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Volume 180, Issue 4

25 February 2008

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Cover Image

Cover Image

On the cover
ILK (red), a kinase that helps hook actin to integrins in focal adhesions, is also found on centrosomes, where it helps arrange spindle microtubules (green). See page 681.
Table of Contents
Editorial Board

ISSN 0021-9525

EISSN 1540-8140

In this Issue

In This Issue
Research Roundup
People & Ideas
Meeting Report
Comments
Reports
Articles
Corrections

In This Issue

Trafficking from cell surface to nuclear envelope

Nicole LeBrasseur

Quick hops on and off plus ends

Nicole LeBrasseur

An adhesion kinase on centrosomes

Nicole LeBrasseur

Losing odd chromosomes

Nicole LeBrasseur

Matching traffic and growth

Nicole LeBrasseur

Research Roundup

Embryos need Mom's nucleolus

Richard Robinson

T cells count and then decide

Richard Robinson

Reach out and gRab something

Richard Robinson

Self-assembly of the cell wall

Richard Robinson

Kinesin's parts pull together

Richard Robinson

People & Ideas

Brian Chait: Master of mass spectrometry

Ruth Williams

Meeting Report

Capital Cells: The American Society for Cell Biology, Washington, D.C., December 1–5, 2007

Nicole LeBrasseur,Ruth Williams

Comments

The wages of CIN

Karen W. Yuen,Arshad Desai

Reports

Examining the link between chromosomal instability and aneuploidy in human cells

Sarah L. Thompson,Duane A. Compton

Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis

Fang Yang,Sigrid Eckardt,N. Adrian Leu,K. John McLaughlin,Peijing Jeremy Wang

Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization

Andrew B. Fielding,Iveta Dobreva,Paul C. McDonald,Leonard J. Foster,Shoukat Dedhar

FOXO-regulated transcription restricts overgrowth of Tsc mutant organs

Kieran F. Harvey,Jaakko Mattila,Avi Sofer,F. Christian Bennett,Matthew R. Ramsey,Leif W. Ellisen,Oscar Puig,Iswar K. Hariharan

Nuclear polyglutamine-containing protein aggregates as active proteolytic centers

Min Chen,Lena Singer,Andrea Scharf,Anna von Mikecz

Identification of ERGIC-53 as an intracellular transport receptor of α₁-antitrypsin

Beat Nyfeler,Veronika Reiterer,Markus W. Wendeler,Eduard Stefan,Bin Zhang,Stephen W. Michnick,Hans-Peter Hauri

The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus

Auxiliadora Aguilera-Romero,Joanna Kaminska,Anne Spang,Howard Riezman,Manuel Muñiz

The JAK/STAT pathway positively regulates DPP signaling in the Drosophila germline stem cell niche

Liwei Wang,Zhouhua Li,Yu Cai

Dynamic behavior of GFP–CLIP-170 reveals fast protein turnover on microtubule plus ends

Katharina A. Dragestein,Wiggert A. van Cappellen,Jeffrey van Haren,George D. Tsibidis,Anna Akhmanova,Tobias A. Knoch,Frank Grosveld,Niels Galjart

Moesin and its activating kinase Slik are required for cortical stability and microtubule organization in mitotic cells

Sébastien Carreno,Ilektra Kouranti,Edith Szafer Glusman,Margaret T. Fuller,Arnaud Echard,François Payre

Four key signaling pathways mediating chemotaxis in Dictyostelium discoideum

Douwe M. Veltman,Ineke Keizer-Gunnik,Peter J.M. Van Haastert

Endosomal entry regulates Notch receptor activation in Drosophila melanogaster

Thomas Vaccari,Han Lu,Ritu Kanwar,Mark E. Fortini,David Bilder

Membrane-anchored growth factor, HB-EGF, on the cell surface targeted to the inner nuclear membrane

Miki Hieda,Mayumi Isokane,Michiko Koizumi,Chiduru Higashi,Taro Tachibana,Masachika Shudou,Tomohiko Taguchi,Yohki Hieda,Shigeki Higashiyama

Articles

SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the γ-tubulin–mediated addition of centriolar microtubules

Alexander Dammermann,Paul S. Maddox,Arshad Desai,Karen Oegema

IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis

Nadine Bakkar,Jingxin Wang,Katherine J. Ladner,Huating Wang,Jason M. Dahlman,Micheal Carathers,Swarnali Acharyya,Michael A. Rudnicki,Andrew D. Hollenbach,Denis C. Guttridge

Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1

Anastasia Blagoveshchenskaya,Fei Ying Cheong,Holger M. Rohde,Greta Glover,Andreas Knödler,Teresa Nicolson,Guido Boehmelt,Peter Mayinger

Ergosterol promotes pheromone signaling and plasma membrane fusion in mating yeast

Hui Jin,J. Michael McCaffery,Eric Grote

The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM

Chan Choo Yap,Dolora Wisco,Pekka Kujala,Zofia M. Lasiecka,Johanna T. Cannon,Michael C. Chang,Harald Hirling,Judith Klumperman,Bettina Winckler

Corrections

DNA-activated protein kinase functions in a newly observed S phase checkpoint that links histone mRNA abundance with DNA replication

Berndt Müller,Jane Blackburn,Carmen Feijoo,Xiujie Zhao,Carl Smythe

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