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In This Issue

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Article

Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells

In Special Collection: JCB65: Autophagy
Noboru Mizushima,Akitsugu Yamamoto,Masahiko Hatano,Yoshinori Kobayashi,Yukiko Kabeya,Kuninori Suzuki,Takeshi Tokuhisa,Yoshinori Ohsumi,Tamotsu Yoshimori
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Drosophila Aurora B Kinase Is Required for Histone H3 Phosphorylation and Condensin Recruitment during Chromosome Condensation and to Organize the Central Spindle during Cytokinesis

Régis Giet,David M. Glover
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Connection of the Mitochondrial Outer and Inner Membranes by Fzo1 Is Critical for Organellar Fusion

Stefan Fritz,Doron Rapaport,Elisabeth Klanner,Walter Neupert,Benedikt Westermann
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Stromelysin-1 Regulates Adipogenesis during Mammary Gland Involution

Caroline M. Alexander,Sushma Selvarajan,John Mudgett,Zena Werb
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Hsp70 and Antifibrillogenic Peptides Promote Degradation and Inhibit Intracellular Aggregation of Amyloidogenic Light Chains

Jeanne L. Dul,David P. Davis,Edward K. Williamson,Fred J. Stevens,Yair Argon
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A Specific Role of Phosphatidylinositol 3–Kinase γ: A Regulation of Autonomic Ca2+ Oscillations in Cardiac Cells

Claire Bony,Serge Roche,Ueno Shuichi,Takehiko Sasaki,Michael A. Crackower,Josef Penninger,Hiroyuki Mano,Michel Pucéat
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The Karyopherin Kap142p/Msn5p Mediates Nuclear Import and Nuclear Export of Different Cargo Proteins

Kimihisa Yoshida,Günter Blobel
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Plasminogen Activator Inhibitor 1 Functions as a Urokinase Response Modifier at the Level of Cell Signaling and Thereby Promotes Mcf-7 Cell Growth

Donna J. Webb,Keena S. Thomas,Steven L. Gonias
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Activation of Nuclear Factor κb and bcl-x Survival Gene Expression by Nerve Growth Factor Requires Tyrosine Phosphorylation of IκBα

Nguyen Truc Bui,Antonia Livolsi,Jean-Francois Peyron,Jochen H.M. Prehn
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A Novel 14-Kilodalton Protein Interacts with the Mitogen-Activated Protein Kinase Scaffold Mp1 on a Late Endosomal/Lysosomal Compartment

Winfried Wunderlich,Irene Fialka,David Teis,Arno Alpi,Andrea Pfeifer,Robert G. Parton,Friedrich Lottspeich,Lukas A. Huber
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The Plasminogen Activator Inhibitor PAI-1 Controls in Vivo Tumor Vascularization by Interaction with Proteases, Not Vitronectin: Implications for Antiangiogenic Strategies

Khalid Bajou,Véronique Masson,Robert D. Gerard,Petra M. Schmitt,Valérie Albert,Michael Praus,Leif R. Lund,Thomas L. Frandsen,Nils Brunner,Keld Dano,Norbert E. Fusenig,Ulrich Weidle,Geert Carmeliet,David Loskutoff,Desiré Collen,Peter Carmeliet,Jean Michel Foidart,Agnès Noël
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Presenilin 1 Negatively Regulates β-Catenin/T Cell Factor/Lymphoid Enhancer Factor-1 Signaling Independently of β-Amyloid Precursor Protein and Notch Processing

Salvador Soriano,David E. Kang,Maofu Fu,Richard Pestell,Nathalie Chevallier,Hui Zheng,Edward H. Koo
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Rab27a Regulates the Peripheral Distribution of Melanosomes in Melanocytes

In Special Collection: JCB65: Trafficking and Organelles
Alistair N. Hume,Lucy M. Collinson,Andrzej Rapak,Anita Q. Gomes,Colin R. Hopkins,Miguel C. Seabra
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Distinct Protein Sorting and Localization to Premelanosomes, Melanosomes, and Lysosomes in Pigmented Melanocytic Cells✪

Graça Raposo,Danielle Tenza,Diane M. Murphy,Joanne F. Berson,Michael S. Marks
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Rab27a Is Required for Regulated Secretion in Cytotoxic T Lymphocytes

In Special Collection: JCB65: Trafficking and Organelles
Jane C. Stinchcombe,Duarte C. Barral,Emilie H. Mules,Sarah Booth,Alistair N. Hume,Laura M. Machesky,Miguel C. Seabra,Gillian M. Griffiths
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Defective Granule Exocytosis in Rab27a-Deficient Lymphocytes from Ashen Mice

Elias K. Haddad,Xufeng Wu,John A. Hammer, III,Pierre A. Henkart
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Report

Rab27a: A Key to Melanosome Transport in Human Melanocytes

Philippe Bahadoran,Edith Aberdam,Frédéric Mantoux,Roser Buscà,Karine Bille,Nevin Yalman,Geneviève de Saint-Basile,Ricardo Casaroli-Marano,Jean-Paul Ortonne,Robert Ballotti
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An Essential Role for the Substrate-Binding Region of Hsp40s in Saccharomyces cerevisiae

Jill L. Johnson,Elizabeth A. Craig
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Review

Where Notch and WNT Signaling Meet: The Presenilin Hub

Bart De Strooper,Wim Annaert
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Of Yeast, Mice, and Men: Rab Proteins and Organelle Transport

Sean W. Deacon,Vladimir I. Gelfand
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