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A partial human LCK defect causes a T cell immunodeficiency with intestinal inflammation

In Special Collection:

Thymus, T Cell Development, and Inborn Errors , Immunology Update Winter 2024

J Exp Med (2023) 221 (1): e20230927.

https://doi.org/10.1084/jem.20230927

Published: 14 November 2023

View article titled, A partial human LCK defect causes a T cell immunodeficiency with intestinal inflammation

Includes: Supplementary data

Journal Articles

Goldilocks and the three TILs

Hannah Dada, Michael L. Dustin

J Exp Med (2022) 219 (2): e20212269.

https://doi.org/10.1084/jem.20212269

Published: 12 January 2022

View article titled, Goldilocks and the three TILs

Journal Articles

PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

Bernd H. Zinselmeyer, Sara Heydari, Catarina Sacristán, Debasis Nayak, Michael Cammer, Jasmin Herz, Xiaoxiao Cheng, Simon J. Davis, Michael L. Dustin, Dorian B. McGavern

J Exp Med (2013) 210 (4): 757–774.

https://doi.org/10.1084/jem.20121416

Published: 25 March 2013

View article titled, PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

Includes: Supplementary data

Journal Articles

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3⁺ T reg cells

J Exp Med (2012) 209 (10): 1723–1742.

https://doi.org/10.1084/jem.20120914

Published: 10 September 2012

View article titled, Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3<sup>+</sup> T reg cells

Includes: Supplementary data

Journal Articles

Self-reactive human CD4 T cell clones form unusual immunological synapses

David A. Schubert, Susana Gordo, Joseph J. Sabatino, Jr., Santosh Vardhana, Etienne Gagnon, Dhruv K. Sethi, Nilufer P. Seth, Kaushik Choudhuri, Helena Reijonen, Gerald T. Nepom, Brian D. Evavold, Michael L. Dustin, Kai W. Wucherpfennig

J Exp Med (2012) 209 (2): 335–352.

https://doi.org/10.1084/jem.20111485

Published: 06 February 2012

View article titled, Self-reactive human CD4 T cell clones form unusual immunological synapses

Includes: Supplementary data

Journal Articles

Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain

Niroshana Anandasabapathy, Gabriel D. Victora, Matthew Meredith, Rachel Feder, Baojun Dong, Courtney Kluger, Kaihui Yao, Michael L. Dustin, Michel C. Nussenzweig, Ralph M. Steinman, Kang Liu

J Exp Med (2011) 208 (8): 1695–1705.

https://doi.org/10.1084/jem.20102657

Published: 25 July 2011

View article titled, Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain

Includes: Supplementary data

Journal Articles

A dynamic T cell–limited checkpoint regulates affinity-dependent B cell entry into the germinal center

Tanja A. Schwickert, Gabriel D. Victora, David R. Fooksman, Alice O. Kamphorst, Monica R. Mugnier, Alexander D. Gitlin, Michael L. Dustin, Michel C. Nussenzweig

J Exp Med (2011) 208 (6): 1243–1252.

https://doi.org/10.1084/jem.20102477

Published: 16 May 2011

View article titled, A dynamic T cell–limited checkpoint regulates affinity-dependent B cell entry into the germinal center

Includes: Supplementary data

Journal Articles

Migration of cytotoxic lymphocytes in cell cycle permits local MHC I–dependent control of division at sites of viral infection

Silvia S. Kang, Jasmin Herz, Jiyun V. Kim, Debasis Nayak, Phillip Stewart-Hutchinson, Michael L. Dustin, Dorian B. McGavern

J Exp Med (2011) 208 (4): 747–759.

https://doi.org/10.1084/jem.20101295

Published: 04 April 2011

View article titled, Migration of cytotoxic lymphocytes in cell cycle permits local MHC I–dependent control of division at sites of viral infection

Includes: Supplementary data

Journal Articles

Affinity measured by microcluster

David R. Fooksman, Michael L. Dustin

J Exp Med (2010) 207 (5): 907–909.

https://doi.org/10.1084/jem.20100780

Published: 03 May 2010

View article titled, Affinity measured by microcluster

Journal Articles

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

Guillaume Darrasse-Jèze, Stephanie Deroubaix, Hugo Mouquet, Gabriel D. Victora, Thomas Eisenreich, Kai-hui Yao, Revati F. Masilamani, Michael L. Dustin, Alexander Rudensky, Kang Liu, Michel C. Nussenzweig

J Exp Med (2009) 206 (9): 1853–1862.

https://doi.org/10.1084/jem.20090746

Published: 10 August 2009

View article titled, Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

Includes: Supplementary data

Journal Articles

Regulatory T cells inhibit stable contacts between CD4⁺ T cells and dendritic cells in vivo

Carlos E. Tadokoro, Guy Shakhar, Shiqian Shen, Yi Ding, Andreia C. Lino, Antonio Maraver, Juan J. Lafaille, Michael L. Dustin

J Exp Med (2006) 203 (3): 505–511.

https://doi.org/10.1084/jem.20050783

Published: 13 March 2006

View article titled, Regulatory T cells inhibit stable contacts between CD4<sup>+</sup> T cells and dendritic cells in vivo

Includes: Supplementary data

Journal Articles

Actin and agonist MHC–peptide complex–dependent T cell receptor microclusters as scaffolds for signaling

Gabriele Campi, Rajat Varma, Michael L. Dustin

J Exp Med (2005) 202 (8): 1031–1036.

https://doi.org/10.1084/jem.20051182

Published: 10 October 2005

View article titled, Actin and agonist MHC–peptide complex–dependent T cell receptor microclusters as scaffolds for signaling

Journal Articles

The Lymphocyte Function–associated Antigen 1 I Domain Is a Transient Binding Module for Intercellular Adhesion Molecule (ICAM)-1 and ICAM-3 in Hydrodynamic Flow

Ruth Knorr, Michael L. Dustin

J Exp Med (1997) 186 (5): 719–730.

https://doi.org/10.1084/jem.186.5.719

Published: 29 August 1997

View article titled, The Lymphocyte Function–associated Antigen 1 I Domain Is a Transient Binding Module for Intercellular Adhesion Molecule (ICAM)-1 and ICAM-3 in Hydrodynamic Flow

NARROW

A partial human LCK defect causes a T cell immunodeficiency with intestinal inflammation

Goldilocks and the three TILs

PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3⁺ T reg cells

Self-reactive human CD4 T cell clones form unusual immunological synapses

Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain

A dynamic T cell–limited checkpoint regulates affinity-dependent B cell entry into the germinal center

Migration of cytotoxic lymphocytes in cell cycle permits local MHC I–dependent control of division at sites of viral infection

Affinity measured by microcluster

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

Regulatory T cells inhibit stable contacts between CD4⁺ T cells and dendritic cells in vivo

Actin and agonist MHC–peptide complex–dependent T cell receptor microclusters as scaffolds for signaling

The Lymphocyte Function–associated Antigen 1 I Domain Is a Transient Binding Module for Intercellular Adhesion Molecule (ICAM)-1 and ICAM-3 in Hydrodynamic Flow

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