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Molecular Insights into Membrane Protein Function

This collection delves into the molecular evolution of membrane proteins, focusing on ion channels, transporters, and receptors. The articles explore a diverse range of topics, from the transport of metformin metabolites by small multidrug resistance proteins in bacteria to the distinct functional properties and pharmacology of honeybee voltage-gated calcium channels. Additional topics include the optimization of CFTR gating through its extracellular loop, the regulation of ion channel activation and inactivation and how mutations linked to epilepsy and channelopathies alter ion channel function. This collection has been curated to coincide with the 77th Annual Meeting of the Society of General Physiologists, “Molecular Evolution in the Membrane: Ion Channels, Transporters, and Receptors.”

You are invited to submit papers on the topic of the symposium through our call for papers, to be published throughout the year and highlighted in a special issue. Guest editors of the special issue are Lucy Forrest of the National Institutes of Health and Randy Stockbridge of the University of Michigan. They are assisted in handling the reviews of submitted manuscripts by JGP Associate Editors Chris Lingle of Washington University School of Medicine in St. Louis and Crina Nimigean of Weill Cornell Medicine. Learn more here.

We hope you enjoy reading the collection and welcome your feedback on X/Twitter at @JGenPhysiol. To learn more about JGP and to submit your research, please visit our or contact the editorial office.

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Image ©2023 Simon and Csanády

Special Collection Image
Cheyanne M. Lewis; Theanne N. Griffith
Meyer B. Jackson; Chung-Wei Chiang; Jinbo Cheng
Vamseedhar Rayaprolu; Heini M. Miettinen; William D. Baker; Victoria C. Young; Matthew Fisher; Gwendolyn Mueller; William O. Rankin; John T. Kelley; William J. Ratzan; Lee Min Leong; Joshua A. Davisson; Bradley J. Baker; Susy C. Kohout
Dana A. Page; Peter C. Ruben
Anaïs Bertaud; Thierry Cens; Alain Chavanieu; Sébastien Estaran; Matthieu Rousset; Lisa Soussi; Claudine Ménard; Akelsso Kadala; Claude Collet; Sébastien Dutertre; Patrick Bois; Pascal Gosselin-Badaroudine; Jean-Baptiste Thibaud; Julien Roussel; Michel Vignes; Mohamed Chahine; Pierre Charnet
Rachael M. Lucero; Kemal Demirer; Trevor Justin Yeh; Randy B. Stockbridge
Denis B. Tikhonov; Boris S. Zhorov
Christopher H. Thompson; Franck Potet; Tatiana V. Abramova; Jean-Marc DeKeyser; Nora F. Ghabra; Carlos G. Vanoye; John J. Millichap; Alfred L. George, Jr
Kayla M. Komondor; Rachel E. Bainbridge; Katherine G. Sharp; Anuradha R. Iyer; Joel C. Rosenbaum; Anne E. Carlson
Tibor G. Szanto; Ferenc Papp; Florina Zakany; Zoltan Varga; Carol Deutsch; Gyorgy Panyi
Kirin D. Gada; Jordie M. Kamuene; Aishwarya Chandrashekar; R. Charles Kissell; Anne K. Yauch; Leigh D. Plant
Nael A. McCarty
Yanyan Geng; Ping Li; Alice Butler; Bill Wang; Lawrence Salkoff; Karl L. Magleby
Márton A. Simon; László Csanády
Daniel T. Infield; Miranda E. Schene; Frederico S. Fazan; Grace D. Galles; Jason D. Galpin; Christopher A. Ahern

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