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The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.

D Pende, R Biassoni, C Cantoni, S Verdiani, M Falco, C di Donato, L Accame, C Bottino, A Moretta, L Moretta

J Exp Med (1996) 184 (2): 505–518.

https://doi.org/10.1084/jem.184.2.505

Published: 01 August 1996

View article titled, The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.

Journal Articles

The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

R Biassoni, C Cantoni, M Falco, S Verdiani, C Bottino, M Vitale, R Conte, A Poggi, A Moretta, L Moretta

J Exp Med (1996) 183 (2): 645–650.

https://doi.org/10.1084/jem.183.2.645

Published: 01 February 1996

View article titled, The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

Journal Articles

Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.

A Moretta, S Sivori, M Vitale, D Pende, L Morelli, R Augugliaro, C Bottino, L Moretta

J Exp Med (1995) 182 (3): 875–884.

https://doi.org/10.1084/jem.182.3.875

Published: 01 September 1995

View article titled, Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.

Journal Articles

Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones.

R Biassoni, M Falco, A Cambiaggi, P Costa, S Verdiani, D Pende, R Conte, C Di Donato, P Parham, L Moretta

J Exp Med (1995) 182 (2): 605–609.

https://doi.org/10.1084/jem.182.2.605

Published: 01 August 1995

View article titled, Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones.

Journal Articles

Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.

A Moretta, M Vitale, S Sivori, C Bottino, L Morelli, R Augugliaro, M Barbaresi, D Pende, E Ciccone, M Lopez-Botet, L Moretta

J Exp Med (1994) 180 (2): 545–555.

https://doi.org/10.1084/jem.180.2.545

Published: 01 August 1994

View article titled, Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.

Journal Articles

Human natural killer (NK) alloreactivity and its association with the major histocompatibility complex: ancestral haplotypes encode particular NK-defined haplotypes.

F T Christiansen, C S Witt, E Ciccone, D Townend, D Pende, D Viale, L J Abraham, R L Dawkins, L Moretta

J Exp Med (1993) 178 (3): 1033–1039.

https://doi.org/10.1084/jem.178.3.1033

Published: 01 September 1993

View article titled, Human natural killer (NK) alloreactivity and its association with the major histocompatibility complex: ancestral haplotypes encode particular NK-defined haplotypes.

Journal Articles

Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements.

M S Malnati, P Lusso, E Ciccone, A Moretta, L Moretta, E O Long

J Exp Med (1993) 178 (3): 961–969.

https://doi.org/10.1084/jem.178.3.961

Published: 01 September 1993

View article titled, Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements.

Journal Articles

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

A Moretta, M Vitale, C Bottino, A M Orengo, L Morelli, R Augugliaro, M Barbaresi, E Ciccone, L Moretta

J Exp Med (1993) 178 (2): 597–604.

https://doi.org/10.1084/jem.178.2.597

Published: 01 August 1993

View article titled, P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

Journal Articles

Regulation of hematopoiesis in vitro by alloreactive natural killer cell clones.

G Bellone, N M Valiante, O Viale, E Ciccone, L Moretta, G Trinchieri

J Exp Med (1993) 177 (4): 1117–1125.

https://doi.org/10.1084/jem.177.4.1117

Published: 01 April 1993

View article titled, Regulation of hematopoiesis in vitro by alloreactive natural killer cell clones.

Journal Articles

Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans.

E Ciccone, D Pende, O Viale, C Di Donato, G Tripodi, A M Orengo, J Guardiola, A Moretta, L Moretta

J Exp Med (1992) 175 (3): 709–718.

https://doi.org/10.1084/jem.175.3.709

Published: 01 March 1992

View article titled, Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans.

Journal Articles

CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta.

A Moretta, A Poggi, D Pende, G Tripodi, A M Orengo, N Pella, R Augugliaro, C Bottino, E Ciccone, L Moretta

J Exp Med (1991) 174 (6): 1393–1398.

https://doi.org/10.1084/jem.174.6.1393

Published: 01 December 1991

View article titled, CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta.

Journal Articles

In vitro proliferation and cloning of CD3- CD16+ cells from human thymocyte precursors.

M C Mingari, A Poggi, R Biassoni, R Bellomo, E Ciccone, N Pella, L Morelli, S Verdiani, A Moretta, L Moretta

J Exp Med (1991) 174 (1): 21–26.

https://doi.org/10.1084/jem.174.1.21

Published: 01 July 1991

View article titled, In vitro proliferation and cloning of CD3- CD16+ cells from human thymocyte precursors.

Journal Articles

In vitro expansion of CD3/TCR- human thymocyte populations that selectively lack CD3 delta gene expression: a phenotypic and functional analysis.

A Poggi, R Biassoni, N Pella, F Paolieri, R Bellomo, A Bertolini, L Moretta, M C Mingari

J Exp Med (1990) 172 (5): 1409–1418.

https://doi.org/10.1084/jem.172.5.1409

Published: 01 November 1990

View article titled, In vitro expansion of CD3/TCR- human thymocyte populations that selectively lack CD3 delta gene expression: a phenotypic and functional analysis.

Journal Articles

Specific recognition of human CD3-CD16+ natural killer cells requires the expression of an autosomic recessive gene on target cells.

E Ciccone, D Pende, O Viale, G Tambussi, S Ferrini, R Biassoni, A Longo, J Guardiola, A Moretta, L Moretta

J Exp Med (1990) 172 (1): 47–52.

https://doi.org/10.1084/jem.172.1.47

Published: 01 July 1990

View article titled, Specific recognition of human CD3-CD16+ natural killer cells requires the expression of an autosomic recessive gene on target cells.

Journal Articles

A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.

A Moretta, G Tambussi, C Bottino, G Tripodi, A Merli, E Ciccone, G Pantaleo, L Moretta

J Exp Med (1990) 171 (3): 695–714.

https://doi.org/10.1084/jem.171.3.695

Published: 01 March 1990

View article titled, A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.

Journal Articles

Diversity and structure of human T cell receptor delta chain genes in peripheral blood gamma/delta-bearing T lymphocytes.

Y Takihara, J Reimann, E Michalopoulos, E Ciccone, L Moretta, T W Mak

J Exp Med (1989) 169 (2): 393–405.

https://doi.org/10.1084/jem.169.2.393

Published: 01 February 1989

View article titled, Diversity and structure of human T cell receptor delta chain genes in peripheral blood gamma/delta-bearing T lymphocytes.

Journal Articles

Specific lysis of allogeneic cells after activation of CD3- lymphocytes in mixed lymphocyte culture.

E Ciccone, O Viale, D Pende, M Malnati, R Biassoni, G Melioli, A Moretta, E O Long, L Moretta

J Exp Med (1988) 168 (6): 2403–2408.

https://doi.org/10.1084/jem.168.6.2403

Published: 01 December 1988

View article titled, Specific lysis of allogeneic cells after activation of CD3- lymphocytes in mixed lymphocyte culture.

Journal Articles

Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor.

C Bottino, G Tambussi, S Ferrini, E Ciccone, P Varese, M C Mingari, L Moretta, A Moretta

J Exp Med (1988) 168 (2): 491–505.

https://doi.org/10.1084/jem.168.2.491

Published: 01 August 1988

View article titled, Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor.

Journal Articles

A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s).

E Ciccone, S Ferrini, C Bottino, O Viale, I Prigione, G Pantaleo, G Tambussi, A Moretta, L Moretta

J Exp Med (1988) 168 (1): 1–11.

https://doi.org/10.1084/jem.168.1.1

Published: 01 July 1988

View article titled, A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s).

Journal Articles

Human cytolytic cell clones lacking surface expression of T cell receptor alpha/beta or gamma/delta. Evidence that surface structures other than CD3 or CD2 molecules are required for signal transduction.

G Pantaleo, M R Zocchi, S Ferrini, A Poggi, G Tambussi, C Bottino, L Moretta, A Moretta

J Exp Med (1988) 168 (1): 13–24.

https://doi.org/10.1084/jem.168.1.13

Published: 01 July 1988

View article titled, Human cytolytic cell clones lacking surface expression of T cell receptor alpha/beta or gamma/delta. Evidence that surface structures other than CD3 or CD2 molecules are required for signal transduction.

NARROW

The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.

The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.

Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones.

Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.

Human natural killer (NK) alloreactivity and its association with the major histocompatibility complex: ancestral haplotypes encode particular NK-defined haplotypes.

Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements.

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

Regulation of hematopoiesis in vitro by alloreactive natural killer cell clones.

Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans.

CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta.

In vitro proliferation and cloning of CD3- CD16+ cells from human thymocyte precursors.

In vitro expansion of CD3/TCR- human thymocyte populations that selectively lack CD3 delta gene expression: a phenotypic and functional analysis.

Specific recognition of human CD3-CD16+ natural killer cells requires the expression of an autosomic recessive gene on target cells.

A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.

Diversity and structure of human T cell receptor delta chain genes in peripheral blood gamma/delta-bearing T lymphocytes.

Specific lysis of allogeneic cells after activation of CD3- lymphocytes in mixed lymphocyte culture.

Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor.

A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s).

Human cytolytic cell clones lacking surface expression of T cell receptor alpha/beta or gamma/delta. Evidence that surface structures other than CD3 or CD2 molecules are required for signal transduction.

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