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Neuroimmunology and Neurodegeneration 2024

This collection covers retinal degeneration, meningeal lymphatics, anti-amyloid immunotherapy, tauopathy, and the role of microglia in the pathogenesis of neuroinflammation.

We hope you enjoy reading this collection, and we invite you to follow JEM on X/Twitter (@JExpMed). To learn more about JEM or to submit your research, please visit our Instructions for Authors or reach out to our team of editors. Sign up to receive future special collections here.

Image © 2024 Brenner et al.

Special Collection Image
Perspective
Immune drivers of pain
Aakanksha Jain; Sara Hakim; Clifford J. Woolf
https://doi.org/10.1084/jem.20221687
Brief Definitive Report
TBK1 p.E696K mutation causes ALS in mice
David Brenner; Kirsten Sieverding; Jahnavi Srinidhi; Susanne Zellner; Christopher Secker; Rüstem Yilmaz; Julia Dyckow; Shady Amr; Anna Ponomarenko; Esra Tunaboylu; Yasmin Douahem; Joana S. Schlag; Lucía Rodríguez Martínez; Georg Kislinger; Cornelia Niemann; Karsten Nalbach; Wolfgang P. Ruf; Jonathan Uhl; Johanna Hollenbeck; Lucas Schirmer; Alberto Catanese; Christian S. Lobsiger; Karin M. Danzer; Deniz Yilmazer-Hanke; Christian Münch; Philipp Koch; Axel Freischmidt; Martina Fetting; Christian Behrends; Rosanna Parlato; Jochen H. Weishaupt
https://doi.org/10.1084/jem.20221190
Article
Neuroprotection by VEGF-C prophylaxis on stroke
Ligia Simoes Braga Boisserand; Luiz Henrique Geraldo; Jean Bouchart; Marie-Renee El Kamouh; Seyoung Lee; Basavaraju G. Sanganahalli; Myriam Spajer; Shenqi Zhang; Sungwoon Lee; Maxime Parent; Yuechuan Xue; Mario Skarica; Xiangyun Yin; Justine Guegan; Kevin Boyé; Felipe Saceanu Leser; Laurent Jacob; Mathilde Poulet; Mingfeng Li; Xiaodan Liu; Sofia E. Velazquez; Ruchith Singhabahu; Mark E. Robinson; Michael H. Askenase; Artem Osherov; Nenad Sestan; Jiangbing Zhou; Kari Alitalo; Eric Song; Anne Eichmann; Lauren H. Sansing; Helene Benveniste; Fahmeed Hyder; Jean-Leon Thomas
https://doi.org/10.1084/jem.20221983
Article
Role of Ch25h in tau-mediated neurodegeneration
Danira Toral-Rios; Justin M. Long; Jason D. Ulrich; Jinsheng Yu; Michael R. Strickland; Xianlin Han; David M. Holtzman; Anil G. Cashikar; Steven M. Paul
https://doi.org/10.1084/jem.20232000
Article
Neuroprotective microglia in retinal degeneration
Chen Yu; Eleonora M. Lad; Rose Mathew; Nobuhiko Shiraki; Sejiro Littleton; Yun Chen; Jinchao Hou; Kai Schlepckow; Simone Degan; Lindsey Chew; Joshua Amason; Joan Kalnitsky; Catherine Bowes Rickman; Alan D. Proia; Marco Colonna; Christian Haass; Daniel R. Saban
https://doi.org/10.1084/jem.20231011
Article
Aducanumab induces microglial-immune alterations
Mika P. Cadiz; Katelin A. Gibson; Kennedi T. Todd; David G. Nascari; Nashali Massa; Meredith T. Lilley; Kimberly C. Olney; Md Mamun Al-Amin; Hong Jiang; David M. Holtzman; John D. Fryer
https://doi.org/10.1084/jem.20231363
Article
ARL6IP1 is therapeutic target for HSP disease
Jung Hwa Lim; Hyun Mi Kang; Dae Hun Kim; Bohyeon Jeong; Da Yong Lee; Jae-Ran Lee; Jeong Yeob Baek; Hyun-Soo Cho; Mi-Young Son; Dae Soo Kim; Nam-Soon Kim; Cho-Rok Jung
https://doi.org/10.1084/jem.20230367

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