Skip to Main Content



  • Cover Image

    Cover Image

    issue cover

    Morphological changes after treatment with IgM anti-Fas mAb. To investigate the function of aberrant Fas that lacked whole death-signaling domain, we constructed the retroviral vector LdelSN containing the truncated Fas cDNA and transferred it into Jurkat cells. The top panels indicate the natural form of the retroviral vector LXSN-transduced Jurkat cell clone (left) and the LdelSN-transduced Jurkat cell clone (right). After a 16-h culture with the mAb, the characteristic features of apoptosis, including reduction of cell size, condensation and aggregation of nuclear chromatin, and nuclear fractionation, were observed in the LXSN-transduced Jurkat cell clone (bottom left); no morphological change was observed in the LdelSN-transduced Jurkat cell clone (bottom right). See related article in this issue by Maeda et al., pp. 1063–1071.

  • PDF Icon PDF LinkTable of Contents
  • PDF Icon PDF LinkEditorial Board
ISSN 0022-1007
EISSN 1540-9538
In this Issue



Brief Definitive Report

Close Modal
This Feature Is Available To Subscribers Only

Sign In or Create an Account

Close Modal
Close Modal