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An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins.
J C Skipper,R C Hendrickson,P H Gulden,V Brichard,A Van Pel,Y Chen,J Shabanowitz,T Wolfel,C L Slingluff, Jr,T Boon,D F Hunt,V H Engelhard
Dissection of immunoglobulin E and T lymphocyte reactivity of isoforms of the major birch pollen allergen Bet v 1: potential use of hypoallergenic isoforms for immunotherapy.
F Ferreira,K Hirtenlehner,A Jilek,J Godnik-Cvar,H Breiteneder,R Grimm,K Hoffmann-Sommergruber,O Scheiner,D Kraft,M Breitenbach,H J Rheinberger,C Ebner
The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.
Tumor necrosis factor alpha is a potent synergistic factor for the proliferation of primitive human hematopoietic progenitor cells and induces resistance to transforming growth factor beta but not to interferon gamma.