2014) 211 (4): 623–633.

https://doi.org/10.1084/jem.20130904

Published: 31 March 2014

View article titled, CRTAM controls residency of gut CD4+CD8+ T cells in the steady state and maintenance of gut CD4+ Th17 during parasitic infection

Includes: Supplementary data

NARROW

Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2

Inositol phosphatase INPP4B sustains ILC1s and intratumoral NK cells through an AKT-driven pathway

Microglia in Alzheimer's disease at single-cell level. Are there common patterns in humans and mice?

Activated microglia mitigate Aβ-associated tau seeding and spreading

JEM career launchpad

Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease model

Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2

ILC2s are the predominant source of intestinal ILC-derived IL-10

ILC3s integrate glycolysis and mitochondrial production of reactive oxygen species to fulfill activation demands

Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors

ApoE facilitates the microglial response to amyloid plaque pathology

Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism

MHC II⁺ resident peritoneal and pleural macrophages rely on IRF4 for development from circulating monocytes

Inflammatory monocytes and NK cells play a crucial role in DNAM-1–dependent control of cytomegalovirus infection

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

DNAM-1 controls NK cell activation via an ITT-like motif

Unique and redundant functions of NKp46⁺ ILC3s in models of intestinal inflammation

TREM-2 promotes macrophage survival and lung disease after respiratory viral infection

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

CRTAM controls residency of gut CD4⁺CD8⁺ T cells in the steady state and maintenance of gut CD4⁺ Th17 during parasitic infection

Email alerts

Email alerts

This Feature Is Available To Subscribers Only