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People & Ideas
SUN–KASH nuclear envelope bridges formed by WIP and SUN proteins are present in the plant branch of the tree of life but have functionally diverged from their opisthokont counterparts and are involved in nuclear morphology and RanGAP–nuclear envelope association.
Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane
Analysis of the lipid composition of influenza virus–infected cells provides support for the membrane raft-based biogenesis model.
Live imaging in Caenorhabditis elegans provides an unprecedented view of the chromatin-binding behavior and subcellular localization of origin replication licensing proteins during early embryogenesis.
Glucose remodels the post-translational modifications of the yeast arrestin-like protein Rod1 to promote glucose-induced transporter endocytosis.
The synaptic vesicle SNARE neuronal Synaptobrevin promotes endolysosomal degradation and prevents neurodegeneration
The synaptic v-SNARE n-Syb functions not only in synaptic vesicle exocytosis but also in delivery of protein-degrading enzymes to endosomes that are necessary to prevent protein aggregation and neurodegeneration.
Phosphatidic acid generation by DGK-α is essential for the localization of Rab11-coupling protein to invasive pseudopods and subsequent invasive migration by tumor cells.