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Taha Merghoub
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Journal Articles

OX40L-expressing recombinant modified vaccinia virus Ankara induces potent antitumor immunity via reprogramming Tregs

In Special Collection:
Tumor Microenvironment and Metastasis 2023 , Cancer Immunotherapy Update 2024 , JEM Clinical Immunology Collection 2023
Ning Yang, Yi Wang, Shuaitong Liu, Shanza Baseer Tariq, Joseph M. Luna, Gregory Mazo, Adrian Tan, Tuo Zhang, Jiahu Wang, Wei Yan, John Choi, Anthony Rossi, Jenny Zhaoying Xiang, Charles M. Rice, Taha Merghoub, Jedd D. Wolchok, Liang Deng
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20221166.
https://doi.org/10.1084/jem.20221166
Published: 05 May 2023
View article titled, OX40L-expressing recombinant modified vaccinia virus Ankara induces potent antitumor immunity via reprogramming Tregs
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Includes: Supplementary data
Journal Articles

Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions

In Special Collection:
JEM Cancer Immunotherapy 2022 , JEM Clinical Immunology Collection 2022 , Mechanisms and Models of Cancer 2022 Update
Sara E. Schad, Andrew Chow, Levi Mangarin, Heng Pan, Jiajia Zhang, Nicholas Ceglia, Justina X. Caushi, Nicole Malandro, Roberta Zappasodi, Mathieu Gigoux, Daniel Hirschhorn, Sadna Budhu, Masataka Amisaki, Monica Arniella, David Redmond, Jamie Chaft, Patrick M. Forde, Justin F. Gainor, Matthew D. Hellmann, Vinod Balachandran, Sohrab Shah, Kellie N. Smith, Drew Pardoll, Olivier Elemento, Jedd D. Wolchok, Taha Merghoub
Journal: Journal of Experimental Medicine
J Exp Med (2022) 219 (6): e20212169.
https://doi.org/10.1084/jem.20212169
Published: 23 May 2022
View article titled, Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions
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Includes: Supplementary data
Journal Articles

Neutrophil phenotypes and functions in cancer: A consensus statement

In Special Collection:
JEM Cancer Immunotherapy 2022 , JEM Cancer Collection 2023 , Mechanisms and Models of Cancer 2022 Update
Daniela F. Quail, Borko Amulic, Monowar Aziz, Betsy J. Barnes, Evgeniy Eruslanov, Zvi G. Fridlender, Helen S. Goodridge, Zvi Granot, Andrés Hidalgo, Anna Huttenlocher, Mariana J. Kaplan, Ilaria Malanchi, Taha Merghoub, Etienne Meylan, Vivek Mittal, Mikael J. Pittet, Andrea Rubio-Ponce, Irina A. Udalova, Timo K. van den Berg, Denisa D. Wagner, Ping Wang, Arturo Zychlinsky, Karin E. de Visser, Mikala Egeblad, Paul Kubes
Journal: Journal of Experimental Medicine
Series: Cancer Focus
J Exp Med (2022) 219 (6): e20220011.
https://doi.org/10.1084/jem.20220011
Published: 06 May 2022
View article titled, Neutrophil phenotypes and functions in cancer: A consensus statement
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Journal Articles

Immunotherapy and the belly of the beast

Taha Merghoub, Jedd D. Wolchok
Journal: Journal of Experimental Medicine
J Exp Med (2014) 211 (12): 2327–2328.
https://doi.org/10.1084/jem.21112insight3
Published: 17 November 2014
View article titled, Immunotherapy and the belly of the beast
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Journal Articles

Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype

Daniel Hirschhorn-Cymerman, Sadna Budhu, Shigehisa Kitano, Cailian Liu, Feng Zhao, Hong Zhong, Alexander M. Lesokhin, Francesca Avogadri-Connors, Jianda Yuan, Yanyun Li, Alan N. Houghton, Taha Merghoub, Jedd D. Wolchok
Journal: Journal of Experimental Medicine
J Exp Med (2012) 209 (11): 2113–2126.
https://doi.org/10.1084/jem.20120532
Published: 24 September 2012
View article titled, Induction of tumoricidal function in CD4<sup>+</sup> T cells is associated with concomitant memory and terminally differentiated phenotype
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Journal Articles

Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

In Special Collection:
2018 Nobel Prize Collection
Sergio A. Quezada, Tyler R. Simpson, Karl S. Peggs, Taha Merghoub, Jelena Vider, Xiaozhou Fan, Ronald Blasberg, Hideo Yagita, Pawel Muranski, Paul A. Antony, Nicholas P. Restifo, James P. Allison
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (3): 637–650.
https://doi.org/10.1084/jem.20091918
Published: 15 February 2010
View article titled, Tumor-reactive CD4<sup>+</sup> T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
Open the PDF for Tumor-reactive CD4<sup>+</sup> T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts in another window
Includes: Supplementary data
Journal Articles

OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis

Daniel Hirschhorn-Cymerman, Gabrielle A. Rizzuto, Taha Merghoub, Adam D. Cohen, Francesca Avogadri, Alexander M. Lesokhin, Andrew D. Weinberg, Jedd D. Wolchok, Alan N. Houghton
Journal: Journal of Experimental Medicine
J Exp Med (2009) 206 (5): 1103–1116.
https://doi.org/10.1084/jem.20082205
Published: 04 May 2009
View article titled, OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis
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Includes: Supplementary data
Journal Articles

Self-antigen–specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response

Gabrielle A. Rizzuto, Taha Merghoub, Daniel Hirschhorn-Cymerman, Cailian Liu, Alexander M. Lesokhin, Diana Sahawneh, Hong Zhong, Katherine S. Panageas, Miguel-Angel Perales, Grégoire Altan-Bonnet, Jedd D. Wolchok, Alan N. Houghton
Journal: Journal of Experimental Medicine
J Exp Med (2009) 206 (4): 849–866.
https://doi.org/10.1084/jem.20081382
Published: 30 March 2009
View article titled, Self-antigen–specific CD8<sup>+</sup> T cell precursor frequency determines the quality of the antitumor immune response
Open the PDF for Self-antigen–specific CD8<sup>+</sup> T cell precursor frequency determines the quality of the antitumor immune response in another window
Includes: Supplementary data