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Seth L. Masters
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Journal Articles

Primary disorders of polyubiquitination: Dual roles in autoinflammation and immunodeficiency

András N. Spaan, Bertrand Boisson, Seth L. Masters
Journal: Journal of Experimental Medicine
Series: Genes and Immunity Focus
J Exp Med (2025) 222 (5): e20241047.
https://doi.org/10.1084/jem.20241047
Published: 15 April 2025
View articletitled, Primary disorders of polyubiquitination: Dual roles in autoinflammation and immunodeficiency
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Journal Articles

Dominant negative OTULIN-related autoinflammatory syndrome

In Special Collection:
JEM Clinical Immunology Collection 2024 , Genes and Immunity , 2024: The Year in Experimental Medicine
Sophia Davidson, Yuri Shibata, Sophie Collard, Hongyu Zheng, Klara Kong, June M. Sun, Pawat Laohamonthonkul, Anthony Cerra, Tobias Kratina, CIRCA, AADRY, Margaret W.Y. Li, Carolyn Russell, Anna van Beek, Edwin P. Kirk, Rebecca Walsh, Jubran Alqanatish, Abdullah Almojali, Wafaa Alsuwairi, Abdulrahman Alrasheed, Najoua Lalaoui, Paul E. Gray, David Komander, Seth L. Masters
Journal: Journal of Experimental Medicine
J Exp Med (2024) 221 (6): e20222171.
https://doi.org/10.1084/jem.20222171
Published: 17 April 2024
View articletitled, Dominant negative OTULIN-related autoinflammatory syndrome
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Includes: Supplementary data
Journal Articles

Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity

In Special Collection:
Autoimmunity 2024 , JEM Immunology Collection 2024
Yaoyuan Zhang, Rhiannon Morris, Grant J. Brown, Ayla May D. Lorenzo, Xiangpeng Meng, Nadia J. Kershaw, Pamudika Kiridena, Gaétan Burgio, Simon Gross, Jean Y. Cappello, Qian Shen, Hao Wang, Cynthia Turnbull, Tom Lea-Henry, Maurice Stanley, Zhijia Yu, Fiona D. Ballard, Aaron Chuah, James C. Lee, Ann-Maree Hatch, Anselm Enders, Seth L. Masters, Alexander P. Headley, Peter Trnka, Dominic Mallon, Jeffery T. Fletcher, Giles D. Walters, Mario Šestan, Marija Jelušić, Matthew C. Cook, Vicki Athanasopoulos, David A. Fulcher, Jeffrey J. Babon, Carola G. Vinuesa, Julia I. Ellyard
Journal: Journal of Experimental Medicine
J Exp Med (2024) 221 (4): e20221080.
https://doi.org/10.1084/jem.20221080
Published: 28 February 2024
View articletitled, Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity
Open the PDF for Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity in another window
Includes: Supplementary data
Journal Articles

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome

Viola Neudecker, Moritz Haneklaus, Owen Jensen, Ludmila Khailova, Joanne C. Masterson, Hazel Tye, Kathryn Biette, Paul Jedlicka, Kelley S. Brodsky, Mark E. Gerich, Matthias Mack, Avril A.B. Robertson, Matthew A. Cooper, Glenn T. Furuta, Charles A. Dinarello, Luke A. O’Neill, Holger K. Eltzschig, Seth L. Masters, Eóin N. McNamee
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (6): 1737–1752.
https://doi.org/10.1084/jem.20160462
Published: 09 May 2017
View articletitled, Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome
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Includes: Supplementary data
Journal Articles

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β

Man Lyang Kim, Jae Jin Chae, Yong Hwan Park, Dominic De Nardo, Roslynn A. Stirzaker, Hyun-Ja Ko, Hazel Tye, Louise Cengia, Ladina DiRago, Donald Metcalf, Andrew W. Roberts, Daniel L. Kastner, Andrew M. Lew, Dena Lyras, Benjamin T. Kile, Ben A. Croker, Seth L. Masters
Journal: Journal of Experimental Medicine
J Exp Med (2015) 212 (6): 927–938.
https://doi.org/10.1084/jem.20142384
Published: 25 May 2015
View articletitled, Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β
Open the PDF for Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β in another window