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In Focus

Study reveals how yeast shuffle transporter molecules in response to glucose.

People & Ideas

Walther studies how cells use and store lipids to maintain membrane composition.




SUN–KASH nuclear envelope bridges formed by WIP and SUN proteins are present in the plant branch of the tree of life but have functionally diverged from their opisthokont counterparts and are involved in nuclear morphology and RanGAP–nuclear envelope association.

Analysis of the lipid composition of influenza virus–infected cells provides support for the membrane raft-based biogenesis model.

An alternative linkage is shown whereby FAK brings talin to nascent adhesions independent of talin binding to β1 integrins.


Live imaging in Caenorhabditis elegans provides an unprecedented view of the chromatin-binding behavior and subcellular localization of origin replication licensing proteins during early embryogenesis.

Glucose remodels the post-translational modifications of the yeast arrestin-like protein Rod1 to promote glucose-induced transporter endocytosis.

The synaptic v-SNARE n-Syb functions not only in synaptic vesicle exocytosis but also in delivery of protein-degrading enzymes to endosomes that are necessary to prevent protein aggregation and neurodegeneration.

Phosphatidic acid generation by DGK-α is essential for the localization of Rab11-coupling protein to invasive pseudopods and subsequent invasive migration by tumor cells.


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