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Volume 190, Issue 6

20 September 1999

Cover Image

Cover Image

Cover picture: Three days after antigenic stimulation, a subset of dendritic cells (blue) interacts with B cells (red) and T cells (green) in the outer zone of a primary lymphoid follicle. These dendritic cells, identified by their capacity to bind the mannose receptor, have the unique capacity to provide peptide to T cells and intact antigen to B cells in order to initiate humoral responses in vivo. See related article in this issue by Berney et al., pp. 851860.

Table of Contents

Editorial Board

ISSN 0022-1007

EISSN 1540-9538

In this Issue

Article

Brief Definitive Report

Article

Distinct Signal Thresholds for the Unique Antigen Receptor–Linked Gene Expression Programs in Mature and Immature B Cells

Robert J. Benschop,Doron Melamed,David Nemazee,John C. Cambier

View Articletitled, Distinct Signal Thresholds for the Unique Antigen Receptor–Linked Gene Expression Programs in Mature and Immature B Cells

The Final Maturation of at Least Some Single-Positive Cd4^hiThymocytes Does Not Require T Cell Receptor–Major Histocompatibility Complex Contact

Ruben Dyall,Janko Nikolić-Z̆ugić

View Articletitled, The Final Maturation of at Least Some Single-Positive Cd4hiThymocytes Does Not Require T Cell Receptor–Major Histocompatibility Complex Contact

Cytotoxic T Lymphocyte Antigen 4 (Ctla-4) Engagement Delivers an Inhibitory Signal through the Membrane-Proximal Region in the Absence of the Tyrosine Motif in the Cytoplasmic Tail

Chiaki Nakaseko,Shoichiro Miyatake,Tomohiko Iida,Satoru Hara,Ryo Abe,Hiroshi Ohno,Takashi Saito

View Articletitled, Cytotoxic T Lymphocyte Antigen 4 (Ctla-4) Engagement Delivers an Inhibitory Signal through the Membrane-Proximal Region in the Absence of the Tyrosine Motif in the Cytoplasmic Tail

In Vivo Expression of Natural Killer Cell Inhibitory Receptors by Human Melanoma–Specific Cytolytic T Lymphocytes

Daniel E. Speiser,Mikaël J. Pittet,Danila Valmori,Rod Dunbar,Donata Rimoldi,Danielle Liénard,H. Robson MacDonald,Jean-Charles Cerottini,Vincenzo Cerundolo,Pedro Romero

View Articletitled, In Vivo Expression of Natural Killer Cell Inhibitory Receptors by Human Melanoma–Specific Cytolytic T Lymphocytes

Inhibition of T Helper Cell Type 2 Cell Differentiation and Immunoglobulin E Response by Ligand-Activated Vα14 Natural Killer T Cells

Junqing Cui,Naohiro Watanabe,Tetsu Kawano,Masakatsu Yamashita,Tohru Kamata,Chiori Shimizu,Motoko Kimura,Eiko Shimizu,Jyunzo Koike,Haruhiko Koseki,Yujiro Tanaka,Masaru Taniguchi,Toshinori Nakayama

View Articletitled, Inhibition of T Helper Cell Type 2 Cell Differentiation and Immunoglobulin E Response by Ligand-Activated Vα14 Natural Killer T Cells

Identification and Molecular Cloning of P75/Airm1, a Novel Member of the Sialoadhesin Family That Functions as an Inhibitory Receptor in Human Natural Killer Cells

Michela Falco,Roberto Biassoni,Cristina Bottino,Massimo Vitale,Simona Sivori,Raffaella Augugliaro,Lorenzo Moretta,Alessandro Moretta

View Articletitled, Identification and Molecular Cloning of P75/Airm1, a Novel Member of the Sialoadhesin Family That Functions as an Inhibitory Receptor in Human Natural Killer Cells

The Glycoprotein Ib-IX-V Complex Is a Platelet Counterreceptor for P-Selectin

Gabriel M. Romo,Jing-Fei Dong,Alicia J. Schade,Elizabeth E. Gardiner,Geoffrey S. Kansas,Chester Q. Li,Larry V. McIntire,Michael C. Berndt,José A. López

View Articletitled, The Glycoprotein Ib-IX-V Complex Is a Platelet Counterreceptor for P-Selectin

Cleavage by Granzyme B Is Strongly Predictive of Autoantigen Status: Implications for Initiation of Autoimmunity

Livia Casciola-Rosen,Felipe Andrade,Danielle Ulanet,Wes Bang Wong,Antony Rosen

View Articletitled, Cleavage by Granzyme B Is Strongly Predictive of Autoantigen Status: Implications for Initiation of Autoimmunity

Induction of B Cell Hyperplasia in Simian Immunodeficiency Virus–Infected Rhesus Macaques with the Simian Homologue of Kaposi's Sarcoma–Associated Herpesvirus

Scott W. Wong,Eric P. Bergquam,Ryan M. Swanson,Felix W. Lee,Stanley M. Shiigi,Nancy A. Avery,John W. Fanton,Michael K. Axthelm

View Articletitled, Induction of B Cell Hyperplasia in Simian Immunodeficiency Virus–Infected Rhesus Macaques with the Simian Homologue of Kaposi's Sarcoma–Associated Herpesvirus

Viral Dynamics of Acute HIV-1 Infection

Susan J. Little,Angela R. McLean,Celsa A. Spina,Douglas D. Richman,Diane V. Havlir

View Articletitled, Viral Dynamics of Acute HIV-1 Infection

A Member of the Dendritic Cell Family That Enters B Cell Follicles and Stimulates Primary Antibody Responses Identified by a Mannose Receptor Fusion Protein

Claude Berney,Suzanne Herren,Christine A. Power,Siamon Gordon,Luisa Martinez-Pomares,Marie H. Kosco-Vilbois

View Articletitled, A Member of the Dendritic Cell Family That Enters B Cell Follicles and Stimulates Primary Antibody Responses Identified by a Mannose Receptor Fusion Protein

Macrophage and Retinal Pigment Epithelium Phagocytosis: Apoptotic Cells and Photoreceptors Compete for αvβ3 and αvβ5 Integrins, and Protein Kinase C Regulates αvβ5 Binding and Cytoskeletal Linkage

Silvia C. Finnemann,Enrique Rodriguez-Boulan

View Articletitled, Macrophage and Retinal Pigment Epithelium Phagocytosis: Apoptotic Cells and Photoreceptors Compete for αvβ3 and αvβ5 Integrins, and Protein Kinase C Regulates αvβ5 Binding and Cytoskeletal Linkage

Brief Definitive Report

Idiopathic Pulmonary Alveolar Proteinosis as an Autoimmune Disease with Neutralizing Antibody against Granulocyte/Macrophage Colony-Stimulating Factor

Takayuki Kitamura,Naohiko Tanaka,Junichi Watanabe,Uchida,Shiro Kanegasaki,Yoshitsugu Yamada,Koh Nakata

View Articletitled, Idiopathic Pulmonary Alveolar Proteinosis as an Autoimmune Disease with Neutralizing Antibody against Granulocyte/Macrophage Colony-Stimulating Factor

Development of Cd8α/α and Cd8α/β T Cells in Major Histocompatibility Complex Class I–Deficient Mice

Gobardhan Das,Charles A. Janeway, Jr.

View Articletitled, Development of Cd8α/α and Cd8α/β T Cells in Major Histocompatibility Complex Class I–Deficient Mice

Selection and Expansion of CD8α/α¹ T Cell Receptor α/β¹ Intestinal Intraepithelial Lymphocytes in the Absence of Both Classical Major Histocompatibility Complex Class I and Nonclassical Cd1 Molecules

Se-Ho Park,Delphine Guy-Grand,François A. Lemonnier,Chyung-Ru Wang,Albert Bendelac,Bana Jabri

View Articletitled, Selection and Expansion of CD8α/α1 T Cell Receptor α/β1 Intestinal Intraepithelial Lymphocytes in the Absence of Both Classical Major Histocompatibility Complex Class I and Nonclassical Cd1 Molecules

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A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity

Cellular senescence: Neither irreversible nor reversible

Identification of α-galactosylceramide as an endogenous mammalian antigen for iNKT cells

Cancer Focus
CAR-T cell manufacturing: Major process parameters and next-generation strategies

Hypoxia is linked to acquired resistance to immune checkpoint inhibitors in lung cancer

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