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Ion channel modulation

This collection explores the diverse themes within ion channel modulation from the level of molecular biophysics to cellular and organ physiology. Articles provide prospects for regulation of physiology and correction of pathophysiology.

Ion channels can be modulated by multiple mechanisms that include lipid action, membrane targeting, phosphorylation status and incorporation of auxiliary proteins. Disease can ensue when these processes go awry, but modulatory mechanisms also offer opportunities to remedy channel dysfunction.

Image © 2019 Yeh et al.

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Richard Z. Lin; Zhongju Lu; Evgeny P. Anyukhovsky; Ya-Ping Jiang; Hong Zhan Wang; Junyuan Gao; Michael R. Rosen; Lisa M. Ballou; Ira S. Cohen
DOI: 10.1085/jgp.201812293
Takushi Shimomura; Yoshihiro Kubo
DOI: 10.1085/jgp.201812285
Han-I Yeh; Liming Qiu; Yoshiro Sohma; Katja Conrath; Xiaoqin Zou; Tzyh-Chang Hwang
DOI: 10.1085/jgp.201912360
Jae Seung Lee; Hae-Jin Kweon; Hyosang Lee; Byung-Chang Suh
DOI: 10.1085/jgp.201812224
Alexandr V. Ilyaskin; Florian Sure; Viatcheslav Nesterov; Silke Haerteis; Christoph Korbmacher
DOI: 10.1085/jgp.201812291
Danna Morales; Tamara Hermosilla; Diego Varela
DOI: 10.1085/jgp.201812236
Kazuharu Furutani; Kunichika Tsumoto; I-Shan Chen; Kenichiro Handa; Yuko Yamakawa; Jon T. Sack; Yoshihisa Kurachi
DOI: 10.1085/jgp.201812192
Kevin Strange; Toshiki Yamada; Jerod S. Denton
DOI: 10.1085/jgp.201812138
Alistair G. Fryatt; Sudad Dayl; Anastasios Stavrou; Ralf Schmid; Richard J. Evans
DOI: 10.1085/jgp.201812108
Sara J. Codding; Matthew C. Trudeau
DOI: 10.1085/jgp.201812129
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