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Journal Articles

Piezo2 interacts with E-cadherin in specialized gastrointestinal epithelial mechanoreceptors

In Special Collection:
JGP Highlights Collection 2025
Arnaldo Mercado-Perez, Jeric P. Hernandez, Yaroslav Fedyshyn, Anthony J. Treichel, Vikram Joshi, Kimberlee Kossick, Kalpana R. Betageri, Gianrico Farrugia, Brooke Druliner, Arthur Beyder
Journal: Journal of General Physiology
J Gen Physiol (2024) 156 (12): e202213324.
https://doi.org/10.1085/jgp.202213324
Published: 04 November 2024
View article titled, Piezo2 interacts with E-cadherin in specialized gastrointestinal epithelial mechanoreceptors
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Journal Articles

Asymmetric contribution of a selectivity filter gate in triggering inactivation of CaV1.3 channels

Pedro J. del Rivero Morfin, Audrey L. Kochiss, Klaus R. Liedl, Bernhard E. Flucher, Monica L.I. Fernández-Quintero, Manu Ben-Johny
Journal: Journal of General Physiology
J Gen Physiol (2024) 156 (2): e202313365.
https://doi.org/10.1085/jgp.202313365
Published: 04 January 2024
View article titled, Asymmetric contribution of a selectivity filter gate in triggering inactivation of CaV1.3 channels
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Journal Articles

Elucidating molecular mechanisms of protoxin-II state-specific binding to the human NaV1.7 channel

Khoa Ngo, Diego Lopez Mateos, Yanxiao Han, Kyle C. Rouen, Surl-Hee Ahn, Heike Wulff, Colleen E. Clancy, Vladimir Yarov-Yarovoy, Igor Vorobyov
Journal: Journal of General Physiology
J Gen Physiol (2023) 156 (2): e202313368.
https://doi.org/10.1085/jgp.202313368
Published: 21 December 2023
View article titled, Elucidating molecular mechanisms of protoxin-II state-specific binding to the human NaV1.7 channel
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Includes: Supplementary data
Journal Articles

IP3R1 underlies diastolic ANO1 activation and pressure-dependent chronotropy in lymphatic collecting vessels

Scott D. Zawieja, Grace A. Pea, Sarah E. Broyhill, Advaya Patro, Karen H. Bromert, Min Li, Charles E. Norton, Jorge A. Castorena-Gonzalez, Edward J. Hancock, Christopher D. Bertram, Michael J. Davis
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (12): e202313358.
https://doi.org/10.1085/jgp.202313358
Published: 18 October 2023
View article titled, IP3R1 underlies diastolic ANO1 activation and pressure-dependent chronotropy in lymphatic collecting vessels
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Includes: Supplementary data
Journal Articles

A dual-clock-driven model of lymphatic muscle cell pacemaking to emulate knock-out of Ano1 or IP3R

Edward J. Hancock, Scott D. Zawieja, Charlie Macaskill, Michael J. Davis, Christopher D. Bertram
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (12): e202313355.
https://doi.org/10.1085/jgp.202313355
Published: 18 October 2023
View article titled, A dual-clock-driven model of lymphatic muscle cell pacemaking to emulate knock-out of Ano1 or IP3R
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Journal Articles

Disease-associated KCNMA1 variants decrease circadian clock robustness in channelopathy mouse models

In Special Collection:
Neuroscience Collection 2024
Ria L. Dinsdale, Cooper E. Roache, Andrea L. Meredith
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (11): e202313357.
https://doi.org/10.1085/jgp.202313357
Published: 20 September 2023
View article titled, Disease-associated KCNMA1 variants decrease circadian clock robustness in channelopathy mouse models
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Includes: Supplementary data
Journal Articles

Kv12 channels flick the switch

Ben Short
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202313459.
https://doi.org/10.1085/jgp.202313459
Published: 16 August 2023
View article titled, Kv12 channels flick the switch
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Journal Articles

Cold and warmth intensify pain-linked sodium channel gating effects and persistent currents

In Special Collection:
Neuroscience Collection 2023 , Physiology of Pain Detection and Processing Collection 2023
Sophia Kriegeskorte, Raya Bott, Martin Hampl, Alon Korngreen, Ralf Hausmann, Angelika Lampert
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202213312.
https://doi.org/10.1085/jgp.202213312
Published: 02 August 2023
View article titled, Cold and warmth intensify pain-linked sodium channel gating effects and persistent currents
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Includes: Supplementary data
Journal Articles

Different species, different gap junctions?

Rafael Sanz-Gálvez, Arlette Kolta
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202313430.
https://doi.org/10.1085/jgp.202313430
Published: 01 August 2023
View article titled, Different species, different gap junctions?
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Journal Articles

Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse

Adrien Lesage, Maxime Lorenzini, Sophie Burel, Marine Sarlandie, Floriane Bibault, Cecilia Lindskog, Daniel Maloney, Jonathan R. Silva, R. Reid Townsend, Jeanne M. Nerbonne, Céline Marionneau
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202213293.
https://doi.org/10.1085/jgp.202213293
Published: 27 July 2023
View article titled, Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse
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Includes: Supplementary data
Journal Articles

Kv12-encoded K+ channels drive the day–night switch in the repetitive firing rates of SCN neurons

In Special Collection:
Neuroscience Collection 2023
Tracey O. Hermanstyne, Nien-Du Yang, Daniel Granados-Fuentes, Xiaofan Li, Rebecca L. Mellor, Timothy Jegla, Erik D. Herzog, Jeanne M. Nerbonne
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202213310.
https://doi.org/10.1085/jgp.202213310
Published: 26 July 2023
View article titled, Kv12-encoded K+ channels drive the day–night switch in the repetitive firing rates of SCN neurons
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Includes: Supplementary data
Journal Articles

D-type K+ current rules the function of electrically coupled neurons in a species-specific fashion

In Special Collection:
Neuroscience Collection 2023 , Physiology of Pain Detection and Processing Collection 2023
Antonella Dapino, Federico Davoine, Sebastian Curti
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202313353.
https://doi.org/10.1085/jgp.202313353
Published: 28 June 2023
View article titled, D-type K+ current rules the function of electrically coupled neurons in a species-specific fashion
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Includes: Supplementary data
Journal Articles

Patch-clamp technique to study mitochondrial membrane biophysics

In Special Collection:
Physiology of Pain Detection and Processing Collection 2023
Anshu Kumari, Dung M. Nguyen, Vivek Garg
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (8): e202313347.
https://doi.org/10.1085/jgp.202313347
Published: 22 June 2023
View article titled, Patch-clamp technique to study mitochondrial membrane biophysics
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Journal Articles

Binding motif for RIC-3 chaperon protein in serotonin type 3A receptors

Hoa Quynh Do, Michaela Jansen
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (6): e202213305.
https://doi.org/10.1085/jgp.202213305
Published: 07 April 2023
View article titled, Binding motif for RIC-3 chaperon protein in serotonin type 3A receptors
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Includes: Supplementary data
Journal Articles

Blue flash sheds light on the roles of individual phosphoserines in CFTR channel activation

László Csanády
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (6): e202313336.
https://doi.org/10.1085/jgp.202313336
Published: 05 April 2023
View article titled, Blue flash sheds light on the roles of individual phosphoserines in CFTR channel activation
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Journal Articles

Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors

Paweorn Angsutararux, Amal K. Dutta, Martina Marras, Carlota Abella, Rebecca L. Mellor, Jingyi Shi, Jeanne M. Nerbonne, Jonathan R. Silva
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (5): e202213300.
https://doi.org/10.1085/jgp.202213300
Published: 21 March 2023
View article titled, Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors
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Includes: Supplementary data
Journal Articles

Real-time observation of functional specialization among phosphorylation sites in CFTR

In Special Collection:
Molecular Insights into Membrane Protein Function
Daniel T. Infield, Miranda E. Schene, Frederico S. Fazan, Grace D. Galles, Jason D. Galpin, Christopher A. Ahern
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (4): e202213216.
https://doi.org/10.1085/jgp.202213216
Published: 25 January 2023
View article titled, Real-time observation of functional specialization among phosphorylation sites in CFTR
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Includes: Supplementary data
Journal Articles

Charge-voltage curves of Shaker potassium channel are not hysteretic at steady state

In Special Collection:
Biophysics 2024
John Cowgill, Baron Chanda
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (3): e202112883.
https://doi.org/10.1085/jgp.202112883
Published: 24 January 2023
View article titled, Charge-voltage curves of Shaker potassium channel are not hysteretic at steady state
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Journal Articles

Acid-sensing ion channel 1a activates IKCa/SKCa channels and contributes to endothelium-dependent dilation

Selina M. Garcia, Jay S. Naik, Thomas C. Resta, Nikki L. Jernigan
Journal: Journal of General Physiology
J Gen Physiol (2022) 155 (2): e202213173.
https://doi.org/10.1085/jgp.202213173
Published: 09 December 2022
View article titled, Acid-sensing ion channel 1a activates IKCa/SKCa channels and contributes to endothelium-dependent dilation
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Journal Articles

Reconstituting depolarization-induced calcium release

Ben Short
Journal: Journal of General Physiology
J Gen Physiol (2022) 154 (12): e202213287.
https://doi.org/10.1085/jgp.202213287
Published: 04 November 2022
View article titled, Reconstituting depolarization-induced calcium release
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