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Journal Articles

Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production

In Special Collection:
Hematology and Stem Cells 2023
Yoon-A Kang, Hyojung Paik, Si Yi Zhang, Jonathan J. Chen, Oakley C. Olson, Carl A. Mitchell, Amelie Collins, James W. Swann, Matthew R. Warr, Rong Fan, Emmanuelle Passegué
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20230088.
https://doi.org/10.1084/jem.20230088
Published: 26 April 2023
View articletitled, Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production
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Includes: Supplementary data
Journal Articles

TBK1 recruitment to STING mediates autoinflammatory arthritis caused by defective DNA clearance

Tong Li, Seoyun Yum, Minghao Li, Xiang Chen, Xiaoxia Zuo, Zhijian J. Chen
Journal: Journal of Experimental Medicine
J Exp Med (2021) 219 (1): e20211539.
https://doi.org/10.1084/jem.20211539
Published: 13 December 2021
View articletitled, TBK1 recruitment to STING mediates autoinflammatory arthritis caused by defective DNA clearance
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Journal Articles

The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer

In Special Collection:
Cytokines 2018 , Innate Immune Sensors in Health and Disease , JEM Cancer Collection 2019 , JEM Reviews Collection , Scientific and Technical Advances in Cancer Immunology 2019
Tuo Li, Zhijian J. Chen
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (5): 1287–1299.
https://doi.org/10.1084/jem.20180139
Published: 05 April 2018
View articletitled, The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer
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Journal Articles

TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects

Min-Kyung Choo, Yasuyo Sano, Changhoon Kim, Kei Yasuda, Xiao-Dong Li, Xin Lin, Mary Stenzel-Poore, Lena Alexopoulou, Sankar Ghosh, Eicke Latz, Ian R. Rifkin, Zhijian J. Chen, George C. Stewart, Hyonyong Chong, Jin Mo Park
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (5): 1297–1311.
https://doi.org/10.1084/jem.20161141
Published: 11 April 2017
View articletitled, TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects
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Journal Articles

Flow-induced protein kinase A–CREB pathway acts via BMP signaling to promote HSC emergence

Peter Geon Kim, Haruko Nakano, Partha P. Das, Michael J. Chen, R. Grant Rowe, Stephanie S. Chou, Samantha J. Ross, Kathleen M. Sakamoto, Leonard I. Zon, Thorsten M. Schlaeger, Stuart H. Orkin, Atsushi Nakano, George Q. Daley
Journal: Journal of Experimental Medicine
J Exp Med (2015) 212 (5): 633–648.
https://doi.org/10.1084/jem.20141514
Published: 13 April 2015
View articletitled, Flow-induced protein kinase A–CREB pathway acts via BMP signaling to promote HSC emergence
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Includes: Supplementary data
Journal Articles

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

Lili Jing, Owen J. Tamplin, Michael J. Chen, Qing Deng, Shenia Patterson, Peter G. Kim, Ellen M. Durand, Ashley McNeil, Julie M. Green, Shinobu Matsuura, Julien Ablain, Margot K. Brandt, Thorsten M. Schlaeger, Anna Huttenlocher, George Q. Daley, Katya Ravid, Leonard I. Zon
Journal: Journal of Experimental Medicine
J Exp Med (2015) 212 (5): 649–663.
https://doi.org/10.1084/jem.20141528
Published: 13 April 2015
View articletitled, Adenosine signaling promotes hematopoietic stem and progenitor cell emergence
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Includes: Supplementary data
Journal Articles

Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

Sarah L. Jongbloed, Andrew J. Kassianos, Kylie J. McDonald, Georgina J. Clark, Xinsheng Ju, Catherine E. Angel, Chun-Jen J. Chen, P. Rod Dunbar, Robert B. Wadley, Varinder Jeet, Annelie J.E. Vulink, Derek N.J. Hart, Kristen J. Radford
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (6): 1247–1260.
https://doi.org/10.1084/jem.20092140
Published: 17 May 2010
View articletitled, Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens
Open the PDF for Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens in another window
Includes: Supplementary data
Journal Articles

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP

Sarah M. McWhirter, Roman Barbalat, Kathryn M. Monroe, Mary F. Fontana, Mamoru Hyodo, Nathalie T. Joncker, Ken J. Ishii, Shizuo Akira, Marco Colonna, Zhijian J. Chen, Katherine A. Fitzgerald, Yoshihiro Hayakawa, Russell E. Vance
Journal: Journal of Experimental Medicine
J Exp Med (2009) 206 (9): 1899–1911.
https://doi.org/10.1084/jem.20082874
Published: 03 August 2009
View articletitled, A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
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Includes: Supplementary data
Journal Articles

Ku70 Is Required for DNA Repair but Not for T Cell Antigen Receptor Gene Recombination In Vivo

Honghai Ouyang, Andre Nussenzweig, Akihiro Kurimasa, Vera da Costa Soares, Xiaoling Li, Carlos Cordon-Cardo, Wen-hui Li, Nge Cheong, Michel Nussenzweig, George Iliakis, David J. Chen, Gloria C. Li
Journal: Journal of Experimental Medicine
J Exp Med (1997) 186 (6): 921–929.
https://doi.org/10.1084/jem.186.6.921
Published: 15 September 1997
View articletitled, Ku70 Is Required for DNA Repair but Not for T Cell Antigen Receptor Gene Recombination In Vivo
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Journal Articles

Interleukin-10 inhibits tumor metastasis through an NK cell-dependent mechanism.

L M Zheng, D M Ojcius, F Garaud, C Roth, E Maxwell, Z Li, H Rong, J Chen, X Y Wang, J J Catino, I King
Journal: Journal of Experimental Medicine
J Exp Med (1996) 184 (2): 579–584.
https://doi.org/10.1084/jem.184.2.579
Published: 01 August 1996
View articletitled, Interleukin-10 inhibits tumor metastasis through an NK cell-dependent mechanism.
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Journal Articles

T cell responses in calcineurin A alpha-deficient mice.

B W Zhang, G Zimmer, J Chen, D Ladd, E Li, F W Alt, G Wiederrecht, J Cryan, E A O'Neill, C E Seidman, A K Abbas, J G Seidman
Journal: Journal of Experimental Medicine
J Exp Med (1996) 183 (2): 413–420.
https://doi.org/10.1084/jem.183.2.413
Published: 01 February 1996
View articletitled, T cell responses in calcineurin A alpha-deficient mice.
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Journal Articles

T cells, but not B cells, are required for bowel inflammation in interleukin 2-deficient mice.

A Ma, M Datta, E Margosian, J Chen, I Horak
Journal: Journal of Experimental Medicine
J Exp Med (1995) 182 (5): 1567–1572.
https://doi.org/10.1084/jem.182.5.1567
Published: 01 November 1995
View articletitled, T cells, but not B cells, are required for bowel inflammation in interleukin 2-deficient mice.
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Journal Articles

CTLA-4 ligands are required to induce an in vivo interleukin 4 response to a gastrointestinal nematode parasite.

P Lu, X Zhou, S J Chen, M Moorman, S C Morris, F D Finkelman, P Linsley, J F Urban, W C Gause
Journal: Journal of Experimental Medicine
J Exp Med (1994) 180 (2): 693–698.
https://doi.org/10.1084/jem.180.2.693
Published: 01 August 1994
View articletitled, CTLA-4 ligands are required to induce an in vivo interleukin 4 response to a gastrointestinal nematode parasite.
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Journal Articles

Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice.

G Van Zant, B P Holland, P W Eldridge, J J Chen
Journal: Journal of Experimental Medicine
J Exp Med (1990) 171 (5): 1547–1565.
https://doi.org/10.1084/jem.171.5.1547
Published: 01 May 1990
View articletitled, Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice.
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