Issues

Editorial

Developments at The JEM

Jennifer Bell
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Article

The Adaptor Protein AP-3 Is Required for CD1d-Mediated Antigen Presentation of Glycosphingolipids and Development of Vα14i NKT Cells

Dirk Elewaut,Anna P. Lawton,Niranjana A. Nagarajan,Emanual Maverakis,Archana Khurana,Stefan Höning,Chris A. Benedict,Eli Sercarz,Oddmund Bakke,Mitchell Kronenberg,Theodore I. Prigozy
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Molecular Mimicry between Helicobacter pylori Antigens and H+,K+–Adenosine Triphosphatase in Human Gastric Autoimmunity

Amedeo Amedei,Mathijs P. Bergman,Ben J. Appelmelk,Annalisa Azzurri,Marisa Benagiano,Carlo Tamburini,Ruurd van der Zee,John L. Telford,Christina M.J.E. Vandenbroucke-Grauls,Mario M. D'Elios,Gianfranco Del Prete
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Normal Induction but Attenuated Progression of Germinal Center Responses in BAFF and BAFF-R Signaling–Deficient Mice

Ziaur SM. Rahman,Sambasiva P. Rao,Susan L. Kalled,Tim Manser
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Msh2 ATPase Activity Is Essential for Somatic Hypermutation at A-T Basepairs and for Efficient Class Switch Recombination

Alberto Martin,Ziqiang Li,Diana P. Lin,Philip D. Bardwell,Maria D. Iglesias-Ussel,Winfried Edelmann,Matthew D. Scharff
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Transforming Growth Factor (TGF)-β1–producing Regulatory T Cells Induce Smad-mediated Interleukin 10 Secretion That Facilitates Coordinated Immunoregulatory Activity and Amelioration of TGF-β1–mediated Fibrosis

Atsushi Kitani,Ivan Fuss,Kazuhiko Nakamura,Fumiyuki Kumaki,Takashi Usui,Warren Strober
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Targeted Inactivation of the IL-4 Receptor α Chain I4R Motif Promotes Allergic Airway Inflammation

Frank Blaeser,Paul J. Bryce,Nga Ho,Vidya Raman,Fatma Dedeoglu,Debra D. Donaldson,Raif S. Geha,Hans C. Oettgen,Talal A. Chatila
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Human Decidual Natural Killer Cells Are a Unique NK Cell Subset with Immunomodulatory Potential

Louise A. Koopman,Hernan D. Kopcow,Basya Rybalov,Jonathan E. Boyson,Jordan S. Orange,Frederick Schatz,Rachel Masch,Charles J. Lockwood,Asher D. Schachter,Peter J. Park,Jack L. Strominger
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Elimination In Vivo of Developing T Cells by Natural Killer Cells

Eckart Schott,Roberto Bonasio,Hidde L. Ploegh
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Intracellular Recognition of Lipopolysaccharide by Toll-like Receptor 4 in Intestinal Epithelial Cells

Mathias W. Hornef,Birgitta Henriques Normark,Alain Vandewalle,Staffan Normark
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A Critical Role for OX40 in T Cell–mediated Immunopathology during Lung Viral Infection

Ian R. Humphreys,Gerhard Walzl,Lorna Edwards,Aaron Rae,Sue Hill,Tracy Hussell
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Prevention of Lipopolysaccharide-induced Microangiopathy by gp49B1 : Evidence for an Important Role for gp49B1 Expression on Neutrophils

Joseph S. Zhou,Daniel S. Friend,Anna M. Feldweg,Massoud Daheshia,Lin Li,K. Frank Austen,Howard R. Katz
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Lipopolysaccharide or Whole Bacteria Block the Conversion of Inflammatory Monocytes into Dendritic Cells In Vivo

Gianluca Rotta,Emmerson W. Edwards,Sabina Sangaletti,Clare Bennett,Simona Ronzoni,Mario P. Colombo,Ralph M. Steinman,Gwendalyn J. Randolph,Maria Rescigno
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Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

Jianguo Liu,Shanjin Cao,Lisa M. Herman,Xiaojing Ma
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Brief Definitive Report

Thrombospondin 1 Is an Autocrine Negative Regulator of Human Dendritic Cell Activation

Virginie Doyen,Manuel Rubio,Deborah Braun,Toshiaru Nakajima,Jun Abe,Hirohisa Saito,Guy Delespesse,Marika Sarfati
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