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Journal Articles

Myeloid-targeting immunotherapies overcome inhibitory barriers in immune-evasive neuroblastoma

In Special Collection:
Macrophages and Dendritic Cells in Health and Disease
Marie Ménard, Hiroyuki Yoda, Nicole Nasholm, Megumi J. Barata, Linyu Wang, Erin F. Simonds, Edbert D. Lu, Shannon Wong-Michalak, Lauren McHenry, Alvin Farrel, Rebecca Kaufman, Vanessa Lopez, Rebekah J. Kennedy, G. Esteban Fernandez, Hiroyuki Shimada, Liron D. Grossmann, Shahab Asgharzadeh, John M. Maris, W. Clay Gustafson, William A. Weiss
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20231417.
https://doi.org/10.1084/jem.20231417
Published: 14 July 2025
View article titled, Myeloid-targeting immunotherapies overcome inhibitory barriers in immune-evasive neuroblastoma
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Includes: Supplementary data
Journal Articles

Large-scale mutational analysis identifies UNC93B1 variants that drive TLR-mediated autoimmunity in mice and humans

In Special Collection:
JEM Clinical Immunology Collection 2024 , Cytokines Collection 2024 , Genes and Immunity , Immunology Update Winter 2025
Victoria E. Rael, Julian A. Yano, John P. Huizar, Leianna C. Slayden, Madeleine A. Weiss, Elizabeth A. Turcotte, Jacob M. Terry, Wenqi Zuo, Isabelle Thiffault, Tomi Pastinen, Emily G. Farrow, Janda L. Jenkins, Mara L. Becker, Stephen C. Wong, Anne M. Stevens, Catherine Otten, Eric J. Allenspach, Devon E. Bonner, Jonathan A. Bernstein, Matthew T. Wheeler, Robert A. Saxton, Undiagnosed Diseases Network, Bo Liu, Olivia Majer, Gregory M. Barton
Journal: Journal of Experimental Medicine
J Exp Med (2024) 221 (8): e20232005.
https://doi.org/10.1084/jem.20232005
Published: 23 May 2024
View article titled, Large-scale mutational analysis identifies UNC93B1 variants that drive TLR-mediated autoimmunity in mice and humans
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Includes: Supplementary data
Journal Articles

All eyes on a phosphatase in glioma stem cells

Robert A. Lindquist, William A. Weiss
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (11): e20211605.
https://doi.org/10.1084/jem.20211605
Published: 12 October 2021
View article titled, All eyes on a phosphatase in glioma stem cells
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Journal Articles

A SHHecret target of relapsed medulloblastoma: Astrocytes

Zulekha A. Qadeer, William A. Weiss
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (9): e20211141.
https://doi.org/10.1084/jem.20211141
Published: 16 August 2021
View article titled, A SHHecret target of relapsed medulloblastoma: Astrocytes
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Journal Articles

Neutrophils instruct homeostatic and pathological states in naive tissues

In Special Collection:
2018: The Year in Experimental Medicine , Myeloid Cells 2019
Maria Casanova-Acebes, José A. Nicolás-Ávila, Jackson LiangYao Li, Susana García-Silva, Akhila Balachander, Andrea Rubio-Ponce, Linnea A. Weiss, José M. Adrover, Kyle Burrows, Noelia A-González, Ivan Ballesteros, Sapna Devi, Juan A. Quintana, Georgiana Crainiciuc, Magdalena Leiva, Matthias Gunzer, Christian Weber, Takashi Nagasawa, Oliver Soehnlein, Miriam Merad, Arthur Mortha, Lai Guan Ng, Hector Peinado, Andrés Hidalgo
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (11): 2778–2795.
https://doi.org/10.1084/jem.20181468
Published: 03 October 2018
View article titled, Neutrophils instruct homeostatic and pathological states in naive tissues
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Includes: Supplementary data
Journal Articles

Neutralizing antibodies to HIV-1 induced by immunization

Laura E. McCoy, Robin A. Weiss
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (2): 209–223.
https://doi.org/10.1084/jem.20121827
Published: 11 February 2013
View article titled, Neutralizing antibodies to HIV-1 induced by immunization
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Journal Articles

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization

Laura E. McCoy, Anna Forsman Quigley, Nika M. Strokappe, Bianca Bulmer-Thomas, Michael S. Seaman, Daniella Mortier, Lucy Rutten, Nikita Chander, Carolyn J. Edwards, Robin Ketteler, David Davis, Theo Verrips, Robin A. Weiss
Journal: Journal of Experimental Medicine
J Exp Med (2012) 209 (6): 1091–1103.
https://doi.org/10.1084/jem.20112655
Published: 28 May 2012
View article titled, Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization
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Includes: Supplementary data
Journal Articles

100 years of Rous sarcoma virus

Robin A. Weiss, Peter K. Vogt
Journal: Journal of Experimental Medicine
J Exp Med (2011) 208 (12): 2351–2355.
https://doi.org/10.1084/jem.20112160
Published: 21 November 2011
View article titled, 100 years of Rous sarcoma virus
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Journal Articles

Reconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene.

N Taylor, K B Bacon, S Smith, T Jahn, T A Kadlecek, L Uribe, D B Kohn, E W Gelfand, A Weiss, K Weinberg
Journal: Journal of Experimental Medicine
J Exp Med (1996) 184 (5): 2031–2036.
https://doi.org/10.1084/jem.184.5.2031
Published: 01 November 1996
View article titled, Reconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene.
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Journal Articles

c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1.

V S Shapiro, M N Mollenauer, W C Greene, A Weiss
Journal: Journal of Experimental Medicine
J Exp Med (1996) 184 (5): 1663–1669.
https://doi.org/10.1084/jem.184.5.1663
Published: 01 November 1996
View article titled, c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1.
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Journal Articles

Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C.

A M Fry, L L Lanier, A Weiss
Journal: Journal of Experimental Medicine
J Exp Med (1996) 184 (1): 295–300.
https://doi.org/10.1084/jem.184.1.295
Published: 01 July 1996
View article titled, Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C.
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Journal Articles

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes.

N S van Oers, N Killeen, A Weiss
Journal: Journal of Experimental Medicine
J Exp Med (1996) 183 (3): 1053–1062.
https://doi.org/10.1084/jem.183.3.1053
Published: 01 March 1996
View article titled, Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes.
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Journal Articles

Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling.

D Qian, M N Mollenauer, A Weiss
Journal: Journal of Experimental Medicine
J Exp Med (1996) 183 (2): 611–620.
https://doi.org/10.1084/jem.183.2.611
Published: 01 February 1996
View article titled, Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling.
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Journal Articles

The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-zeta subunit.

N S van Oers, H von Boehmer, A Weiss
Journal: Journal of Experimental Medicine
J Exp Med (1995) 182 (5): 1585–1590.
https://doi.org/10.1084/jem.182.5.1585
Published: 01 November 1995
View article titled, The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-zeta subunit.
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Journal Articles

Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes.

E W Gelfand, K Weinberg, B D Mazer, T A Kadlecek, A Weiss
Journal: Journal of Experimental Medicine
J Exp Med (1995) 182 (4): 1057–1065.
https://doi.org/10.1084/jem.182.4.1057
Published: 01 October 1995
View article titled, Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes.
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Journal Articles

In vivo sequestration of Plasmodium falciparum-infected human erythrocytes: a severe combined immunodeficiency mouse model for cerebral malaria.

K Willimann, H Matile, N A Weiss, B A Imhof
Journal: Journal of Experimental Medicine
J Exp Med (1995) 182 (3): 643–653.
https://doi.org/10.1084/jem.182.3.643
Published: 01 September 1995
View article titled, In vivo sequestration of Plasmodium falciparum-infected human erythrocytes: a severe combined immunodeficiency mouse model for cerebral malaria.
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Journal Articles

T cells reactive to an inducible heat shock protein induce disease in toxin-induced interstitial nephritis.

R A Weiss, M P Madaio, J E Tomaszewski, C J Kelly
Journal: Journal of Experimental Medicine
J Exp Med (1994) 180 (6): 2239–2250.
https://doi.org/10.1084/jem.180.6.2239
Published: 01 December 1994
View article titled, T cells reactive to an inducible heat shock protein induce disease in toxin-induced interstitial nephritis.
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Journal Articles

The CD3 chains of the T cell antigen receptor associate with the ZAP-70 tyrosine kinase and are tyrosine phosphorylated after receptor stimulation.

D B Straus, A Weiss
Journal: Journal of Experimental Medicine
J Exp Med (1993) 178 (5): 1523–1530.
https://doi.org/10.1084/jem.178.5.1523
Published: 01 November 1993
View article titled, The CD3 chains of the T cell antigen receptor associate with the ZAP-70 tyrosine kinase and are tyrosine phosphorylated after receptor stimulation.
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Journal Articles

Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain.

B A Irving, A C Chan, A Weiss
Journal: Journal of Experimental Medicine
J Exp Med (1993) 177 (4): 1093–1103.
https://doi.org/10.1084/jem.177.4.1093
Published: 01 April 1993
View article titled, Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain.
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Journal Articles

CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation.

J D Fraser, M E Newton, A Weiss
Journal: Journal of Experimental Medicine
J Exp Med (1992) 175 (4): 1131–1134.
https://doi.org/10.1084/jem.175.4.1131
Published: 01 April 1992
View article titled, CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation.
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