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Inhibition of Ca_V1.4 channels by Ca_V3 channel antagonists ML218 and Z944

Jinglang Sun, Juan de la Rosa Vázquez, Adriana Hernández-González, Vladimir Yarov-Yarovoy, Amy Lee

J Gen Physiol (2026) 158 (2): e202513879.

https://doi.org/10.1085/jgp.202513879

Published: 05 January 2026

View article titled, Inhibition of CaV1.4 channels by CaV3 channel antagonists ML218 and Z944

Includes: Supplementary data

Journal Articles

Exploring voltage-gated sodium channel conformations and protein–protein interactions using AlphaFold2

Diego Lopez-Mateos, Kush Narang, Vladimir Yarov-Yarovoy

J Gen Physiol (2025) 158 (2): e202413705.

https://doi.org/10.1085/jgp.202413705

Published: 18 December 2025

View article titled, Exploring voltage-gated sodium channel conformations and protein–protein interactions using AlphaFold2

Includes: Supplementary data

Journal Articles

Elucidating molecular mechanisms of protoxin-II state-specific binding to the human Na_V1.7 channel

Khoa Ngo, Diego Lopez Mateos, Yanxiao Han, Kyle C. Rouen, Surl-Hee Ahn, Heike Wulff, Colleen E. Clancy, Vladimir Yarov-Yarovoy, Igor Vorobyov

J Gen Physiol (2023) 156 (2): e202313368.

https://doi.org/10.1085/jgp.202313368

Published: 21 December 2023

View article titled, Elucidating molecular mechanisms of protoxin-II state-specific binding to the human NaV1.7 channel

Includes: Supplementary data

Journal Articles

Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation

In Special Collection:

Cardiac Physiology 2021

Hannah A. Ledford, Seojin Park, Duncan Muir, Ryan L. Woltz, Lu Ren, Phuong T. Nguyen, Padmini Sirish, Wenying Wang, Choong-Ryoul Sihn, Alfred L. George, Jr., Björn C. Knollmann, Ebenezer N. Yamoah, Vladimir Yarov-Yarovoy, Xiao-Dong Zhang, Nipavan Chiamvimonvat

J Gen Physiol (2020) 152 (12): e202012667.

https://doi.org/10.1085/jgp.202012667

Published: 19 November 2020

View article titled, Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation

Includes: Supplementary data

Journal Articles

An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations

Ernesto Vargas, Vladimir Yarov-Yarovoy, Fatemeh Khalili-Araghi, William A. Catterall, Michael L. Klein, Mounir Tarek, Erik Lindahl, Klaus Schulten, Eduardo Perozo, Francisco Bezanilla, Benoît Roux

J Gen Physiol (2012) 140 (6): 587–594.

https://doi.org/10.1085/jgp.201210873

Published: 26 November 2012

View article titled, An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations

Includes: Supplementary data

Journal Articles

Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations

Yuanyuan Cui, Fan Yang, Xu Cao, Vladimir Yarov-Yarovoy, KeWei Wang, Jie Zheng

J Gen Physiol (2012) 139 (4): 273–283.

https://doi.org/10.1085/jgp.201110724

Published: 12 March 2012

View article titled, Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations

Includes: Multimedia, Supplementary data

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Inhibition of Ca_V1.4 channels by Ca_V3 channel antagonists ML218 and Z944

Exploring voltage-gated sodium channel conformations and protein–protein interactions using AlphaFold2

Elucidating molecular mechanisms of protoxin-II state-specific binding to the human Na_V1.7 channel

Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation

An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations

Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations

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