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Experimental encephalomyelitis at age 90, still relevant and elucidating how viruses trigger disease

In Special Collection:

Autoimmunity: From Novel Mechanisms to Treatments , Neuroscience Collection 2023 , Neuroimmunology and Neurodegeneration 2023

Lawrence Steinman, Roberto Patarca, William Haseltine

J Exp Med (2023) 220 (2): e20221322.

https://doi.org/10.1084/jem.20221322

Published: 18 January 2023

View article titled, Experimental encephalomyelitis at age 90, still relevant and elucidating how viruses trigger disease

Includes: Supplementary data

Journal Articles

Correction: Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity

Shannon E. Dunn, Shalina S. Ousman, Raymond A. Sobel, Luis Zuniga, Sergio E. Baranzini, Sawsan Youssef, Andrea Crowell, John Loh, Jorge Oksenberg, Lawrence Steinman

J Exp Med (2018) 215 (6): 1765.

https://doi.org/10.1084/jem.2006183905142018c

Published: 17 May 2018

View article titled, Correction: Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity

Journal Articles

Mechanisms of action of therapeutic amyloidogenic hexapeptides in amelioration of inflammatory brain disease

Michael P. Kurnellas, Jill M. Schartner, C. Garrison Fathman, Ann Jagger, Lawrence Steinman, Jonathan B. Rothbard

J Exp Med (2014) 211 (9): 1847–1856.

https://doi.org/10.1084/jem.20140107

Published: 29 July 2014

View article titled, Mechanisms of action of therapeutic amyloidogenic hexapeptides in amelioration of inflammatory brain disease

Includes: Supplementary data

Journal Articles

Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation

Zhaoqing Ding, Vidhu Mathur, Peggy P. Ho, Michelle L. James, Kurt M. Lucin, Aileen Hoehne, Haitham Alabsi, Sanjiv S. Gambhir, Lawrence Steinman, Jian Luo, Tony Wyss-Coray

J Exp Med (2014) 211 (2): 189–198.

https://doi.org/10.1084/jem.20120696

Published: 03 February 2014

View article titled, Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation

Journal Articles

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

J Exp Med (2012) 209 (7): 1325–1334.

https://doi.org/10.1084/jem.20101974

Published: 25 June 2012

View article titled, Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

Includes: Supplementary data

Journal Articles

Peroxisome proliferator–activated receptor δ limits the expansion of pathogenic Th cells during central nervous system autoimmunity

Shannon E. Dunn, Roopa Bhat, Daniel S. Straus, Raymond A. Sobel, Robert Axtell, Amanda Johnson, Kim Nguyen, Lata Mukundan, Marina Moshkova, Jason C. Dugas, Ajay Chawla, Lawrence Steinman

J Exp Med (2010) 207 (8): 1599–1608.

https://doi.org/10.1084/jem.20091663

Published: 12 July 2010

View article titled, Peroxisome proliferator–activated receptor δ limits the expansion of pathogenic Th cells during central nervous system autoimmunity

Includes: Supplementary data

Journal Articles

A rush to judgment on Th17

Lawrence Steinman

J Exp Med (2008) 205 (7): 1517–1522.

https://doi.org/10.1084/jem.20072066

Published: 30 June 2008

View article titled, A rush to judgment on Th17

Journal Articles

Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity

Shannon E. Dunn, Shalina S. Ousman, Raymond A. Sobel, Luis Zuniga, Sergio E. Baranzini, Sawsan Youssef, Andrea Crowell, John Loh, Jorge Oksenberg, Lawrence Steinman

J Exp Med (2007) 204 (3): 693.

https://doi.org/10.1084/jem.20061839020807c

Published: 19 March 2007

View article titled, Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity

Journal Articles

Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity

Shannon E. Dunn, Shalina S. Ousman, Raymond A. Sobel, Luis Zuniga, Sergio E. Baranzini, Sawsan Youssef, Andrea Crowell, John Loh, Jorge Oksenberg, Lawrence Steinman

J Exp Med (2007) 204 (2): 321–330.

https://doi.org/10.1084/jem.20061839

Published: 29 January 2007

View article titled, Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity

Includes: Supplementary data

Journal Articles

Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin

Shannon E. Dunn, Sawsan Youssef, Matthew J. Goldstein, Thomas Prod'homme, Martin S. Weber, Scott S. Zamvil, Lawrence Steinman

J Exp Med (2006) 203 (2): 401–412.

https://doi.org/10.1084/jem.20051129

Published: 13 February 2006

View article titled, Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin

Includes: Supplementary data

Journal Articles

Optic Neuritis, A New Variant of Experimental Encephalomyelitis, A Durable Model for All Seasons, Now In Its Seventieth Year

Lawrence Steinman

J Exp Med (2003) 197 (9): 1065–1071.

https://doi.org/10.1084/jem.20030320

Published: 05 May 2003

View article titled, Optic Neuritis, A New Variant of Experimental Encephalomyelitis, A Durable Model for All Seasons, Now In Its Seventieth Year

Includes: Supplementary data

Journal Articles

Myelin-Specific Cd8 T Cells in the Pathogenesis of Experimental Allergic Encephalitis and Multiple Sclerosis

Lawrence Steinman

J Exp Med (2001) 194 (5): F27–F30.

https://doi.org/10.1084/jem.194.5.F27

Published: 04 September 2001

View article titled, Myelin-Specific Cd8 T Cells in the Pathogenesis of Experimental Allergic Encephalitis and Multiple Sclerosis

Journal Articles

Microbial Epitopes Act as Altered Peptide Ligands to Prevent Experimental Autoimmune Encephalomyelitis

Pedro J. Ruiz, Hideki Garren, David L. Hirschberg, Annette M. Langer-Gould, Mia Levite, Marcela V. Karpuj, Scott Southwood, Alessandro Sette, Paul Conlon, Lawrence Steinman

J Exp Med (1999) 189 (8): 1275–1284.

https://doi.org/10.1084/jem.189.8.1275

Published: 19 April 1999

View article titled, Microbial Epitopes Act as Altered Peptide Ligands to Prevent Experimental Autoimmune Encephalomyelitis

Journal Articles

Absence of “Original Antigenic Sin” in Autoimmunity Provides an Unforeseen Platform for Immune Therapy

Lawrence Steinman

J Exp Med (1999) 189 (7): 1021–1024.

https://doi.org/10.1084/jem.189.7.1021

Published: 05 April 1999

View article titled, Absence of “Original Antigenic Sin” in Autoimmunity Provides an Unforeseen Platform for Immune Therapy

Journal Articles

Some Misconceptions about Understanding Autoimmunity through Experiments with Knockouts

Lawrence Steinman

J Exp Med (1997) 185 (12): 2039–2041.

https://doi.org/10.1084/jem.185.12.2039

Published: 16 June 1997

View article titled, Some Misconceptions about Understanding Autoimmunity through Experiments with Knockouts

Journal Articles

Local Delivery of Interleukin 4 by Retrovirus-Transduced T Lymphocytes Ameliorates Experimental Autoimmune Encephalomyelitis

Michael K. Shaw, James B. Lorens, Archana Dhawan, Richard DalCanto, Harley Y. Tse, Alyssa B. Tran, Colleen Bonpane, Shanti L. Eswaran, Stefan Brocke, Nora Sarvetnick, Lawrence Steinman, Garry P. Nolan, C. Garrison Fathman

J Exp Med (1997) 185 (9): 1711–1714.

https://doi.org/10.1084/jem.185.9.1711

Published: 05 May 1997

View article titled, Local Delivery of Interleukin 4 by Retrovirus-Transduced T Lymphocytes Ameliorates Experimental Autoimmune Encephalomyelitis

NARROW

Experimental encephalomyelitis at age 90, still relevant and elucidating how viruses trigger disease

Correction: Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity

Mechanisms of action of therapeutic amyloidogenic hexapeptides in amelioration of inflammatory brain disease

Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

Peroxisome proliferator–activated receptor δ limits the expansion of pathogenic Th cells during central nervous system autoimmunity

A rush to judgment on Th17

Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity

Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity

Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin

Optic Neuritis, A New Variant of Experimental Encephalomyelitis, A Durable Model for All Seasons, Now In Its Seventieth Year

Myelin-Specific Cd8 T Cells in the Pathogenesis of Experimental Allergic Encephalitis and Multiple Sclerosis

Microbial Epitopes Act as Altered Peptide Ligands to Prevent Experimental Autoimmune Encephalomyelitis

Absence of “Original Antigenic Sin” in Autoimmunity Provides an Unforeseen Platform for Immune Therapy

Some Misconceptions about Understanding Autoimmunity through Experiments with Knockouts

Local Delivery of Interleukin 4 by Retrovirus-Transduced T Lymphocytes Ameliorates Experimental Autoimmune Encephalomyelitis

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