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Jonathan R. Silva
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Journal Articles

Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse

Adrien Lesage, Maxime Lorenzini, Sophie Burel, Marine Sarlandie, Floriane Bibault, Cecilia Lindskog, Daniel Maloney, Jonathan R. Silva, R. Reid Townsend, Jeanne M. Nerbonne, Céline Marionneau
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202213293.
https://doi.org/10.1085/jgp.202213293
Published: 27 July 2023
View article titled, Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse
Open the PDF for Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse in another window
Includes: Supplementary data
Journal Articles

Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors

Paweorn Angsutararux, Amal K. Dutta, Martina Marras, Carlota Abella, Rebecca L. Mellor, Jingyi Shi, Jeanne M. Nerbonne, Jonathan R. Silva
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (5): e202213300.
https://doi.org/10.1085/jgp.202213300
Published: 21 March 2023
View article titled, Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors
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Includes: Supplementary data
Journal Articles

Conformations of voltage-sensing domain III differentially define NaV channel closed- and open-state inactivation

Paweorn Angsutararux, Po Wei Kang, Wandi Zhu, Jonathan R. Silva
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (9): e202112891.
https://doi.org/10.1085/jgp.202112891
Published: 04 August 2021
View article titled, Conformations of voltage-sensing domain III differentially define NaV channel closed- and open-state inactivation
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Journal Articles

Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation sites

In Special Collection:
Cardiac Physiology 2021
Maxime Lorenzini, Sophie Burel, Adrien Lesage, Emily Wagner, Camille Charrière, Pierre-Marie Chevillard, Bérangère Evrard, Dan Maloney, Kiersten M. Ruff, Rohit V. Pappu, Stefan Wagner, Jeanne M. Nerbonne, Jonathan R. Silva, R. Reid Townsend, Lars S. Maier, Céline Marionneau
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (2): e202012646.
https://doi.org/10.1085/jgp.202012646
Published: 07 January 2021
View article titled, Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation sites
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Includes: Supplementary data
Journal Articles

Mechanisms of noncovalent β subunit regulation of NaV channel gating

In Special Collection:
Cardiovascular Physiology 2018
Wandi Zhu, Taylor L. Voelker, Zoltan Varga, Angela R. Schubert, Jeanne M. Nerbonne, Jonathan R. Silva
Journal: Journal of General Physiology
J Gen Physiol (2017) 149 (8): 813–831.
https://doi.org/10.1085/jgp.201711802
Published: 18 July 2017
View article titled, Mechanisms of noncovalent β subunit regulation of NaV channel gating
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Includes: Supplementary data
Journal Articles

Regulation of Na+ channel inactivation by the DIII and DIV voltage-sensing domains

In Special Collection:
Cardiovascular Physiology 2018
Eric J. Hsu, Wandi Zhu, Angela R. Schubert, Taylor Voelker, Zoltan Varga, Jonathan R. Silva
Journal: Journal of General Physiology
J Gen Physiol (2017) 149 (3): 389–403.
https://doi.org/10.1085/jgp.201611678
Published: 23 February 2017
View article titled, Regulation of Na+ channel inactivation by the DIII and DIV voltage-sensing domains
Open the PDF for Regulation of Na+ channel inactivation by the DIII and DIV voltage-sensing domains in another window
Includes: Supplementary data
Journal Articles

Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels II: A periodic paralysis mutation in NaV1.4 (L689I)

Jonathan R. Silva, Steve A.N. Goldstein
Journal: Journal of General Physiology
J Gen Physiol (2013) 141 (3): 323–334.
https://doi.org/10.1085/jgp.201210910
Published: 11 February 2013
View article titled, Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels II: A periodic paralysis mutation in NaV1.4 (L689I)
Open the PDF for Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels II: A periodic paralysis mutation in NaV1.4 (L689I) in another window
Journal Articles

Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels I: Wild-type skeletal muscle NaV1.4

Jonathan R. Silva, Steve A.N. Goldstein
Journal: Journal of General Physiology
J Gen Physiol (2013) 141 (3): 309–321.
https://doi.org/10.1085/jgp.201210909
Published: 11 February 2013
View article titled, Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels I: Wild-type skeletal muscle NaV1.4
Open the PDF for Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels I: Wild-type skeletal muscle NaV1.4 in another window
Includes: Supplementary data
Journal Articles

Multi-scale electrophysiology modeling: from atom to organ

Jonathan R. Silva, Yoram Rudy
Journal: Journal of General Physiology
Series: Perspectives on: Molecular dynamics and computational methods
J Gen Physiol (2010) 135 (6): 575–581.
https://doi.org/10.1085/jgp.200910358
Published: 31 May 2010
View article titled, Multi-scale electrophysiology modeling: from atom to organ
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