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Matthew D. Scharff
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Journal Articles

The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination

Richard Chahwan, Johanna M.M. van Oers, Elena Avdievich, Chunfang Zhao, Winfried Edelmann, Matthew D. Scharff, Sergio Roa
Journal: Journal of Experimental Medicine
J Exp Med (2012) 209 (4): 671–678.
https://doi.org/10.1084/jem.20111531
Published: 26 March 2012
View article titled, The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination
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Journal Articles

A requirement for FcγR in antibody-mediated bacterial toxin neutralization

Nareen Abboud, Siu-Kei Chow, Carolyn Saylor, Alena Janda, Jeffery V. Ravetch, Matthew D. Scharff, Arturo Casadevall
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (11): 2395–2405.
https://doi.org/10.1084/jem.20100995
Published: 04 October 2010
View article titled, A requirement for FcγR in antibody-mediated bacterial toxin neutralization
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Journal Articles

Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation

Diana Ronai, Maria D. Iglesias-Ussel, Manxia Fan, Ziqiang Li, Alberto Martin, Matthew D. Scharff
Journal: Journal of Experimental Medicine
J Exp Med (2007) 204 (1): 181–190.
https://doi.org/10.1084/jem.20062032
Published: 16 January 2007
View article titled, Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation
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Includes: Supplementary data
Journal Articles

Identifying protein–protein interactions in somatic hypermutation

Myron F. Goodman, Matthew D. Scharff
Journal: Journal of Experimental Medicine
J Exp Med (2005) 201 (4): 493–496.
https://doi.org/10.1084/jem.20050161
Published: 14 February 2005
View article titled, Identifying protein–protein interactions in somatic hypermutation
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Journal Articles

Examination of Msh6- and Msh3-deficient Mice in Class Switching Reveals Overlapping and Distinct Roles of MutS Homologues in Antibody Diversification

Ziqiang Li, Stefan J. Scherer, Diana Ronai, Maria D. Iglesias-Ussel, Jonathan U. Peled, Philip D. Bardwell, Min Zhuang, KyeRyoung Lee, Alberto Martin, Winfried Edelmann, Matthew D. Scharff
Journal: Journal of Experimental Medicine
J Exp Med (2004) 200 (1): 47–59.
https://doi.org/10.1084/jem.20040355
Published: 06 July 2004
View article titled, Examination of Msh6- and Msh3-deficient Mice in Class Switching Reveals Overlapping and Distinct Roles of MutS Homologues in Antibody Diversification
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Includes: Supplementary data
Journal Articles

Msh2 ATPase Activity Is Essential for Somatic Hypermutation at A-T Basepairs and for Efficient Class Switch Recombination

Alberto Martin, Ziqiang Li, Diana P. Lin, Philip D. Bardwell, Maria D. Iglesias-Ussel, Winfried Edelmann, Matthew D. Scharff
Journal: Journal of Experimental Medicine
J Exp Med (2003) 198 (8): 1171–1178.
https://doi.org/10.1084/jem.20030880
Published: 20 October 2003
View article titled, Msh2 ATPase Activity Is Essential for Somatic Hypermutation at A-T Basepairs and for Efficient Class Switch Recombination
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Includes: Supplementary data
Journal Articles

Error-Prone Candidates Vie for Somatic Mutation

Vladimir Poltoratsky, Myron F. Goodman, Matthew D. Scharff
Journal: Journal of Experimental Medicine
J Exp Med (2000) 192 (10): F27–F30.
https://doi.org/10.1084/jem.192.10.F27
Published: 20 November 2000
View article titled, Error-Prone Candidates Vie for Somatic Mutation
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Journal Articles

Somatic Hypermutation in Muts Homologue (Msh)3-, Msh6-, and Msh3/Msh6-Deficient Mice Reveals a Role for the Msh2–Msh6 Heterodimer in Modulating the Base Substitution Pattern

Margrit Wiesendanger, Burkhard Kneitz, Winfried Edelmann, Matthew D. Scharff
Journal: Journal of Experimental Medicine
J Exp Med (2000) 191 (3): 579–584.
https://doi.org/10.1084/jem.191.3.579
Published: 07 February 2000
View article titled, Somatic Hypermutation in Muts Homologue (Msh)3-, Msh6-, and Msh3/Msh6-Deficient Mice Reveals a Role for the Msh2–Msh6 Heterodimer in Modulating the Base Substitution Pattern
Open the PDF for Somatic Hypermutation in Muts Homologue (Msh)3-, Msh6-, and Msh3/Msh6-Deficient Mice Reveals a Role for the Msh2–Msh6 Heterodimer in Modulating the Base Substitution Pattern in another window
Journal Articles

Antibody-mediated Modulation of Cryptococcus neoformans Infection Is Dependent on Distinct Fc Receptor Functions and IgG Subclasses

RuiRong Yuan, Raphael Clynes, Jin Oh, Jeffrey V. Ravetch, Matthew D. Scharff
Journal: Journal of Experimental Medicine
J Exp Med (1998) 187 (4): 641–648.
https://doi.org/10.1084/jem.187.4.641
Published: 16 February 1998
View article titled, Antibody-mediated Modulation of <em>Cryptococcus neoformans</em> Infection Is Dependent on Distinct Fc Receptor Functions and IgG Subclasses
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Journal Articles

Epitope Location in the Cryptococcus neoformans Capsule Is a Determinant of Antibody Efficacy

Gabriel Nussbaum, Wendy Cleare, Arturo Casadevall, Matthew D. Scharff, Philippe Valadon
Journal: Journal of Experimental Medicine
J Exp Med (1997) 185 (4): 685–694.
https://doi.org/10.1084/jem.185.4.685
Published: 17 February 1997
View article titled, Epitope Location in the <em>Cryptococcus neoformans</em> Capsule Is a Determinant of Antibody Efficacy
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Journal Articles

The Promotion of  V Region Hypermutation

Matthew D. Scharff, Vladimir Poltoratsky, Nancy S. Green
Journal: Journal of Experimental Medicine
J Exp Med (1997) 185 (2): 185–188.
https://doi.org/10.1084/jem.185.2.185
Published: 20 January 1997
View article titled, The Promotion of  V Region Hypermutation
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Journal Articles

INDEPENDENT SYNTHESIS OF LIGHT AND HEAVY CHAINS : Quantitation of Light-Chain Production by Mouse Myeloma Variants

Reuven Laskov, Matthew D. Scharff
Journal: Journal of Experimental Medicine
J Exp Med (1974) 140 (4): 1112–1116.
https://doi.org/10.1084/jem.140.4.1112
Published: 01 October 1974
View article titled, INDEPENDENT SYNTHESIS OF LIGHT AND HEAVY CHAINS : <subtitle>Quantitation of Light-Chain Production by Mouse Myeloma Variants </subtitle>
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Journal Articles

SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : III. ASSEMBLY OF THE THREE SUBCLASSES OF IGG

Reuben Baumal, Michael Potter, Matthew D. Scharff
Journal: Journal of Experimental Medicine
J Exp Med (1971) 134 (5): 1316–1334.
https://doi.org/10.1084/jem.134.5.1316
Published: 01 November 1971
View article titled, SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : <subtitle>III. A<sc>SSEMBLY OF THE</sc> T<sc>HREE</sc> S<sc>UBCLASSES OF</sc> I<sc>G</sc>G </subtitle>
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Journal Articles

SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : I. ADAPTATION OF THE MERWIN PLASMA CELL TUMOR-11 TO CULTURE, CLONING, AND CHARACTERIZATION OF GAMMA GLOBULIN SUBUNITS

Reuven Laskov, Matthew D. Scharff
Journal: Journal of Experimental Medicine
J Exp Med (1970) 131 (3): 515–541.
https://doi.org/10.1084/jem.131.3.515
Published: 01 March 1970
View article titled, SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : <subtitle>I. A<sc>DAPTATION OF THE</sc> M<sc>ERWIN</sc> P<sc>LASMA</sc> C<sc>ELL</sc> T<sc>UMOR</sc>-11 <sc>TO</sc> C<sc>ULTURE</sc>, C<sc>LONING, AND</sc> C<sc>HARACTERIZATION OF</sc> G<sc>AMMA</sc> G<sc>LOBULIN</sc> S<sc>UBUNITS </sc></subtitle>
Open the PDF for SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : <subtitle>I. A<sc>DAPTATION OF THE</sc> M<sc>ERWIN</sc> P<sc>LASMA</sc> C<sc>ELL</sc> T<sc>UMOR</sc>-11 <sc>TO</sc> C<sc>ULTURE</sc>, C<sc>LONING, AND</sc> C<sc>HARACTERIZATION OF</sc> G<sc>AMMA</sc> G<sc>LOBULIN</sc> S<sc>UBUNITS </sc></subtitle> in another window