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Xiaoxia Li
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Journal Articles

Act1 drives chemoresistance via regulation of antioxidant RNA metabolism and redox homeostasis

In Special Collection:
Mechanisms and Models of Cancer 2024 , Tumor Metabolism 2025 , 2024: The Year in Experimental Medicine
Lingzi Hong, Tomasz Herjan, Xing Chen, Leah L. Zagore, Katarzyna Bulek, Han Wang, Chi-Fu Jeffrey Yang, Donny D. Licatalosi, Xiaoxia Li, Xiao Li
Journal: Journal of Experimental Medicine
J Exp Med (2024) 221 (7): e20231442.
https://doi.org/10.1084/jem.20231442
Published: 11 June 2024
View article titled, Act1 drives chemoresistance via regulation of antioxidant RNA metabolism and redox homeostasis
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Includes: Supplementary data
Journal Articles

IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast-mediated immune exclusion

In Special Collection:
JEM Cancer Immunotherapy 2022 , JEM Mucosal Immunology 2022 , Mechanisms and Models of Cancer 2022 Update
Xing Chen, Junjie Zhao, Tomasz Herjan, Lingzi Hong, Yun Liao, Caini Liu, Kommireddy Vasu, Han Wang, Austin Thompson, Paul L. Fox, Brian R. Gastman, Xiao Li, Xiaoxia Li
Journal: Journal of Experimental Medicine
J Exp Med (2022) 219 (6): e20210693.
https://doi.org/10.1084/jem.20210693
Published: 07 April 2022
View article titled, IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast-mediated immune exclusion
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Includes: Supplementary data
Journal Articles

Inflammasome-independent functions of AIM2

Junjie Zhao, William Miller-Little, Xiaoxia Li
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (5): e20210273.
https://doi.org/10.1084/jem.20210273
Published: 09 April 2021
View article titled, Inflammasome-independent functions of AIM2
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Journal Articles

The role of interleukin-17 in tumor development and progression

In Special Collection:
JEM 2020 Update on Cancer Immunology and Immunotherapy
Junjie Zhao, Xing Chen, Tomasz Herjan, Xiaoxia Li
Journal: Journal of Experimental Medicine
Series: Cytokines Focus
J Exp Med (2019) 217 (1): e20190297.
https://doi.org/10.1084/jem.20190297
Published: 14 November 2019
View article titled, The role of interleukin-17 in tumor development and progression
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Journal Articles

IL-17R–EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells

In Special Collection:
Cytokines 2019 , A Collection for the 59th Midwinter Conference of Immunologists at Asilomar
Xing Chen, Gang Cai, Caini Liu, Junjie Zhao, Chunfang Gu, Ling Wu, Thomas A. Hamilton, Cun-jin Zhang, Jennifer Ko, Liang Zhu, Jun Qin, Allison Vidimos, Shlomo Koyfman, Brian R. Gastman, Kim B. Jensen, Xiaoxia Li
Journal: Journal of Experimental Medicine
J Exp Med (2018) 216 (1): 195–214.
https://doi.org/10.1084/jem.20171849
Published: 21 December 2018
View article titled, IL-17R–EGFR axis links wound healing to tumorigenesis in Lrig1<sup>+</sup> stem cells
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Includes: Supplementary data
Journal Articles

LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection

Weiwei Liu, Xia’nan Liu, Yu Li, Junjie Zhao, Zhenshan Liu, Zhuqin Hu, Ying Wang, Yufeng Yao, Aaron W. Miller, Bing Su, Mark R. Cookson, Xiaoxia Li, Zizhen Kang
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (10): 3051–3066.
https://doi.org/10.1084/jem.20170014
Published: 18 August 2017
View article titled, LRRK2 promotes the activation of NLRC4 inflammasome during <em>Salmonella</em> Typhimurium infection
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Includes: Supplementary data
Journal Articles

A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4–ERK5 axis

Ling Wu, Xing Chen, Junjie Zhao, Bradley Martin, Jarod A. Zepp, Jennifer S. Ko, Chunfang Gu, Gang Cai, Wenjun Ouyang, Ganes Sen, George R. Stark, Bing Su, Charlotte M. Vines, Cathy Tournier, Thomas A. Hamilton, Allison Vidimos, Brian Gastman, Caini Liu, Xiaoxia Li
Journal: Journal of Experimental Medicine
J Exp Med (2015) 212 (10): 1571–1587.
https://doi.org/10.1084/jem.20150204
Published: 07 September 2015
View article titled, A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4–ERK5 axis
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Includes: Supplementary data
Journal Articles

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases

Minjia Yu, Hao Zhou, Junjie Zhao, Nengming Xiao, Sanjoy Roychowdhury, David Schmitt, Bingqing Hu, Richard M. Ransohoff, Clifford V. Harding, Amy G. Hise, Stanley L. Hazen, Anthony L. DeFranco, Paul L. Fox, Richard E. Morton, Paul E. Dicorleto, Maria Febbraio, Laura E. Nagy, Jonathan D. Smith, Jian-an Wang, Xiaoxia Li
Journal: Journal of Experimental Medicine
J Exp Med (2014) 211 (5): 1003.
https://doi.org/10.1084/jem.2013131404222014c
Published: 05 May 2014
View article titled, MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases
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Journal Articles

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases

Minjia Yu, Hao Zhou, Junjie Zhao, Nengming Xiao, Sanjoy Roychowdhury, David Schmitt, Bingqing Hu, Richard M. Ransohoff, Clifford V. Harding, Amy G. Hise, Stanley L. Hazen, Anthony L. DeFranco, Paul L. Fox, Richard E. Morton, Paul E. Dicorleto, Maria Febbraio, Laura E. Nagy, Jonathan D. Smith, Jian-an Wang, Xiaoxia Li
Journal: Journal of Experimental Medicine
J Exp Med (2014) 211 (5): 887–907.
https://doi.org/10.1084/jem.20131314
Published: 21 April 2014
View article titled, MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases
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Journal Articles

Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling

Shu Zhu, Wen Pan, Peiqing Shi, Hanchao Gao, Fang Zhao, Xinyang Song, Yan Liu, Lihua Zhao, Xiaoxia Li, Yufang Shi, Youcun Qian
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (12): 2647–2662.
https://doi.org/10.1084/jem.20100703
Published: 15 November 2010
View article titled, Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling
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Includes: Supplementary data
Journal Articles

Selective predisposition to bacterial infections in IRAK-4–deficient children: IRAK-4–dependent TLRs are otherwise redundant in protective immunity

Cheng-Lung Ku, Horst von Bernuth, Capucine Picard, Shen-Ying Zhang, Huey-Hsuan Chang, Kun Yang, Maya Chrabieh, Andrew C. Issekutz, Coleen K. Cunningham, John Gallin, Steven M. Holland, Chaim Roifman, Stephan Ehl, Joanne Smart, Mimi Tang, Franck J. Barrat, Ofer Levy, Douglas McDonald, Noorbibi K. Day-Good, Richard Miller, Hidetoshi Takada, Toshiro Hara, Sami Al-Hajjar, Abdulaziz Al-Ghonaium, David Speert, Damien Sanlaville, Xiaoxia Li, Frédéric Geissmann, Eric Vivier, László Maródi, Ben-Zion Garty, Helen Chapel, Carlos Rodriguez-Gallego, Xavier Bossuyt, Laurent Abel, Anne Puel, Jean-Laurent Casanova
Journal: Journal of Experimental Medicine
J Exp Med (2007) 204 (10): 2407–2422.
https://doi.org/10.1084/jem.20070628
Published: 24 September 2007
View article titled, Selective predisposition to bacterial infections in IRAK-4–deficient children: IRAK-4–dependent TLRs are otherwise redundant in protective immunity
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Includes: Supplementary data
Journal Articles

A critical role for IRAK4 kinase activity in Toll-like receptor–mediated innate immunity

Tae Whan Kim, Kirk Staschke, Katarzyna Bulek, Jianhong Yao, Kristi Peters, Keun-Hee Oh, Yvonne Vandenburg, Hui Xiao, Wen Qian, Tom Hamilton, Booki Min, Ganes Sen, Raymond Gilmour, Xiaoxia Li
Journal: Journal of Experimental Medicine
J Exp Med (2007) 204 (5): 1025–1036.
https://doi.org/10.1084/jem.20061825
Published: 30 April 2007
View article titled, A critical role for IRAK4 kinase activity in Toll-like receptor–mediated innate immunity
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