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Journal Articles

ERG responses to high-frequency flickers require FAT3 signaling in mouse retinal bipolar cells

In Special Collection:

Neuroscience Collection 2025

Evelyn C. Avilés, Sean K. Wang, Sarina Patel, Sebastian Cordero, Shuxiang Shi, Lucas Lin, Vladimir J. Kefalov, Lisa V. Goodrich, Constance L. Cepko, Yunlu Xue

J Gen Physiol (2025) 157 (2): e202413642.

https://doi.org/10.1085/jgp.202413642

Published: 04 February 2025

View article titled, ERG responses to high-frequency flickers require FAT3 signaling in mouse retinal bipolar cells

Includes: Supplementary data

Journal Articles

BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy

In Special Collection:

Molecular Insights into Membrane Protein Function , Neuroscience Collection 2023

Yanyan Geng, Ping Li, Alice Butler, Bill Wang, Lawrence Salkoff, Karl L. Magleby

J Gen Physiol (2023) 155 (5): e202213302.

https://doi.org/10.1085/jgp.202213302

Published: 30 March 2023

View article titled, BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy

Journal Articles

Role of ryanodine receptor 2 and FK506-binding protein 12.6 dissociation in pulmonary hypertension

Yong-Xiao Wang, Jorge Reyes-García, Annarita Di Mise, Yun-Min Zheng

J Gen Physiol (2023) 155 (3): e202213100.

https://doi.org/10.1085/jgp.202213100

Published: 10 January 2023

View article titled, Role of ryanodine receptor 2 and FK506-binding protein 12.6 dissociation in pulmonary hypertension

Journal Articles

Myosin essential light chain 1sa decelerates actin and thin filament gliding on β-myosin molecules

Jennifer Osten, Maral Mohebbi, Petra Uta, Faramarz Matinmehr, Tianbang Wang, Theresia Kraft, Mamta Amrute-Nayak, Tim Scholz

J Gen Physiol (2022) 154 (10): e202213149.

https://doi.org/10.1085/jgp.202213149

Published: 02 September 2022

View article titled, Myosin essential light chain 1sa decelerates actin and thin filament gliding on β-myosin molecules

Includes: Supplementary data

Journal Articles

ORAI3 is dispensable for store-operated Ca²⁺ entry and immune responses by lymphocytes and macrophages

Liwei Wang, Lucile Noyer, Yin-Hu Wang, Anthony Y. Tao, Wenyi Li, Jingjie Zhu, Pedro Saavedra, Syed T. Hoda, Jun Yang, Stefan Feske

J Gen Physiol (2022) 154 (10): e202213104.

https://doi.org/10.1085/jgp.202213104

Published: 21 July 2022

View article titled, ORAI3 is dispensable for store-operated Ca2+ entry and immune responses by lymphocytes and macrophages

Includes: Supplementary data

Journal Articles

Catecholamines are key modulators of ventricular repolarization patterns in the ball python (Python regius)

Bastiaan J.D. Boukens, William Joyce, Ditte Lind Kristensen, Ingeborg Hooijkaas, Aldo Jongejan, Tobias Wang, Bjarke Jensen

J Gen Physiol (2021) 154 (2): e202012761.

https://doi.org/10.1085/jgp.202012761

Published: 15 December 2021

View article titled, Catecholamines are key modulators of ventricular repolarization patterns in the ball python (Python regius)

Includes: Supplementary data

Journal Articles

A non-transmembrane channel formed by Ca²⁺-bound calsequestrin-2: Calcium Signaling and Excitation–Contraction in Cardiac, Skeletal and Smooth Muscle

Xue-Xin Fan, Zihao Liu, Hua Yu, Xinyi Huang, Chen Song, Xuefeng Guo, Shi-Qiang Wang

J Gen Physiol (2021) 154 (9): e2021ecc8.

https://doi.org/10.1085/jgp.2021ecc8

Published: 12 November 2021

View article titled, A non-transmembrane channel formed by Ca2+-bound calsequestrin-2: Calcium Signaling and Excitation–Contraction in Cardiac, Skeletal and Smooth Muscle

Journal Articles

ML277 regulates KCNQ1 single-channel amplitudes and kinetics, modified by voltage sensor state

Jodene Eldstrom, Donald A. McAfee, Ying Dou, Yundi Wang, David Fedida

J Gen Physiol (2021) 153 (12): e202112969.

https://doi.org/10.1085/jgp.202112969

Published: 12 October 2021

View article titled, ML277 regulates KCNQ1 single-channel amplitudes and kinetics, modified by voltage sensor state

Journal Articles

Mechanical dysfunction of the sarcomere induced by a pathogenic mutation in troponin T drives cellular adaptation

Sarah R. Clippinger, Paige E. Cloonan, Wei Wang, Lina Greenberg, W. Tom Stump, Paweorn Angsutararux, Jeanne M. Nerbonne, Michael J. Greenberg

J Gen Physiol (2021) 153 (5): e202012787.

https://doi.org/10.1085/jgp.202012787

Published: 15 April 2021

View article titled, Mechanical dysfunction of the sarcomere induced by a pathogenic mutation in troponin T drives cellular adaptation

Includes: Supplementary data

Journal Articles

DEG/ENaC/ASIC channels vary in their sensitivity to anti-hypertensive and non-steroidal anti-inflammatory drugs

In Special Collection:

Neuroscience Collection 2022

Sylvia Fechner, Isabel D’Alessandro, Lingxin Wang, Calvin Tower, Li Tao, Miriam B. Goodman

J Gen Physiol (2021) 153 (4): e202012655.

https://doi.org/10.1085/jgp.202012655

Published: 03 March 2021

View article titled, DEG/ENaC/ASIC channels vary in their sensitivity to anti-hypertensive and non-steroidal anti-inflammatory drugs

Journal Articles

Filament evanescence of myosin II and smooth muscle function

Lu Wang, Pasquale Chitano, Chun Y. Seow

J Gen Physiol (2021) 153 (3): e202012781.

https://doi.org/10.1085/jgp.202012781

Published: 19 February 2021

View article titled, Filament evanescence of myosin II and smooth muscle function

Journal Articles

Mechanisms of proton inhibition and sensitization of the cation channel TRPV3

In Special Collection:

Protons and Membrane Function

Haiyuan Wang, Pu Yang, Yungang Lu, Jin Wang, Jaepyo Jeon, Qiaochu Wang, Jin-Bin Tian, Bin Zang, Ye Yu, Michael X. Zhu

J Gen Physiol (2020) 153 (2): e202012663.

https://doi.org/10.1085/jgp.202012663

Published: 15 December 2020

View article titled, Mechanisms of proton inhibition and sensitization of the cation channel TRPV3

Journal Articles

Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation

In Special Collection:

Cardiac Physiology 2021

Hannah A. Ledford, Seojin Park, Duncan Muir, Ryan L. Woltz, Lu Ren, Phuong T. Nguyen, Padmini Sirish, Wenying Wang, Choong-Ryoul Sihn, Alfred L. George, Jr., Björn C. Knollmann, Ebenezer N. Yamoah, Vladimir Yarov-Yarovoy, Xiao-Dong Zhang, Nipavan Chiamvimonvat

J Gen Physiol (2020) 152 (12): e202012667.

https://doi.org/10.1085/jgp.202012667

Published: 19 November 2020

View article titled, Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation

Includes: Supplementary data

Journal Articles

Mechanism and potential sites of potassium interaction with glutamate transporters

Jiali Wang, Kaiqi Zhang, Puja Goyal, Christof Grewer

J Gen Physiol (2020) 152 (10): e202012577.

https://doi.org/10.1085/jgp.202012577

Published: 20 August 2020

View article titled, Mechanism and potential sites of potassium interaction with glutamate transporters

Includes: Supplementary data

Journal Articles

Depressed neuromuscular transmission causes weakness in mice lacking BK potassium channels

Xueyong Wang, Steven R.A. Burke, Robert J. Talmadge, Andrew A. Voss, Mark M. Rich

J Gen Physiol (2020) 152 (5): e201912526.

https://doi.org/10.1085/jgp.201912526

Published: 03 April 2020

View article titled, Depressed neuromuscular transmission causes weakness in mice lacking BK potassium channels

Journal Articles

Regulation of heart rate and the pacemaker current by phosphoinositide 3-kinase signaling

In Special Collection:

Electrical Signaling in the Nervous System and Heart , Ion channel modulation

Richard Z. Lin, Zhongju Lu, Evgeny P. Anyukhovsky, Ya-Ping Jiang, Hong Zhan Wang, Junyuan Gao, Michael R. Rosen, Lisa M. Ballou, Ira S. Cohen

J Gen Physiol (2019) 151 (8): 1051–1058.

https://doi.org/10.1085/jgp.201812293

Published: 19 June 2019

View article titled, Regulation of heart rate and the pacemaker current by phosphoinositide 3-kinase signaling

Includes: Supplementary data

Journal Articles

Mitoflash biogenesis and its role in the autoregulation of mitochondrial proton electrochemical potential

Gaomin Feng, Beibei Liu, Jinghang Li, Tianlei Cheng, Zhanglong Huang, Xianhua Wang, Heping (Peace) Cheng

J Gen Physiol (2019) 151 (6): 727–737.

https://doi.org/10.1085/jgp.201812176

Published: 15 March 2019

View article titled, Mitoflash biogenesis and its role in the autoregulation of mitochondrial proton electrochemical potential

Includes: Supplementary data

Journal Articles

Novel alanine serine cysteine transporter 2 (ASCT2) inhibitors based on sulfonamide and sulfonic acid ester scaffolds

Elias Ndaru, Rachel-Ann A. Garibsingh, YueYue Shi, Evan Wallace, Paul Zakrepine, Jiali Wang, Avner Schlessinger, Christof Grewer

J Gen Physiol (2019) 151 (3): 357–368.

https://doi.org/10.1085/jgp.201812276

Published: 04 February 2019

View article titled, Novel alanine serine cysteine transporter 2 (ASCT2) inhibitors based on sulfonamide and sulfonic acid ester scaffolds

Includes: Supplementary data

Journal Articles

Pore- and voltage sensor–targeted KCNQ openers have distinct state-dependent actions

Caroline K. Wang, Shawn M. Lamothe, Alice W. Wang, Runying Y. Yang, Harley T. Kurata

J Gen Physiol (2018) 150 (12): 1722–1734.

https://doi.org/10.1085/jgp.201812070

Published: 29 October 2018

View article titled, Pore- and voltage sensor–targeted KCNQ openers have distinct state-dependent actions

Journal Articles

Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers

Masataka Kawai, Tarek S. Karam, Justin Kolb, Li Wang, Henk L. Granzier

J Gen Physiol (2018) 150 (11): 1510–1522.

https://doi.org/10.1085/jgp.201812104

Published: 09 October 2018

View article titled, Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers

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ERG responses to high-frequency flickers require FAT3 signaling in mouse retinal bipolar cells

BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy

Role of ryanodine receptor 2 and FK506-binding protein 12.6 dissociation in pulmonary hypertension

Myosin essential light chain 1sa decelerates actin and thin filament gliding on β-myosin molecules

ORAI3 is dispensable for store-operated Ca²⁺ entry and immune responses by lymphocytes and macrophages

Catecholamines are key modulators of ventricular repolarization patterns in the ball python (Python regius)

A non-transmembrane channel formed by Ca²⁺-bound calsequestrin-2: Calcium Signaling and Excitation–Contraction in Cardiac, Skeletal and Smooth Muscle

ML277 regulates KCNQ1 single-channel amplitudes and kinetics, modified by voltage sensor state

Mechanical dysfunction of the sarcomere induced by a pathogenic mutation in troponin T drives cellular adaptation

DEG/ENaC/ASIC channels vary in their sensitivity to anti-hypertensive and non-steroidal anti-inflammatory drugs

Filament evanescence of myosin II and smooth muscle function

Mechanisms of proton inhibition and sensitization of the cation channel TRPV3

Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation

Mechanism and potential sites of potassium interaction with glutamate transporters

Depressed neuromuscular transmission causes weakness in mice lacking BK potassium channels

Regulation of heart rate and the pacemaker current by phosphoinositide 3-kinase signaling

Mitoflash biogenesis and its role in the autoregulation of mitochondrial proton electrochemical potential

Novel alanine serine cysteine transporter 2 (ASCT2) inhibitors based on sulfonamide and sulfonic acid ester scaffolds

Pore- and voltage sensor–targeted KCNQ openers have distinct state-dependent actions

Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers

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