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Issues

Volume 206, Issue 5
11 May 2009
Journal of Experimental Medicine Cover Image for Volume 206, Issue 5
All Issues
ISSN 0022-1007
EISSN 1540-9538

Editorial

JEM's 2009 Tune-up
Heather L. Van Epps
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A challenge to Goliath
Mike Rossner
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In This Issue

Follicular T-to-be
Amy Maxmen
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Mast cells master a rash
Amy Maxmen
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HO-1's versatility
Amy Maxmen
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Bulldozing angiogenesis
Amy Maxmen
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People & Ideas

Shane Crotty: Exploring immune memory
Kira Heller

Virologist and published author Shane Crotty sees immune memory as the key to making a better vaccine.

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Commentary

A20 takes on tumors: tumor suppression by an ubiquitin-editing enzyme
Barbara A. Malynn,Averil Ma
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Brief Definitive Report

TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma
Roland Schmitz,Martin-Leo Hansmann,Verena Bohle,Jose Ignacio Martin-Subero,Sylvia Hartmann,Gunhild Mechtersheimer,Wolfram Klapper,Inga Vater,Maciej Giefing,Stefan Gesk,Jens Stanelle,Reiner Siebert,Ralf Küppers
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T follicular helper cells differentiate from Th2 cells in response to helminth antigens
Arielle Glatman Zaretsky,Justin J. Taylor,Irah L. King,Fraser A. Marshall,Markus Mohrs,Edward J. Pearce
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IL-4–producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells
Irah L. King,Markus Mohrs
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Identification and characterization of IL-10/IFN-γ–producing effector-like T cells with regulatory function in human blood
Barbara Häringer,Laura Lozza,Bodo Steckel,Jens Geginat
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A 220-nucleotide deletion of the intronic enhancer reveals an epigenetic hierarchy in immunoglobulin heavy chain locus activation
Tirtha Chakraborty,Thomas Perlot,Ramesh Subrahmanyam,Anant Jani,Peter H. Goff,Yu Zhang,Irina Ivanova,Frederick W. Alt,Ranjan Sen
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In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes
Helen J. Lachmann,Philip Lowe,Sandra Daniela Felix,Christiane Rordorf,Kieron Leslie,Sheril Madhoo,Helmut Wittkowski,Stephan Bek,Nicole Hartmann,Sophie Bosset,Philip N. Hawkins,Thomas Jung
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Article

Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria
Yuumi Nakamura,Naotomo Kambe,Megumu Saito,Ryuta Nishikomori,Yun-Gi Kim,Makoto Murakami,Gabriel Núñez,Hiroyuki Matsue
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Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination
Isabelle Robert,Françoise Dantzer,Bernardo Reina-San-Martin
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The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription
Hong Ming Shen,Michael G. Poirier,Michael J. Allen,Justin North,Ratnesh Lal,Jonathan Widom,Ursula Storb
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Ikaros controls isotype selection during immunoglobulin class switch recombination
MacLean Sellars,Bernardo Reina-San-Martin,Philippe Kastner,Susan Chan
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M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis
Yoshiaki Kubota,Keiyo Takubo,Takatsune Shimizu,Hiroaki Ohno,Kazuo Kishi,Masabumi Shibuya,Hideyuki Saya,Toshio Suda
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OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis
Daniel Hirschhorn-Cymerman,Gabrielle A. Rizzuto,Taha Merghoub,Adam D. Cohen,Francesca Avogadri,Alexander M. Lesokhin,Andrew D. Weinberg,Jedd D. Wolchok,Alan N. Houghton
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Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1
Brandon F. Keele,Hui Li,Gerald H. Learn,Peter Hraber,Elena E. Giorgi,Truman Grayson,Chuanxi Sun,Yalu Chen,Wendy W. Yeh,Norman L. Letvin,John R. Mascola,Gary J. Nabel,Barton F. Haynes,Tanmoy Bhattacharya,Alan S. Perelson,Bette T. Korber,Beatrice H. Hahn,George M. Shaw
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Kallikrein 5 induces atopic dermatitis–like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome
Anaïs Briot,Céline Deraison,Matthieu Lacroix,Chrystelle Bonnart,Aurélie Robin,Céline Besson,Pierre Dubus,Alain Hovnanian
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Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis
Chun Geun Lee,Dominik Hartl,Gap Ryol Lee,Barbara Koller,Hiroshi Matsuura,Carla A. Da Silva,Myung Hyun Sohn,Lauren Cohn,Robert J. Homer,Alexander A. Kozhich,Alison Humbles,Jennifer Kearley,Anthony Coyle,Geoffrey Chupp,Jennifer Reed,Richard A. Flavell,Jack A. Elias
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Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production
Sotiria Tzima,Panayiotis Victoratos,Ksanthi Kranidioti,Maria Alexiou,George Kollias
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Neutropenia with impaired host defense against microbial infection in mice lacking androgen receptor
Kuang-Hsiang Chuang,Saleh Altuwaijri,Gonghui Li,Jiann-Jyh Lai,Chin-Yi Chu,Kuo-Pao Lai,Hung-Yun Lin,Jong-Wei Hsu,Peter Keng,Ming-Chi Wu,Chawnshang Chang
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Correction

Alternatively activated macrophage-derived RELM-α is a negative regulator of type 2 inflammation in the lung
Meera G. Nair,Yurong Du,Jacqueline G. Perrigoue,Colby Zaph,Justin J. Taylor,Michael Goldschmidt,Gary P. Swain,George D. Yancopoulos,David M. Valenzuela,Andrew Murphy,Margaret Karow,Sean Stevens,Edward J. Pearce,David Artis
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Antibody to the dendritic cell surface activation antigen CD83 prevents acute graft-versus-host disease
John Wilson,Hannah Cullup,Rohan Lourie,Yonghua Sheng,Anna Palkova,Kristen J. Radford,Anne M. Dickinson,Alison M. Rice,Derek N.J. Hart,David J. Munster
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Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria
Yuumi Nakamura,Naotomo Kambe,Megumu Saito,Ryuta Nishikomori,Yun-Gi Kim,Makoto Murakami,Gabriel Núñez,Hiroyuki Matsue
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Retraction

Role of interleukin 12 and costimulators in T cell anergy in vivo
Luk Van Parijs,Victor L. Perez,Andre Biuckians,Robert G. Maki,Cheryl A. London,Abul K. Abbas
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