Related Articles from Rockefeller University Press
NF-κB inhibition in keratinocytes causes RIPK1-mediated necroptosis and skin inflammationSnehlata Kumari ... Manolis Pasparakis | Life Sci. Alliance
TNFR1 was found to cause skin inflammation in mice with epidermal keratinocyte-specific ablation of IKK2 or of both the NF-kB subunits RelA and cRel by triggering RIPK1-dependent, RIPK3-MLKL–mediated necroptosis of keratinocytes.
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophagesSamantha B Kemp ... Marina Pasca di Magliano | Life Sci. Alliance
This study uses biomaterial scaffolds to identify a macrophage gene signature defined by high expression of C1qa, C1qb, and Trem2 that is elevated systemically in mouse and human pancreatic cancer.
DGCR8 deficiency impairs macrophage growth and unleashes the interferon response to mycobacteriaBarbara Killy ... Roland Lang | Life Sci. Alliance
Lack of miRNA biosynthesis in DGCR8-deficient macrophages did not block macrophage differentiation but caused overshooting type I IFN responses to mycobacterial glycolipids.