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Journal Articles

Natural history of MZ B cells

David Nemazee

J Exp Med (2021) 218 (4): e20202700.

https://doi.org/10.1084/jem.20202700

Published: 08 February 2021

View article titled, Natural history of MZ B cells

Journal Articles

Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes

In Special Collection:

Vaccines: HIV and Beyond

Tara Bancroft, Blair L. DeBuysscher, Connor Weidle, Allison Schwartz, Abigail Wall, Matthew D. Gray, Junli Feng, Holly R. Steach, Kristin S. Fitzpatrick, Mesfin M. Gewe, Patrick D. Skog, Colleen Doyle-Cooper, Takayuki Ota, Roland K. Strong, David Nemazee, Marie Pancera, Leonidas Stamatatos, Andrew T. McGuire, Justin J. Taylor

J Exp Med (2019) 216 (10): 2331–2347.

https://doi.org/10.1084/jem.20190164

Published: 25 July 2019

View article titled, Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes

Includes: Supplementary data

Journal Articles

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo

In Special Collection:

B Cells, T Cells, Vaccines 2019

J Exp Med (2017) 214 (9): 2573–2590.

https://doi.org/10.1084/jem.20161160

Published: 28 August 2017

View article titled, Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo

Includes: Supplementary data

Journal Articles

Receptor editing and genetic variability in human autoreactive B cells

Julie Lang, Takayuki Ota, Margot Kelly, Pamela Strauch, Brian M. Freed, Raul M. Torres, David Nemazee, Roberta Pelanda

J Exp Med (2015) 213 (1): 93–108.

https://doi.org/10.1084/jem.20151039

Published: 22 December 2015

View article titled, Receptor editing and genetic variability in human autoreactive B cells

Journal Articles

Liver-expressed Igκ superantigen induces tolerance of polyclonal B cells by clonal deletion not κ to λ receptor editing

Takayuki Ota, Miyo Ota, Bao Hoa Duong, Amanda L. Gavin, David Nemazee

J Exp Med (2011) 208 (3): 617–629.

https://doi.org/10.1084/jem.20102265

Published: 28 February 2011

View article titled, Liver-expressed Igκ superantigen induces tolerance of polyclonal B cells by clonal deletion not κ to λ receptor editing

Includes: Supplementary data

Journal Articles

Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo

Bao Hoa Duong, Hua Tian, Takayuki Ota, Gladys Completo, Shoufa Han, José Luis Vela, Miyo Ota, Michael Kubitz, Nicolai Bovin, James C. Paulson, David Nemazee

J Exp Med (2010) 207 (2): 445.

https://doi.org/10.1084/jem.2009187312910c

Published: 08 February 2010

View article titled, Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo

Journal Articles

Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo

Bao Hoa Duong, Hua Tian, Takayuki Ota, Gladys Completo, Shoufa Han, José Luis Vela, Miyo Ota, Michael Kubitz, Nicolai Bovin, James C. Paulson, David Nemazee

J Exp Med (2009) 207 (1): 173–187.

https://doi.org/10.1084/jem.20091873

Published: 28 December 2009

View article titled, Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo

Includes: Supplementary data

Journal Articles

Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci

Kristina Beck, Mandy M. Peak, Takayuki Ota, David Nemazee, Cornelis Murre

J Exp Med (2009) 206 (10): 2271–2284.

https://doi.org/10.1084/jem.20090756

Published: 14 September 2009

View article titled, Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci

Includes: Supplementary data

Journal Articles

Reduced receptor editing in lupus-prone MRL/lpr mice

Jennifer L. Lamoureux, Lisa C. Watson, Marie Cherrier, Patrick Skog, David Nemazee, Ann J. Feeney

J Exp Med (2007) 204 (12): 2853–2864.

https://doi.org/10.1084/jem.20071268

Published: 29 October 2007

View article titled, Reduced receptor editing in lupus-prone MRL/lpr mice

Journal Articles

An immunoglobulin Cκ-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system

Djemel Ait-Azzouzene, Laurent Verkoczy, Jorieke Peters, Amanda Gavin, Patrick Skog, José Luis Vela, David Nemazee

J Exp Med (2005) 201 (5): 817–828.

https://doi.org/10.1084/jem.20041854

Published: 28 February 2005

View article titled, An immunoglobulin Cκ-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system

Journal Articles

Receptor Editing and Marginal Zone B Cell Development Are Regulated by the Helix-Loop-Helix Protein, E2A

Melanie W. Quong, Annica Martensson, Anton W. Langerak, Richard R. Rivera, David Nemazee, Cornelis Murre

J Exp Med (2004) 199 (8): 1101–1112.

https://doi.org/10.1084/jem.20031180

Published: 12 April 2004

View article titled, Receptor Editing and Marginal Zone B Cell Development Are Regulated by the Helix-Loop-Helix Protein, E2A

Journal Articles

Visualization of the Genesis and Fate of Isotype-switched B Cells during a Primary Immune Response

Kathryn A. Pape, Valerie Kouskoff, David Nemazee, H. Lucy Tang, Jason G. Cyster, Lina E. Tze, Keli L. Hippen, Timothy W. Behrens, Marc K. Jenkins

J Exp Med (2003) 197 (12): 1677–1687.

https://doi.org/10.1084/jem.20012065

Published: 09 June 2003

View article titled, Visualization of the Genesis and Fate of Isotype-switched B Cells during a Primary Immune Response

Journal Articles

Revising B Cell Receptors

David Nemazee, Martin Weigert

J Exp Med (2000) 191 (11): 1813–1818.

https://doi.org/10.1084/jem.191.11.1813

Published: 30 May 2000

View article titled, Revising B Cell Receptors

Journal Articles

Distinct Signal Thresholds for the Unique Antigen Receptor–Linked Gene Expression Programs in Mature and Immature B Cells

Robert J. Benschop, Doron Melamed, David Nemazee, John C. Cambier

J Exp Med (1999) 190 (6): 749–756.

https://doi.org/10.1084/jem.190.6.749

Published: 20 September 1999

View article titled, Distinct Signal Thresholds for the Unique Antigen Receptor–Linked Gene Expression Programs in Mature and Immature B Cells

Journal Articles

Antigens Varying in Affinity for the B Cell Receptor Induce Differential B Lymphocyte Responses

Valerie Kouskoff, Sara Famiglietti, Georges Lacaud, Paul Lang, James E. Rider, Brian K. Kay, John C. Cambier, David Nemazee

J Exp Med (1998) 188 (8): 1453–1464.

https://doi.org/10.1084/jem.188.8.1453

Published: 19 October 1998

View article titled, Antigens Varying in Affinity for the B Cell Receptor Induce Differential B Lymphocyte Responses

Journal Articles

Receptor Editing Occurs Frequently during Normal B Cell Development

Marc W. Retter, David Nemazee

J Exp Med (1998) 188 (7): 1231–1238.

https://doi.org/10.1084/jem.188.7.1231

Published: 05 October 1998

View article titled, Receptor Editing Occurs Frequently during Normal B Cell Development

Journal Articles

Efficient Peripheral Clonal Elimination of B Lymphocytes in MRL/lpr Mice Bearing Autoantibody Transgenes

Jennifer A. Kench, David M. Russell, David Nemazee

J Exp Med (1998) 188 (5): 909–917.

https://doi.org/10.1084/jem.188.5.909

Published: 07 September 1998

View article titled, Efficient Peripheral Clonal Elimination of B Lymphocytes in MRL/<em>lpr</em> Mice Bearing Autoantibody Transgenes

Journal Articles

Enforced Bcl-2 Expression Inhibits Antigen-mediated Clonal Elimination of Peripheral B Cells in an Antigen Dose–dependent Manner and Promotes Receptor Editing in Autoreactive, Immature B Cells

Julie Lang, B. Arnold, G. Hammerling, Alan W. Harris, Stanley Korsmeyer, David Russell, Andreas Strasser, David Nemazee

J Exp Med (1997) 186 (9): 1513–1522.

https://doi.org/10.1084/jem.186.9.1513

Published: 03 November 1997

View article titled, Enforced Bcl-2 Expression Inhibits Antigen-mediated Clonal Elimination of Peripheral B Cells in an Antigen Dose–dependent Manner and Promotes Receptor Editing in Autoreactive, Immature B Cells

NARROW

Natural history of MZ B cells

Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo

Receptor editing and genetic variability in human autoreactive B cells

Liver-expressed Igκ superantigen induces tolerance of polyclonal B cells by clonal deletion not κ to λ receptor editing

Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo

Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo

Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci

Reduced receptor editing in lupus-prone MRL/lpr mice

An immunoglobulin Cκ-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system

Receptor Editing and Marginal Zone B Cell Development Are Regulated by the Helix-Loop-Helix Protein, E2A

Visualization of the Genesis and Fate of Isotype-switched B Cells during a Primary Immune Response

Revising B Cell Receptors

Distinct Signal Thresholds for the Unique Antigen Receptor–Linked Gene Expression Programs in Mature and Immature B Cells

Antigens Varying in Affinity for the B Cell Receptor Induce Differential B Lymphocyte Responses

Receptor Editing Occurs Frequently during Normal B Cell Development

Efficient Peripheral Clonal Elimination of B Lymphocytes in MRL/lpr Mice Bearing Autoantibody Transgenes

Enforced Bcl-2 Expression Inhibits Antigen-mediated Clonal Elimination of Peripheral B Cells in an Antigen Dose–dependent Manner and Promotes Receptor Editing in Autoreactive, Immature B Cells

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