Ion channel modulation
This collection explores the diverse themes within ion channel modulation from the level of molecular biophysics to cellular and organ physiology. Articles provide prospects for regulation of physiology and correction of pathophysiology.
Ion channels can be modulated by multiple mechanisms that include lipid action, membrane targeting, phosphorylation status and incorporation of auxiliary proteins. Disease can ensue when these processes go awry, but modulatory mechanisms also offer opportunities to remedy channel dysfunction.
Image © 2019 Yeh et al.