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Kai W. Wucherpfennig
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Journal Articles

Correction: Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells

Rong En Tay, Olamide Olawoyin, Paloma Cejas, Yingtian Xie, Clifford A. Meyer, Yoshinaga Ito, Qing Yu Weng, David E. Fisher, Henry W. Long, Myles Brown, Hye-Jung Kim, Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (7): e2019145305152020c.
https://doi.org/10.1084/jem.2019145305152020c
Published: 22 May 2020
View article titled, Correction: Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells
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Journal Articles

Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells

Rong En Tay, Olamide Olawoyin, Paloma Cejas, Yingtian Xie, Clifford A. Meyer, Yoshinaga Ito, Qing Yu Weng, David E. Fisher, Henry W. Long, Myles Brown, Hye-Jung Kim, Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (7): e20191453.
https://doi.org/10.1084/jem.20191453
Published: 06 May 2020
View article titled, Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells
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Includes: Supplementary data
Journal Articles

Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity

In Special Collection:
Autoimmunity: Mechanisms and Novel Treatments , Cancer and Autoimmunity
Yoshinaga Ito, Orr Ashenberg, Jason Pyrdol, Adrienne M. Luoma, Orit Rozenblatt-Rosen, Matan Hofree, Elena Christian, Lucas Ferrari de Andrade, Rong En Tay, Luc Teyton, Aviv Regev, Stephanie K. Dougan, Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (10): 2617–2635.
https://doi.org/10.1084/jem.20180300
Published: 05 September 2018
View article titled, Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity
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Includes: Supplementary data
Journal Articles

Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain

Etienne Gagnon, David A. Schubert, Susana Gordo, H. Hamlet Chu, Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (2012) 209 (13): 2423–2439.
https://doi.org/10.1084/jem.20120790
Published: 19 November 2012
View article titled, Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain
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Includes: Supplementary data
Journal Articles

Self-reactive human CD4 T cell clones form unusual immunological synapses

David A. Schubert, Susana Gordo, Joseph J. Sabatino, Jr., Santosh Vardhana, Etienne Gagnon, Dhruv K. Sethi, Nilufer P. Seth, Kaushik Choudhuri, Helena Reijonen, Gerald T. Nepom, Brian D. Evavold, Michael L. Dustin, Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (2012) 209 (2): 335–352.
https://doi.org/10.1084/jem.20111485
Published: 06 February 2012
View article titled, Self-reactive human CD4 T cell clones form unusual immunological synapses
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Includes: Supplementary data
Journal Articles

A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC

Dhruv K. Sethi, David A. Schubert, Anne-Kathrin Anders, Annie Heroux, Daniel A. Bonsor, Chantz P. Thomas, Eric J. Sundberg, Jason Pyrdol, Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (2011) 208 (1): 91–102.
https://doi.org/10.1084/jem.20100725
Published: 03 January 2011
View article titled, A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC
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Includes: Supplementary data
Journal Articles

Presentation of a Self-peptide in Two Distinct Conformations by a Disease-associated HLA-B27 Subtype

Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (2004) 199 (2): 151–154.
https://doi.org/10.1084/jem.20032050
Published: 20 January 2004
View article titled, Presentation of a Self-peptide in Two Distinct Conformations by a Disease-associated HLA-B27 Subtype
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Journal Articles

Visualization of Myelin Basic Protein (Mbp) T Cell Epitopes in Multiple Sclerosis Lesions Using a Monoclonal Antibody Specific for the Human Histocompatibility Leukocyte Antigen (Hla)-Dr2–Mbp 85–99 Complex

Michelle Krogsgaard, Kai W. Wucherpfennig, Barbara Canella, Bjarke E. Hansen, Arne Svejgaard, Jason Pyrdol, Henrik Ditzel, Cedric Raine, Jan Engberg, Lars Fugger
Journal: Journal of Experimental Medicine
J Exp Med (2000) 191 (8): 1395–1412.
https://doi.org/10.1084/jem.191.8.1395
Published: 18 April 2000
View article titled, Visualization of Myelin Basic Protein (Mbp) T Cell Epitopes in Multiple Sclerosis Lesions Using a Monoclonal Antibody Specific for the Human Histocompatibility Leukocyte Antigen (Hla)-Dr2–Mbp 85–99 Complex
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Journal Articles

pH-dependent Peptide Binding Properties of the Type I Diabetes–associated I-Ag7 Molecule: Rapid Release of CLIP at an Endosomal pH

Dorothee H.F. Hausmann, Bei Yu, Stefan Hausmann, Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (1999) 189 (11): 1723–1734.
https://doi.org/10.1084/jem.189.11.1723
Published: 07 June 1999
View article titled, pH-dependent Peptide Binding Properties of the Type I Diabetes–associated I-A<sup>g7</sup> Molecule: Rapid Release of CLIP at an Endosomal pH
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Journal Articles

In Vivo Survival of  Viral Antigen–specific T Cells that Induce Experimental Autoimmune Encephalomyelitis

Rafael L. Ufret-Vincenty, Laura Quigley, Nancy Tresser, Seong Hee Pak, Ameer Gado, Stefan Hausmann, Kai W. Wucherpfennig, Stefan Brocke
Journal: Journal of Experimental Medicine
J Exp Med (1998) 188 (9): 1725–1738.
https://doi.org/10.1084/jem.188.9.1725
Published: 02 November 1998
View article titled, In Vivo Survival of  Viral Antigen–specific T Cells that Induce Experimental Autoimmune Encephalomyelitis
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Journal Articles

Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein

Kathrine J. Smith, Jason Pyrdol, Laurent Gauthier, Don C. Wiley, Kai W. Wucherpfennig
Journal: Journal of Experimental Medicine
J Exp Med (1998) 188 (8): 1511–1520.
https://doi.org/10.1084/jem.188.8.1511
Published: 19 October 1998
View article titled, Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein
Open the PDF for Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein in another window