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Journal Articles

P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection

In Special Collection:

Innate Immune Cells and Signaling 2023

J Exp Med (2022) 220 (1): e20220837.

https://doi.org/10.1084/jem.20220837

Published: 31 October 2022

View article titled, P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection

Includes: Supplementary data

Journal Articles

Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

In Special Collection:

T Cell Dysfunction, Cancer, and Infection

Mohammad Rashidian, Jessica R. Ingram, Michael Dougan, Anushka Dongre, Katherine A. Whang, Camille LeGall, Juan J. Cragnolini, Brian Bierie, Monica Gostissa, James Gorman, Gijsbert M. Grotenbreg, Atul Bhan, Robert A. Weinberg, Hidde L. Ploegh

J Exp Med (2017) 214 (8): 2243–2255.

https://doi.org/10.1084/jem.20161950

Published: 30 June 2017

View article titled, Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

Includes: Supplementary data

Journal Articles

Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83

Julia von Rohrscheidt, Elisabetta Petrozziello, Jelena Nedjic, Christine Federle, Lena Krzyzak, Hidde L. Ploegh, Satoshi Ishido, Alexander Steinkasserer, Ludger Klein

J Exp Med (2016) 213 (9): 1685–1694.

https://doi.org/10.1084/jem.20160316

Published: 08 August 2016

View article titled, Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83

Includes: Supplementary data

Journal Articles

A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly

Florian I. Schmidt, Alvin Lu, Jeff W. Chen, Jianbin Ruan, Catherine Tang, Hao Wu, Hidde L. Ploegh

J Exp Med (2016) 213 (5): 771–790.

https://doi.org/10.1084/jem.20151790

Published: 11 April 2016

View article titled, A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly

Includes: Supplementary data

Journal Articles

Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells

Ana M. Avalos, Angelina M. Bilate, Martin D. Witte, Albert K. Tai, Jiang He, Maria P. Frushicheva, Peter D. Thill, Friederike Meyer-Wentrup, Christopher S. Theile, Arup K. Chakraborty, Xiaowei Zhuang, Hidde L. Ploegh

J Exp Med (2014) 211 (2): 365–379.

https://doi.org/10.1084/jem.20131603

Published: 03 February 2014

View article titled, Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells

Includes: Supplementary data

Journal Articles

The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation

Boyoun Park, Eric Spooner, Brandy L. Houser, Jack L. Strominger, Hidde L. Ploegh

J Exp Med (2010) 207 (9): 2033–2041.

https://doi.org/10.1084/jem.20091793

Published: 16 August 2010

View article titled, The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation

Includes: Supplementary data

Journal Articles

Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes

Chih-Chi Andrew Hu, Stephanie K. Dougan, Sebastian Virreira Winter, Adrienne W. Paton, James C. Paton, Hidde L. Ploegh

J Exp Med (2009) 206 (11): 2429–2440.

https://doi.org/10.1084/jem.20090782

Published: 06 October 2009

View article titled, Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes

Includes: Supplementary data

Journal Articles

XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells

Boaz Tirosh, Neal N. Iwakoshi, Laurie H. Glimcher, Hidde L. Ploegh

J Exp Med (2005) 202 (4): 505–516.

https://doi.org/10.1084/jem.20050575

Published: 15 August 2005

View article titled, XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells

Journal Articles

Cotranslational endoplasmic reticulum assembly of FcεRI controls the formation of functional IgE-binding receptors

Edda Fiebiger, Domenico Tortorella, Marie-Helene Jouvin, Jean-Pierre Kinet, Hidde L. Ploegh

J Exp Med (2005) 201 (2): 267–277.

https://doi.org/10.1084/jem.20041384

Published: 10 January 2005

View article titled, Cotranslational endoplasmic reticulum assembly of FcεRI controls the formation of functional IgE-binding receptors

Journal Articles

Elimination In Vivo of Developing T Cells by Natural Killer Cells

Eckart Schott, Roberto Bonasio, Hidde L. Ploegh

J Exp Med (2003) 198 (8): 1213–1224.

https://doi.org/10.1084/jem.20030918

Published: 20 October 2003

View article titled, Elimination In Vivo of Developing T Cells by Natural Killer Cells

Journal Articles

Invariant Chain Controls the Activity of Extracellular Cathepsin L

Edda Fiebiger, René Maehr, José Villadangos, Ekkehard Weber, Ann Erickson, Elizabeth Bikoff, Hidde L. Ploegh, Ana-Maria Lennon-Duménil

J Exp Med (2002) 196 (9): 1263–1270.

https://doi.org/10.1084/jem.20020762

Published: 04 November 2002

View article titled, Invariant Chain Controls the Activity of Extracellular Cathepsin L

Journal Articles

Analysis of Protease Activity in Live Antigen-presenting Cells Shows Regulation of the Phagosomal Proteolytic Contents During Dendritic Cell Activation

Ana-Maria Lennon-Duménil, Arnold H. Bakker, René Maehr, Edda Fiebiger, Herman S. Overkleeft, Mario Rosemblatt, Hidde L. Ploegh, Cécile Lagaudrière-Gesbert

J Exp Med (2002) 196 (4): 529–540.

https://doi.org/10.1084/jem.20020327

Published: 19 August 2002

View article titled, Analysis of Protease Activity in Live Antigen-presenting Cells Shows Regulation of the Phagosomal Proteolytic Contents During Dendritic Cell Activation

Journal Articles

Role for Cathepsin F in Invariant Chain Processing and Major Histocompatibility Complex Class II Peptide Loading by Macrophages

Guo-Ping Shi, Rebecca A.R. Bryant, Richard Riese, Steven Verhelst, Christoph Driessen, Zhenqiang Li, Dieter Bromme, Hidde L. Ploegh, Harold A. Chapman

J Exp Med (2000) 191 (7): 1177–1186.

https://doi.org/10.1084/jem.191.7.1177

Published: 03 April 2000

View article titled, Role for Cathepsin F in Invariant Chain Processing and Major Histocompatibility Complex Class II Peptide Loading by Macrophages

Journal Articles

Trophoblast Class I Major Histocompatibility Complex (MHC) Products Are Resistant to Rapid Degradation Imposed by the Human Cytomegalovirus (HCMV) Gene Products US2 and US11

Danny J. Schust, Domenico Tortorella, Jörg Seebach, Cindy Phan, Hidde L. Ploegh

J Exp Med (1998) 188 (3): 497–503.

https://doi.org/10.1084/jem.188.3.497

Published: 03 August 1998

View article titled, Trophoblast Class I Major Histocompatibility Complex (MHC) Products Are Resistant to Rapid Degradation Imposed by the Human Cytomegalovirus (HCMV) Gene Products US2 and US11

Journal Articles

Degradation of Mouse Invariant Chain: Roles of Cathepsins S and D and the Influence of Major Histocompatibility Complex Polymorphism

José A. Villadangos, Richard J. Riese, Christoph Peters, Harold A. Chapman, Hidde L. Ploegh

J Exp Med (1997) 186 (4): 549–560.

https://doi.org/10.1084/jem.186.4.549

Published: 18 August 1997

View article titled, Degradation of Mouse Invariant Chain: Roles of Cathepsins S and D and the Influence of Major Histocompatibility Complex Polymorphism

Journal Articles

In Vitro Translation and Assembly of a Complete T Cell Receptor–CD3 Complex

Johannes B. Huppa, Hidde L. Ploegh

J Exp Med (1997) 186 (3): 393–403.

https://doi.org/10.1084/jem.186.3.393

Published: 04 August 1997

View article titled, In Vitro Translation and Assembly of a Complete T Cell Receptor–CD3 Complex

Journal Articles

The Active Site of ICP47, a Herpes Simplex Virus–encoded Inhibitor of the Major Histocompatibility Complex (MHC)-encoded Peptide Transporter Associated with Antigen Processing (TAP), Maps to the NH₂-terminal 35 Residues

Begoña Galocha, Ann Hill, Barbara C. Barnett, Aidan Dolan, Alejandra Raimondi, Richard F. Cook, Joseph Brunner, Duncan J. McGeoch, Hidde L. Ploegh

J Exp Med (1997) 185 (9): 1565–1572.

https://doi.org/10.1084/jem.185.9.1565

Published: 05 May 1997

View article titled, The Active Site of ICP47, a Herpes Simplex Virus–encoded Inhibitor of the Major Histocompatibility Complex (MHC)-encoded Peptide Transporter Associated with Antigen Processing (TAP), Maps to the NH<sub>2</sub>-terminal 35 Residues

Journal Articles

Intermediates in the Assembly and Degradation of Class I Major Histocompatibility Complex (MHC) Molecules Probed with Free Heavy Chain–specific Monoclonal Antibodies

Robert P. Machold, Hidde L. Ploegh

J Exp Med (1996) 184 (6): 2251–2260.

https://doi.org/10.1084/jem.184.6.2251

Published: 01 December 1996

View article titled, Intermediates in the Assembly and Degradation of Class I Major Histocompatibility Complex (MHC) Molecules Probed with Free Heavy Chain–specific Monoclonal Antibodies

NARROW

P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection

Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83

A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly

Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells

The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation

Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes

XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells

Cotranslational endoplasmic reticulum assembly of FcεRI controls the formation of functional IgE-binding receptors

Elimination In Vivo of Developing T Cells by Natural Killer Cells

Invariant Chain Controls the Activity of Extracellular Cathepsin L

Analysis of Protease Activity in Live Antigen-presenting Cells Shows Regulation of the Phagosomal Proteolytic Contents During Dendritic Cell Activation

Role for Cathepsin F in Invariant Chain Processing and Major Histocompatibility Complex Class II Peptide Loading by Macrophages

Trophoblast Class I Major Histocompatibility Complex (MHC) Products Are Resistant to Rapid Degradation Imposed by the Human Cytomegalovirus (HCMV) Gene Products US2 and US11

Degradation of Mouse Invariant Chain: Roles of Cathepsins S and D and the Influence of Major Histocompatibility Complex Polymorphism

In Vitro Translation and Assembly of a Complete T Cell Receptor–CD3 Complex

The Active Site of ICP47, a Herpes Simplex Virus–encoded Inhibitor of the Major Histocompatibility Complex (MHC)-encoded Peptide Transporter Associated with Antigen Processing (TAP), Maps to the NH₂-terminal 35 Residues

Intermediates in the Assembly and Degradation of Class I Major Histocompatibility Complex (MHC) Molecules Probed with Free Heavy Chain–specific Monoclonal Antibodies

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