Skip Nav Destination
Article
Arc controls organ architecture through modulation of Crb and MyoII
Kim et al. report on Arc, a large PDZ domain–containing cell membrane–associated protein that controls Drosophila salivary gland architecture. Arc facilitates apical membrane delivery of Crumbs; in turn, Crumbs limits accumulation and activity of non-muscle myosin II to regulate the number of salivary gland cells that internalize at a given time.
Visualizing nuclear pore complex plasticity with pan-expansion microscopy
Morgan et al. demonstrate that pan-expansion microscopy is an exceptional tool for probing the molecular composition and structural plasticity of individual NPCs: they reveal LINC complex–dependent NPC diameter biases across the nuclear surface and changing nucleoporin positions in an ALS model.
