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Genes and Immunity
This collection highlights recent advances in the field of human inborn errors of immunity. You will find research on immune dysregulations with genetic bases leading to autoimmunity, inflammation, and increased susceptibility to infections.
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Image © 2025 Simchoni et al.
Review | Genes and Immunity Focus
Elizabeth G. Schmitz; Malachi Griffith; Obi L. Griffith; Megan A. Cooper
Article
Bradly M. Bauman; Jeffrey R. Stinson; Melissa A. Kallarakal; Lei Haley Huang; Andrew M. Frank; Gauthaman Sukumar; Nermina Saucier; Clifton L. Dalgard; Alice Y. Chan; Joshua D. Milner; Megan A. Cooper; Andrew L. Snow
Article
Evi Duthoo; Elien Beyls; Lynn Backers; Thorkell Gudjónsson; Peiquan Huang; Leander Jonckheere; Sebastian Riemann; Bram Parton; Likun Du; Veronique Debacker; Marieke De Bruyne; Levi Hoste; Ans Baeyens; Anne Vral; Eva Van Braeckel; Jens Staal; Geert Mortier; Tessa Kerre; Qiang Pan-Hammarström; Claus S. Sørensen; Filomeen Haerynck; Kathleen B.M. Claes; Simon J. Tavernier
Brief Definitive Report
Noa Simchoni; Shogo Koide; Maryel Likhite; Yoshihiko Kuchitsu; Senkottuvelan Kadirvel; Christopher S. Law; Brett M. Elicker; Santosh Kurra; Margaret Mei-Kay Wong; Bo Yuan; Alice Grossi; Ronald M. Laxer; Stefano Volpi; Dilan Dissanayake; Tomohiko Taguchi; David B. Beck; Tiphanie P. Vogel; Anthony K. Shum
Article
Quentin Riller; Boris Sorin; Charline Courteille; Duong Ho-Nhat; Tom Le Voyer; Jean-Christophe Debray; Marie-Claude Stolzenberg; Muriel Schmutz; Olivier Pellé; Thomas Becquard; María Rodrigo Riestra; Laureline Berteloot; Mélanie Migaud; Laure Delage; Marie Jeanpierre; Charlotte Boussard; Camille Brunaud; Aude Magérus; Charles Bretot; Victor Michel; Camille Roux; Capucine Picard; Cécile Masson; Christine Bole-Feysot; Nicolas Cagnard; Aurélien Corneau; Isabelle Meyts; Véronique Baud; Jean-Laurent Casanova; Alain Fischer; Emmanuel Dejardin; Anne Puel; Cécile Boulanger; Bénédicte Neven; Frédéric Rieux-Laucat
Article
Fahd Al Qureshah; Jérémie Le Pen; Nicole A. de Weerd; Marcela Moncada-Velez; Marie Materna; Daniel C. Lin; Baptiste Milisavljevic; Fernanda Vianna; Lucy Bizien; Lazaro Lorenzo; Marc Lecuit; Jean-David Pommier; Sevgi Keles; Tayfun Ozcelik; Sigifredo Pedraza-Sanchez; Nicolas de Prost; Loubna El Zein; Hassan Hammoud; Lisa F.P. Ng; Rabih Halwani; Narjes Saheb Sharif-Askari; Yu Lung Lau; Anthony R. Tam; Neha Singh; Sagar Bhattad; Yackov Berkun; Wasun Chantratita; Raúl Aguilar-López; Mohammad Shahrooei; COVID-19 HGE Consortium; SEAe Consortium; Laurent Abel; Paul Bastard; Emmanuelle Jouanguy; Vivien Béziat; Peng Zhang; Charles M. Rice; Aurélie Cobat; Shen-Ying Zhang; Paul J. Hertzog; Jean-Laurent Casanova; Qian Zhang
Article
Evangelos Bellos; Dilys Santillo; Pierre Vantourout; Heather R. Jackson; Amedine Duret; Henry Hearn; Yoann Seeleuthner; Estelle Talouarn; Stephanie Hodeib; Harsita Patel; Oliver Powell; Sophya Yeoh; Sobia Mustafa; Dominic Habgood-Coote; Samuel Nichols; Leire Estramiana Elorrieta; Giselle D’Souza; Victoria J. Wright; Diego Estrada-Rivadeneyra; Adriana H. Tremoulet; Kirsten B. Dummer; Stejara A. Netea; Antonio Condino-Neto; Yu Lung Lau; Esmeralda Núñez Cuadros; Julie Toubiana; Marisol Holanda Pena; Frédéric Rieux-Laucat; Charles-Edouard Luyt; Filomeen Haerynck; Jean Louis Mège; Samya Chakravorty; Elie Haddad; Marie-Paule Morin; Özge Metin Akcan; Sevgi Keles; Melike Emiroglu; Gulsum Alkan; Sadiye Kübra Tüter Öz; Sefika Elmas Bozdemir; Guillaume Morelle; Alla Volokha; Yasemin Kendir-Demirkol; Betul Sözeri; Taner Coskuner; Aysun Yahsi; Belgin Gulhan; Saliha Kanik-Yuksek; Gulsum Iclal Bayhan; Aslinur Ozkaya-Parlakay; Osman Yesilbas; Nevin Hatipoglu; Tayfun Ozcelik; Alexandre Belot; Emilie Chopin; Vincent Barlogis; Esra Sevketoglu; Emin Menentoglu; Zeynep Gokce Gayretli Aydin; Marketa Bloomfield; Suzan A. AlKhater; Cyril Cyrus; Yuriy Stepanovskiy; Anastasiia Bondarenko; Fatma Nur Öz; Meltem Polat; Jiří Fremuth; Jan Lebl; Amyrath Geraldo; Emmanuelle Jouanguy; COVID-19 Human Genetic Effort; DIAMONDS; EUCLIDS; Michael J. Carter; Paul Wellman; Mark Peters; Rebeca Pérez de Diego; Lindsey Ann Edwards; Christopher Chiu; Mahdad Noursadeghi; Alexandre Bolze; Chisato Shimizu; Myrsini Kaforou; Melissa Shea Hamilton; Jethro A. Herberg; Erica G. Schmitt; Agusti Rodriguez-Palmero; Aurora Pujol; Jihoon Kim; Aurélie Cobat; Laurent Abel; Shen-Ying Zhang; Jean-Laurent Casanova; Taco W. Kuijpers; Jane C. Burns; Michael Levin; Adrian C. Hayday; Vanessa Sancho-Shimizu
Article
Elena Blanco; Carme Camps; Sameer Bahal; Mohit D. Kerai; Matteo P. Ferla; Adam M. Rochussen; Adam E. Handel; Zainab M. Golwala; Helena Spiridou Goncalves; Susanne Kricke; Fabian Klein; Fang Zhang; Federica Zinghirino; Grace Evans; Thomas M. Keane; Sabrina Lizot; Maaike A.A. Kusters; Mildred A. Iro; Sanjay V. Patel; Emma C. Morris; Siobhan O. Burns; Ruth Radcliffe; Pradeep Vasudevan; Arthur Price; Olivia Gillham; Gabriel E. Valdebenito; Grant S. Stewart; Austen Worth; Stuart P. Adams; Michael Duchen; Isabelle André; David J. Adams; Giorgia Santili; Kimberly C. Gilmour; Georg A. Holländer; E. Graham Davies; Jenny C. Taylor; Gillian M. Griffiths; Adrian J. Thrasher; Fatima Dhalla; Alexandra Y. Kreins
Article
Anne Doye; Paul Chaintreuil; Chantal Lagresle-Peyrou; Ludovic Batistic; Valentine Marion; Patrick Munro; Celine Loubatier; Rayana Chirara; Nataël Sorel; Boris Bessot; Pauline Bronnec; Julie Contenti; Johan Courjon; Valerie Giordanengo; Arnaud Jacquel; Pascal Barbry; Marie Couralet; Nathalie Aladjidi; Alain Fischer; Marina Cavazzana; Coralie Mallebranche; Orane Visvikis; Sven Kracker; Despina Moshous; Els Verhoeyen; Laurent Boyer
Brief Definitive Report
Clémence David; Carlos A. Arango-Franco; Mihaly Badonyi; Julien Fouchet; Gillian I. Rice; Blaise Didry-Barca; Lucie Maisonneuve; Luis Seabra; Robin Kechiche; Cécile Masson; Aurélie Cobat; Laurent Abel; Estelle Talouarn; Vivien Béziat; Caroline Deswarte; Katie Livingstone; Carle Paul; Gulshan Malik; Alison Ross; Jane Adam; Jo Walsh; Sathish Kumar; Damien Bonnet; Christine Bodemer; Brigitte Bader-Meunier; Joseph A. Marsh; Jean-Laurent Casanova; Yanick J. Crow; Bénédicte Manoury; Marie-Louise Frémond; Jonathan Bohlen; Alice Lepelley
Article
Kelsey A. Toth; Erica G. Schmitt; Ana Kolicheski; Zev J. Greenberg; Elizabeth Levendosky; Nermina Saucier; Kelsey Trammel; Vasileios Oikonomou; Michail S. Lionakis; Eynav Klechevsky; Brian S. Kim; Laura G. Schuettpelz; Naresha Saligrama; Megan A. Cooper
Article
Victoria E. Rael; Julian A. Yano; John P. Huizar; Leianna C. Slayden; Madeleine A. Weiss; Elizabeth A. Turcotte; Jacob M. Terry; Wenqi Zuo; Isabelle Thiffault; Tomi Pastinen; Emily G. Farrow; Janda L. Jenkins; Mara L. Becker; Stephen C. Wong; Anne M. Stevens; Catherine Otten; Eric J. Allenspach; Devon E. Bonner; Jonathan A. Bernstein; Matthew T. Wheeler; Robert A. Saxton; Undiagnosed Diseases Network; Bo Liu; Olivia Majer; Gregory M. Barton
Article
Yukiko Takeda; Masahiro Ueki; Junpei Matsuhiro; Erik Walinda; Takayuki Tanaka; Masafumi Yamada; Hiroaki Fujita; Shunichiro Takezaki; Ichiro Kobayashi; Sakura Tamaki; Sanae Nagata; Noriko Miyake; Naomichi Matsumoto; Mitsujiro Osawa; Takahiro Yasumi; Toshio Heike; Fumiaki Ohtake; Megumu K. Saito; Junya Toguchida; Junko Takita; Tadashi Ariga; Kazuhiro Iwai
Brief Definitive Report
Sophia Davidson; Yuri Shibata; Sophie Collard; Hongyu Zheng; Klara Kong; June M. Sun; Pawat Laohamonthonkul; Anthony Cerra; Tobias Kratina; CIRCA; AADRY; Margaret W.Y. Li; Carolyn Russell; Anna van Beek; Edwin P. Kirk; Rebecca Walsh; Jubran Alqanatish; Abdullah Almojali; Wafaa Alsuwairi; Abdulrahman Alrasheed; Najoua Lalaoui; Paul E. Gray; David Komander; Seth L. Masters
Article
Michael E. Horesh; Marta Martin-Fernandez; Conor Gruber; Sofija Buta; Tom Le Voyer; Eve Puzenat; Harry Lesmana; Yiming Wu; Ashley Richardson; David Stein; Stephanie Hodeib; Mariam Youssef; Jacob A. Kurowski; Elizabeth Feuille; Luis A. Pedroza; Ramsay L. Fuleihan; Alexandria Haseley; Alain Hovnanian; Pierre Quartier; Jérémie Rosain; Georgina Davis; Daniel Mullan; O’Jay Stewart; Roosheel Patel; Angelica E. Lee; Rebecca Rubinstein; Leyla Ewald; Nikhil Maheshwari; Virginia Rahming; Ivan K. Chinn; James R. Lupski; Jordan S. Orange; Vanessa Sancho-Shimizu; Jean-Laurent Casanova; Noura S. Abul-Husn; Yuval Itan; Joshua D. Milner; Jacinta Bustamante; Dusan Bogunovic
Article
Antoine Guérin; Marcela Moncada-Vélez; Katherine Jackson; Masato Ogishi; Jérémie Rosain; Mathieu Mancini; David Langlais; Andrea Nunez; Samantha Webster; Jesse Goyette; Taushif Khan; Nico Marr; Danielle T. Avery; Geetha Rao; Tim Waterboer; Birgitta Michels; Esmeralda Neves; Cátia Iracema Morais; Jonathan London; Stéphanie Mestrallet; Pierre Quartier dit Maire; Bénédicte Neven; Franck Rapaport; Yoann Seeleuthner; Atar Lev; Amos J. Simon; Jorge Montoya; Ortal Barel; Julio Gómez-Rodríguez; Julio C. Orrego; Anne-Sophie L’Honneur; Camille Soudée; Jessica Rojas; Alejandra C. Velez; Irini Sereti; Benjamin Terrier; Nancy Marin; Luis F. García; Laurent Abel; Stéphanie Boisson-Dupuis; Joel Reis; Antonio Marinho; Andrea Lisco; Emilia Faria; Christopher C. Goodnow; Julia Vasconcelos; Vivien Béziat; Cindy S. Ma; Raz Somech; Jean-Laurent Casanova; Jacinta Bustamante; Jose Luis Franco; Stuart G. Tangye
