Issues

Pulmonary dendritic cells: thinking globally, acting locally

Evidence that vitamin D₃ promotes mast cell–dependent reduction of chronic UVB-induced skin pathology in mice

Essential roles of sphingosine-1–phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema

microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia

Resistance to antiangiogenic therapy is directed by vascular phenotype, vessel stabilization, and maturation in malignant melanoma

Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion

IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection

Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent

Dynamic T cell migration program provides resident memory within intestinal epithelium

CCR6 is expressed on an IL-10–producing, autoreactive memory T cell population with context-dependent regulatory function

Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis

Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rβ1 isoform that enhances DC migration

Ras activation of Erk restores impaired tonic BCR signaling and rescues immature B cell differentiation

ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo

Tumor-reactive CD4⁺ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

Naive tumor-specific CD4⁺ T cells differentiated in vivo eradicate established melanoma

Heterozygous deficiency of δ-catenin impairs pathological angiogenesis

The nonpolymorphic MHC Qa-1^b mediates CD8⁺ T cell surveillance of antigen-processing defects