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Journal Articles

Interleukin-33–activated basophils promote asthma by regulating Th2 cell entry into lung tissue

Martijn J. Schuijs, Claudia M. Brenis Gomez, Fabian Bick, Justine Van Moorleghem, Manon Vanheerswynghels, Geert van Loo, Rudi Beyaert, David Voehringer, Richard M. Locksley, Hamida Hammad, Bart N. Lambrecht

J Exp Med (2024) 221 (12): e20240103.

https://doi.org/10.1084/jem.20240103

Published: 19 September 2024

View article titled, Interleukin-33–activated basophils promote asthma by regulating Th2 cell entry into lung tissue

Includes: Supplementary data

Journal Articles

Retinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites

In Special Collection:

Innate Lymphoid Cells 2024

Nikhat Shaikh, Alex Waterhölter, Ann-Christin Gnirck, Martina Becker, Virginia Adamiak, Lena Henneken, Malte Wunderlich, Wiebke Hartmann, Lara Linnemann, Tobias B. Huber, Christian F. Krebs, Ulf Panzer, Richard M. Locksley, Christoph Wilhelm, Minka Breloer, Jan-Eric Turner

J Exp Med (2023) 220 (12): e20221015.

https://doi.org/10.1084/jem.20221015

Published: 29 September 2023

View article titled, Retinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites

Journal Articles

Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth

In Special Collection:

Cytokines Collection 2021

Julia Gschwend, Samantha P.M. Sherman, Frederike Ridder, Xiaogang Feng, Hong-Erh Liang, Richard M. Locksley, Burkhard Becher, Christoph Schneider

J Exp Med (2021) 218 (10): e20210745.

https://doi.org/10.1084/jem.20210745

Published: 25 August 2021

View article titled, Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth

Journal Articles

Tissue-specific pathways extrude activated ILC2s to disseminate type 2 immunity

Roberto R. Ricardo-Gonzalez, Christoph Schneider, Chang Liao, Jinwoo Lee, Hong-Erh Liang, Richard M. Locksley

J Exp Med (2020) 217 (4): e20191172.

https://doi.org/10.1084/jem.20191172

Published: 07 February 2020

View article titled, Tissue-specific pathways extrude activated ILC2s to disseminate type 2 immunity

Journal Articles

ILC2s chew the fat

Roberto R. Ricardo-Gonzalez, Richard M. Locksley

J Exp Med (2019) 216 (9): 1972–1973.

https://doi.org/10.1084/jem.20191098

Published: 12 August 2019

View article titled, ILC2s chew the fat

Journal Articles

MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation

In Special Collection:

Regulating Transcription in Immunity and Inflammation

Priti B. Singh, Heather H. Pua, Hannah C. Happ, Christoph Schneider, Jakob von Moltke, Richard M. Locksley, Dirk Baumjohann, K. Mark Ansel

J Exp Med (2017) 214 (12): 3627–3643.

https://doi.org/10.1084/jem.20170545

Published: 09 November 2017

View article titled, MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation

Includes: Supplementary data

Journal Articles

Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s

Jakob von Moltke, Claire E. O’Leary, Nora A. Barrett, Yoshihide Kanaoka, K. Frank Austen, Richard M. Locksley

J Exp Med (2016) 214 (1): 27–37.

https://doi.org/10.1084/jem.20161274

Published: 23 December 2016

View article titled, Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s

Includes: Supplementary data

Journal Articles

IgE-activated basophils regulate eosinophil tissue entry by modulating endothelial function

Laurence E. Cheng, Brandon M. Sullivan, Lizett E. Retana, Christopher D.C. Allen, Hong-Erh Liang, Richard M. Locksley

J Exp Med (2015) 212 (4): 513–524.

https://doi.org/10.1084/jem.20141671

Published: 16 March 2015

View article titled, IgE-activated basophils regulate eosinophil tissue entry by modulating endothelial function

Includes: Supplementary data

Journal Articles

Leukotriene B₄ amplifies eosinophil accumulation in response to nematodes

Michael L. Patnode, Jennifer K. Bando, Matthew F. Krummel, Richard M. Locksley, Steven D. Rosen

J Exp Med (2014) 211 (7): 1281–1288.

https://doi.org/10.1084/jem.20132336

Published: 02 June 2014

View article titled, Leukotriene B4 amplifies eosinophil accumulation in response to nematodes

Includes: Supplementary data

Journal Articles

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

Ari B. Molofsky, Jesse C. Nussbaum, Hong-Erh Liang, Steven J. Van Dyken, Laurence E. Cheng, Alexander Mohapatra, Ajay Chawla, Richard M. Locksley

J Exp Med (2013) 210 (3): 535–549.

https://doi.org/10.1084/jem.20121964

Published: 18 February 2013

View article titled, Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

Includes: Supplementary data

Journal Articles

Nine lives: plasticity among T helper cell subsets

Richard M. Locksley

J Exp Med (2009) 206 (8): 1643–1646.

https://doi.org/10.1084/jem.20091442

Published: 27 July 2009

View article titled, Nine lives: plasticity among T helper cell subsets

Includes: Multimedia, Supplementary data

Journal Articles

Neutrophil histamine contributes to inflammation in mycoplasma pneumonia

Xiang Xu, Dongji Zhang, Hong Zhang, Paul J. Wolters, Nigel P. Killeen, Brandon M. Sullivan, Richard M. Locksley, Clifford A. Lowell, George H. Caughey

J Exp Med (2006) 203 (13): 2907–2917.

https://doi.org/10.1084/jem.20061232

Published: 11 December 2006

View article titled, Neutrophil histamine contributes to inflammation in mycoplasma pneumonia

Journal Articles

Correction

David Voehringer, Tiffany A. Reese, Xiaozhu Huang, Kanade Shinkai, Richard M. Locksley

J Exp Med (2006) 203 (6): 1617.

https://doi.org/10.1084/jem.20052448051806c

Published: 22 May 2006

View article titled, Correction

Journal Articles

Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system

David Voehringer, Tiffany A. Reese, Xiaozhu Huang, Kanade Shinkai, Richard M. Locksley

J Exp Med (2006) 203 (6): 1435–1446.

https://doi.org/10.1084/jem.20052448

Published: 15 May 2006

View article titled, Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system

Includes: Supplementary data

Journal Articles

Leishmania major LACK Antigen Is Required for Efficient Vertebrate Parasitization

Ben L. Kelly, Daniel B. Stetson, Richard M. Locksley

J Exp Med (2003) 198 (11): 1689–1698.

https://doi.org/10.1084/jem.20031162

Published: 01 December 2003

View article titled, Leishmania major LACK Antigen Is Required for Efficient Vertebrate Parasitization

Journal Articles

Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function

Daniel B. Stetson, Markus Mohrs, R. Lee Reinhardt, Jody L. Baron, Zhi-En Wang, Laurent Gapin, Mitchell Kronenberg, Richard M. Locksley

J Exp Med (2003) 198 (7): 1069–1076.

https://doi.org/10.1084/jem.20030630

Published: 06 October 2003

View article titled, Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function

Journal Articles

Cd1, Tuberculosis, and the Evolution of Major Histocompatibility Complex Molecules

Kanade Shinkai, Richard M. Locksley

J Exp Med (2000) 191 (6): 907–914.

https://doi.org/10.1084/jem.191.6.907

Published: 13 March 2000

View article titled, Cd1, Tuberculosis, and the Evolution of Major Histocompatibility Complex Molecules

Journal Articles

Altered Ligands Reveal Limited Plasticity in the T Cell Response to a Pathogenic Epitope

Sabine Pingel, Pascal Launois, Deborah J. Fowell, Christoph W. Turck, Scott Southwood, Alessandro Sette, Nicolas Glaichenhaus, Jacques A. Louis, Richard M. Locksley

J Exp Med (1999) 189 (7): 1111–1120.

https://doi.org/10.1084/jem.189.7.1111

Published: 05 April 1999

View article titled, Altered Ligands Reveal Limited Plasticity in the T Cell Response to a Pathogenic Epitope

Journal Articles

Genetic Regulation of Commitment to Interleukin 4 Production by a CD4⁺ T Cell–intrinsic Mechanism

Mark Bix, Zhi-En Wang, Bonnie Thiel, Nicholas J. Schork, Richard M. Locksley

J Exp Med (1998) 188 (12): 2289–2299.

https://doi.org/10.1084/jem.188.12.2289

Published: 21 December 1998

View article titled, Genetic Regulation of Commitment to Interleukin 4 Production by a CD4+ T Cell–intrinsic Mechanism

Journal Articles

Interferon γ Derived from CD4⁺ T Cells Is Sufficient to Mediate T Helper Cell Type 1 Development

Adil E. Wakil, Zhi-En Wang, James C. Ryan, Deborah J. Fowell, Richard M. Locksley

J Exp Med (1998) 188 (9): 1651–1656.

https://doi.org/10.1084/jem.188.9.1651

Published: 02 November 1998

View article titled, Interferon γ Derived from CD4+ T Cells Is Sufficient to Mediate T Helper Cell Type 1 Development

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Filters

Interleukin-33–activated basophils promote asthma by regulating Th2 cell entry into lung tissue

Retinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites

Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth

Tissue-specific pathways extrude activated ILC2s to disseminate type 2 immunity

ILC2s chew the fat

MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation

Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s

IgE-activated basophils regulate eosinophil tissue entry by modulating endothelial function

Leukotriene B₄ amplifies eosinophil accumulation in response to nematodes

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

Nine lives: plasticity among T helper cell subsets

Neutrophil histamine contributes to inflammation in mycoplasma pneumonia

Correction

Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system

Leishmania major LACK Antigen Is Required for Efficient Vertebrate Parasitization

Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function

Cd1, Tuberculosis, and the Evolution of Major Histocompatibility Complex Molecules

Altered Ligands Reveal Limited Plasticity in the T Cell Response to a Pathogenic Epitope

Genetic Regulation of Commitment to Interleukin 4 Production by a CD4⁺ T Cell–intrinsic Mechanism

Interferon γ Derived from CD4⁺ T Cells Is Sufficient to Mediate T Helper Cell Type 1 Development

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