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Journal Articles

Lineage-specific regulation of inducible and constitutive mast cells in allergic airway inflammation

Tahereh Derakhshan, Sachin K. Samuchiwal, Nils Hallen, Lora G. Bankova, Joshua A. Boyce, Nora A. Barrett, K. Frank Austen, Daniel F. Dwyer

J Exp Med (2020) 218 (1): e20200321.

https://doi.org/10.1084/jem.20200321

Published: 18 September 2020

View article titled, Lineage-specific regulation of inducible and constitutive mast cells in allergic airway inflammation

Includes: Supplementary data

Journal Articles

Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s

Jakob von Moltke, Claire E. O’Leary, Nora A. Barrett, Yoshihide Kanaoka, K. Frank Austen, Richard M. Locksley

J Exp Med (2016) 214 (1): 27–37.

https://doi.org/10.1084/jem.20161274

Published: 23 December 2016

View article titled, Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s

Includes: Supplementary data

Journal Articles

Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes

Nora A. Barrett, Opu M. Rahman, James M. Fernandez, Matthew W. Parsons, Wei Xing, K. Frank Austen, Yoshihide Kanaoka

J Exp Med (2011) 208 (3): 593–604.

https://doi.org/10.1084/jem.20100793

Published: 28 February 2011

View article titled, Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes

Includes: Supplementary data

Journal Articles

Mast cell deficiency in Kit^W-sh mice does not impair antibody-mediated arthritis

Joseph S. Zhou, Wei Xing, Daniel S. Friend, K. Frank Austen, Howard R. Katz

J Exp Med (2007) 204 (12): 2797–2802.

https://doi.org/10.1084/jem.20071391

Published: 12 November 2007

View article titled, Mast cell deficiency in KitW-sh mice does not impair antibody-mediated arthritis

Journal Articles

Neutrophil-derived leukotriene B₄ is required for inflammatory arthritis

Mei Chen, Bing K. Lam, Yoshihide Kanaoka, Peter A. Nigrovic, Laurent P. Audoly, K. Frank Austen, David M. Lee

J Exp Med (2006) 203 (4): 837–842.

https://doi.org/10.1084/jem.20052371

Published: 27 March 2006

View article titled, Neutrophil-derived leukotriene B4 is required for inflammatory arthritis

Includes: Supplementary data

Journal Articles

No audible wheezing : nuggets and conundrums from mouse asthma models

Joshua A. Boyce, K. Frank Austen

J Exp Med (2005) 201 (12): 1869–1873.

https://doi.org/10.1084/jem.20050584

Published: 20 June 2005

View article titled, No audible wheezing : <subtitle>nuggets and conundrums from mouse asthma models </subtitle>

Journal Articles

Prevention of Lipopolysaccharide-induced Microangiopathy by gp49B1 : Evidence for an Important Role for gp49B1 Expression on Neutrophils

Joseph S. Zhou, Daniel S. Friend, Anna M. Feldweg, Massoud Daheshia, Lin Li, K. Frank Austen, Howard R. Katz

J Exp Med (2003) 198 (8): 1243–1251.

https://doi.org/10.1084/jem.20030906

Published: 13 October 2003

View article titled, Prevention of Lipopolysaccharide-induced Microangiopathy by gp49B1 : <subtitle>Evidence for an Important Role for gp49B1 Expression on Neutrophils </subtitle>

Journal Articles

Cysteinyl Leukotrienes and Uridine Diphosphate Induce Cytokine Generation by Human Mast Cells Through an Interleukin 4–regulated Pathway that Is Inhibited by Leukotriene Receptor Antagonists

Elizabeth A. Mellor, K. Frank Austen, Joshua A. Boyce

J Exp Med (2002) 195 (5): 583–592.

https://doi.org/10.1084/jem.20020044

Published: 04 March 2002

View article titled, Cysteinyl Leukotrienes and Uridine Diphosphate Induce Cytokine Generation by Human Mast Cells Through an Interleukin 4–regulated Pathway that Is Inhibited by Leukotriene Receptor Antagonists

Journal Articles

Intestinal Mast Cell Progenitors Require CD49dβ7 (α4β7 Integrin) for Tissue-specific Homing

Michael F. Gurish, Hong Tao, J. Pablo Abonia, Anu Arya, Daniel S. Friend, Christina M. Parker, K. Frank Austen

J Exp Med (2001) 194 (9): 1243–1252.

https://doi.org/10.1084/jem.194.9.1243

Published: 29 October 2001

View article titled, Intestinal Mast Cell Progenitors Require CD49dβ7 (α4β7 Integrin) for Tissue-specific Homing

Journal Articles

Increased Severity of Local and Systemic Anaphylactic Reactions in Gp49b1-Deficient Mice

Massoud Daheshia, Daniel S. Friend, Michael J. Grusby, K. Frank Austen, Howard R. Katz

J Exp Med (2001) 194 (2): 227–234.

https://doi.org/10.1084/jem.194.2.227

Published: 16 July 2001

View article titled, Increased Severity of Local and Systemic Anaphylactic Reactions in Gp49b1-Deficient Mice

Journal Articles

The Diverse Roles of Mast Cells

Michael F. Gurish, K. Frank Austen

J Exp Med (2001) 194 (1): F1–F6.

https://doi.org/10.1084/jem.194.1.F1

Published: 02 July 2001

View article titled, The Diverse Roles of Mast Cells

Journal Articles

T Helper Cell Type 2 Cytokines Coordinately Regulate Immunoglobulin E–Dependent Cysteinyl Leukotriene Production by Human Cord Blood–Derived Mast Cells: Profound Induction of Leukotriene C₄ Synthase Expression by Interleukin 4

Fred H. Hsieh, Bing K. Lam, John F. Penrose, K. Frank Austen, Joshua A. Boyce

J Exp Med (2001) 193 (1): 123–134.

https://doi.org/10.1084/jem.193.1.123

Published: 02 January 2001

View article titled, T Helper Cell Type 2 Cytokines Coordinately Regulate Immunoglobulin E–Dependent Cysteinyl Leukotriene Production by Human Cord Blood–Derived Mast Cells: <subtitle>Profound Induction of Leukotriene C4 Synthase Expression by Interleukin 4</subtitle>

Journal Articles

T Helper Cell Type 2 Cytokine–Mediated Comitogenic Responses and Ccr3 Expression during Differentiation of Human Mast Cells in Vitro

Hiroshi Ochi, W. Mona Hirani, Qian Yuan, Daniel S. Friend, K. Frank Austen, Joshua A. Boyce

J Exp Med (1999) 190 (2): 267–280.

https://doi.org/10.1084/jem.190.2.267

Published: 19 July 1999

View article titled, T Helper Cell Type 2 Cytokine–Mediated Comitogenic Responses and Ccr3 Expression during Differentiation of Human Mast Cells in Vitro

Journal Articles

Human Peripheral Blood Eosinophils Express a Functional c-kit Receptor for Stem Cell Factor that Stimulates Very Late Antigen 4 (VLA-4)–mediated Cell Adhesion to Fibronectin and Vascular Cell Adhesion Molecule 1 (VCAM-1)

Qian Yuan, K. Frank Austen, Daniel S. Friend, Matthew Heidtman, Joshua A. Boyce

J Exp Med (1997) 186 (2): 313–323.

https://doi.org/10.1084/jem.186.2.313

Published: 21 July 1997

View article titled, Human Peripheral Blood Eosinophils Express a Functional c-kit Receptor for Stem Cell Factor that Stimulates Very Late Antigen 4 (VLA-4)–mediated Cell Adhesion to Fibronectin and Vascular Cell Adhesion Molecule 1 (VCAM-1)

Journal Articles

FORMATION OF SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS IN HUMAN LUNG TISSUE AND CELLS BEFORE RELEASE

Robert A. Lewis, Stephen I. Wasserman, Edward J. Goetzl, K. Frank Austen

J Exp Med (1974) 140 (5): 1133–1146.

https://doi.org/10.1084/jem.140.5.1133

Published: 01 November 1974

View article titled, FORMATION OF SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS IN HUMAN LUNG TISSUE AND CELLS BEFORE RELEASE

Journal Articles

A NEUTROPHIL-DEPENDENT PATHWAY FOR THE GENERATION OF A NEUTRAL PEPTIDE MEDIATOR : PARTIAL CHARACTERIZATION OF COMPONENTS AND CONTROL BY α-1-ANTITRYPSIN

Bruce U. Wintroub, Edward J. Goetzl, K. Frank Austen

J Exp Med (1974) 140 (3): 812–824.

https://doi.org/10.1084/jem.140.3.812

Published: 01 September 1974

View article titled, A NEUTROPHIL-DEPENDENT PATHWAY FOR THE GENERATION OF A NEUTRAL PEPTIDE MEDIATOR : <subtitle>P<sc>ARTIAL</sc> C<sc>HARACTERIZATION OF</sc> C<sc>OMPONENTS AND</sc> C<sc>ONTROL</sc> B<sc>Y</sc> α-1-A<sc>NTITRYPSIN </sc></subtitle>

Journal Articles

PROPERDIN FACTOR D : II. ACTIVATION TO D BY PROPERDIN

Douglas T. Fearon, K. Frank Austen, Shaun Ruddy

J Exp Med (1974) 140 (2): 426–436.

https://doi.org/10.1084/jem.140.2.426

Published: 01 August 1974

View article titled, PROPERDIN FACTOR D : <subtitle>II. A<sc>CTIVATION TO D BY</sc> P<sc>ROPERDIN </sc></subtitle>

Journal Articles

PROPERDIN FACTOR D: CHARACTERIZATION OF ITS ACTIVE SITE AND ISOLATION OF THE PRECURSOR FORM

Douglas T. Fearon, K. Frank Austen, Shaun Ruddy

J Exp Med (1974) 139 (2): 355–366.

https://doi.org/10.1084/jem.139.2.355

Published: 01 February 1974

View article titled, PROPERDIN FACTOR D: CHARACTERIZATION OF ITS ACTIVE SITE AND ISOLATION OF THE PRECURSOR FORM

Journal Articles

FORMATION OF A HEMOLYTICALLY ACTIVE CELLULAR INTERMEDIATE BY THE INTERACTION BETWEEN PROPERDIN FACTORS B AND D AND THE ACTIVATED THIRD COMPONENT OF COMPLEMENT

Douglas T. Fearon, K. Frank Austen, Shaun Ruddy

J Exp Med (1973) 138 (6): 1305–1313.

https://doi.org/10.1084/jem.138.6.1305

Published: 01 December 1973

View article titled, FORMATION OF A HEMOLYTICALLY ACTIVE CELLULAR INTERMEDIATE BY THE INTERACTION BETWEEN PROPERDIN FACTORS B AND D AND THE ACTIVATED THIRD COMPONENT OF COMPLEMENT

Journal Articles

A SEQUENCE OF BIOCHEMICAL EVENTS IN THE ANTIGEN-INDUCED RELEASE OF CHEMICAL MEDIATORS FROM SENSITIZED HUMAN LUNG TISSUE

Michael Kaliner, K. Frank Austen

J Exp Med (1973) 138 (5): 1077–1094.

https://doi.org/10.1084/jem.138.5.1077

Published: 01 November 1973

View article titled, A SEQUENCE OF BIOCHEMICAL EVENTS IN THE ANTIGEN-INDUCED RELEASE OF CHEMICAL MEDIATORS FROM SENSITIZED HUMAN LUNG TISSUE

NARROW

Lineage-specific regulation of inducible and constitutive mast cells in allergic airway inflammation

Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s

Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes

Mast cell deficiency in Kit^W-sh mice does not impair antibody-mediated arthritis

Neutrophil-derived leukotriene B₄ is required for inflammatory arthritis

No audible wheezing : nuggets and conundrums from mouse asthma models

Prevention of Lipopolysaccharide-induced Microangiopathy by gp49B1 : Evidence for an Important Role for gp49B1 Expression on Neutrophils

Cysteinyl Leukotrienes and Uridine Diphosphate Induce Cytokine Generation by Human Mast Cells Through an Interleukin 4–regulated Pathway that Is Inhibited by Leukotriene Receptor Antagonists

Intestinal Mast Cell Progenitors Require CD49dβ7 (α4β7 Integrin) for Tissue-specific Homing

Increased Severity of Local and Systemic Anaphylactic Reactions in Gp49b1-Deficient Mice

The Diverse Roles of Mast Cells

T Helper Cell Type 2 Cytokines Coordinately Regulate Immunoglobulin E–Dependent Cysteinyl Leukotriene Production by Human Cord Blood–Derived Mast Cells: Profound Induction of Leukotriene C₄ Synthase Expression by Interleukin 4

T Helper Cell Type 2 Cytokine–Mediated Comitogenic Responses and Ccr3 Expression during Differentiation of Human Mast Cells in Vitro

Human Peripheral Blood Eosinophils Express a Functional c-kit Receptor for Stem Cell Factor that Stimulates Very Late Antigen 4 (VLA-4)–mediated Cell Adhesion to Fibronectin and Vascular Cell Adhesion Molecule 1 (VCAM-1)

FORMATION OF SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS IN HUMAN LUNG TISSUE AND CELLS BEFORE RELEASE

A NEUTROPHIL-DEPENDENT PATHWAY FOR THE GENERATION OF A NEUTRAL PEPTIDE MEDIATOR : PARTIAL CHARACTERIZATION OF COMPONENTS AND CONTROL BY α-1-ANTITRYPSIN

PROPERDIN FACTOR D : II. ACTIVATION TO D BY PROPERDIN

PROPERDIN FACTOR D: CHARACTERIZATION OF ITS ACTIVE SITE AND ISOLATION OF THE PRECURSOR FORM

FORMATION OF A HEMOLYTICALLY ACTIVE CELLULAR INTERMEDIATE BY THE INTERACTION BETWEEN PROPERDIN FACTORS B AND D AND THE ACTIVATED THIRD COMPONENT OF COMPLEMENT

A SEQUENCE OF BIOCHEMICAL EVENTS IN THE ANTIGEN-INDUCED RELEASE OF CHEMICAL MEDIATORS FROM SENSITIZED HUMAN LUNG TISSUE

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