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Journal Articles

Four keys to unlock IgG

Falk Nimmerjahn, Jeffrey V. Ravetch

J Exp Med (2021) 218 (3): e20201753.

https://doi.org/10.1084/jem.20201753

Published: 16 February 2021

View article titled, Four keys to unlock IgG

Journal Articles

Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo

In Special Collection:

Antibodies at the Forefront of Disease Treatment , COVID-19: From Basic Science to Therapeutics

Alexandra Schäfer, Frauke Muecksch, Julio C.C. Lorenzi, Sarah R. Leist, Melissa Cipolla, Stylianos Bournazos, Fabian Schmidt, Rachel M. Maison, Anna Gazumyan, David R. Martinez, Ralph S. Baric, Davide F. Robbiani, Theodora Hatziioannou, Jeffrey V. Ravetch, Paul D. Bieniasz, Richard A. Bowen, Michel C. Nussenzweig, Timothy P. Sheahan

J Exp Med (2020) 218 (3): e20201993.

https://doi.org/10.1084/jem.20201993

Published: 19 November 2020

View article titled, Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo

Journal Articles

DC subset–specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo

Christian H.K. Lehmann, Anna Baranska, Gordon F. Heidkamp, Lukas Heger, Kirsten Neubert, Jennifer J. Lühr, Alana Hoffmann, Katharina C. Reimer, Christin Brückner, Simone Beck, Michaela Seeling, Melissa Kießling, Didier Soulat, Anne B. Krug, Jeffrey V. Ravetch, Jeanette H.W. Leusen, Falk Nimmerjahn, Diana Dudziak

J Exp Med (2017) 214 (5): 1509–1528.

https://doi.org/10.1084/jem.20160951

Published: 07 April 2017

View article titled, DC subset–specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo

Includes: Supplementary data

Journal Articles

The role of Fc–FcγR interactions in IgG-mediated microbial neutralization

Stylianos Bournazos, David J. DiLillo, Jeffrey V. Ravetch

J Exp Med (2015) 212 (9): 1361–1369.

https://doi.org/10.1084/jem.20151267

Published: 17 August 2015

View article titled, The role of Fc–FcγR interactions in IgG-mediated microbial neutralization

Journal Articles

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma

Tyler R. Simpson, Fubin Li, Welby Montalvo-Ortiz, Manuel A. Sepulveda, Katharina Bergerhoff, Frederick Arce, Claire Roddie, Jake Y. Henry, Hideo Yagita, Jedd D. Wolchok, Karl S. Peggs, Jeffrey V. Ravetch, James P. Allison, Sergio A. Quezada

J Exp Med (2013) 210 (9): 1695–1710.

https://doi.org/10.1084/jem.20130579

Published: 29 July 2013

View article titled, Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma

Journal Articles

Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases

Ana V. Miletic, Amy N. Anzelon-Mills, David M. Mills, Sidne A. Omori, Irene M. Pedersen, Dong-Mi Shin, Jeffrey V. Ravetch, Silvia Bolland, Herbert C. Morse, III, Robert C. Rickert

J Exp Med (2010) 207 (11): 2407–2420.

https://doi.org/10.1084/jem.20091962

Published: 18 October 2010

View article titled, Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases

Includes: Supplementary data

Journal Articles

Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Kavita M. Dhodapkar, Devi Banerjee, John Connolly, Anjli Kukreja, Elyana Matayeva, Maria Concetta Veri, Jeffrey V. Ravetch, Ralph M. Steinman, Madhav V. Dhodapkar

J Exp Med (2007) 204 (10): 2489.

https://doi.org/10.1084/jem.20062545082307c

Published: 01 October 2007

View article titled, Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Journal Articles

Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus

Fredrik Wermeling, Yunying Chen, Timo Pikkarainen, Annika Scheynius, Ola Winqvist, Shozo Izui, Jeffrey V. Ravetch, Karl Tryggvason, Mikael C.I. Karlsson

J Exp Med (2007) 204 (10): 2259–2265.

https://doi.org/10.1084/jem.20070600

Published: 24 September 2007

View article titled, Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus

Includes: Supplementary data

Journal Articles

Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Kavita M. Dhodapkar, Devi Banerjee, John Connolly, Anjli Kukreja, Elyana Matayeva, Maria Concetta Veri, Jeffrey V. Ravetch, Ralph M. Steinman, Madhav V. Dhodapkar

J Exp Med (2007) 204 (10): 2494.

https://doi.org/10.1084/jem.2006254508232007c

Published: 04 September 2007

View article titled, Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Journal Articles

Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Kavita M. Dhodapkar, Devi Banerjee, John Connolly, Anjli Kukreja, Elyana Matayeva, Maria Concetta Veri, Jeffrey V. Ravetch, Ralph M. Steinman, Madhav V. Dhodapkar

J Exp Med (2007) 204 (6): 1359–1369.

https://doi.org/10.1084/jem.20062545

Published: 14 May 2007

View article titled, Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Includes: Supplementary data

Journal Articles

The antiinflammatory activity of IgG: the intravenous IgG paradox

Falk Nimmerjahn, Jeffrey V. Ravetch

J Exp Med (2007) 204 (1): 11–15.

https://doi.org/10.1084/jem.20061788

Published: 16 January 2007

View article titled, The antiinflammatory activity of IgG: the intravenous IgG paradox

Journal Articles

Selective dysregulation of the FcγIIB receptor on memory B cells in SLE

Meggan Mackay, Anfisa Stanevsky, Tao Wang, Cynthia Aranow, Margaret Li, Scott Koenig, Jeffrey V. Ravetch, Betty Diamond

J Exp Med (2006) 203 (9): 2157–2164.

https://doi.org/10.1084/jem.20051503

Published: 21 August 2006

View article titled, Selective dysregulation of the FcγIIB receptor on memory B cells in SLE

Journal Articles

Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors

Yoshikatsu Kaneko, Falk Nimmerjahn, Michael P. Madaio, Jeffrey V. Ravetch

J Exp Med (2006) 203 (3): 789–797.

https://doi.org/10.1084/jem.20051900

Published: 06 March 2006

View article titled, Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors

Includes: Supplementary data

Journal Articles

TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE

Marc Ehlers, Hidehiro Fukuyama, Tracy L. McGaha, Alan Aderem, Jeffrey V. Ravetch

J Exp Med (2006) 203 (3): 553–561.

https://doi.org/10.1084/jem.20052438

Published: 21 February 2006

View article titled, TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE

Includes: Supplementary data

Journal Articles

Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b^{− / −}Pdcd1^{− / −} mice

Taku Okazaki, Yumi Otaka, Jian Wang, Hiroshi Hiai, Toshiyuki Takai, Jeffrey V. Ravetch, Tasuku Honjo

J Exp Med (2005) 202 (12): 1643–1648.

https://doi.org/10.1084/jem.20051984

Published: 13 December 2005

View article titled, Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b − / − Pdcd1 − / − mice

Journal Articles

The Innate Mononuclear Phagocyte Network Depletes B Lymphocytes through Fc Receptor–dependent Mechanisms during Anti-CD20 Antibody Immunotherapy

Junji Uchida, Yasuhito Hamaguchi, Julie A. Oliver, Jeffrey V. Ravetch, Jonathan C. Poe, Karen M. Haas, Thomas F. Tedder

J Exp Med (2004) 199 (12): 1659–1669.

https://doi.org/10.1084/jem.20040119

Published: 21 June 2004

View article titled, The Innate Mononuclear Phagocyte Network Depletes B Lymphocytes through Fc Receptor–dependent Mechanisms during Anti-CD20 Antibody Immunotherapy

Journal Articles

Macrophages Control the Retention and Trafficking of B Lymphocytes in the Splenic Marginal Zone

Mikael C.I. Karlsson, Rodolphe Guinamard, Silvia Bolland, Marko Sankala, Ralph M. Steinman, Jeffrey V. Ravetch

J Exp Med (2003) 198 (2): 333–340.

https://doi.org/10.1084/jem.20030684

Published: 21 July 2003

View article titled, Macrophages Control the Retention and Trafficking of B Lymphocytes in the Splenic Marginal Zone

Journal Articles

Inducing Tumor Immunity through the Selective Engagement of Activating Fcγ Receptors on Dendritic Cells

Alexis M. Kalergis, Jeffrey V. Ravetch

J Exp Med (2002) 195 (12): 1653–1659.

https://doi.org/10.1084/jem.20020338

Published: 17 June 2002

View article titled, Inducing Tumor Immunity through the Selective Engagement of Activating Fcγ Receptors on Dendritic Cells

Journal Articles

Genetic Modifiers of Systemic Lupus Erythematosus in FcγRIIB^−/− Mice

Silvia Bolland, Young-Sun Yim, Katalin Tus, Edward K. Wakeland, Jeffrey V. Ravetch

J Exp Med (2002) 195 (9): 1167–1174.

https://doi.org/10.1084/jem.20020165

Published: 29 April 2002

View article titled, Genetic Modifiers of Systemic Lupus Erythematosus in FcγRIIB−/− Mice

Journal Articles

Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo

Daniel Hawiger, Kayo Inaba, Yair Dorsett, Ming Guo, Karsten Mahnke, Miguel Rivera, Jeffrey V. Ravetch, Ralph M. Steinman, Michel C. Nussenzweig

J Exp Med (2001) 194 (6): 769–780.

https://doi.org/10.1084/jem.194.6.769

Published: 17 September 2001

View article titled, Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo

NARROW

Four keys to unlock IgG

Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo

DC subset–specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo

The role of Fc–FcγR interactions in IgG-mediated microbial neutralization

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma

Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases

Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus

Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

The antiinflammatory activity of IgG: the intravenous IgG paradox

Selective dysregulation of the FcγIIB receptor on memory B cells in SLE

Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors

TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE

Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b^{− / −}Pdcd1^{− / −} mice

The Innate Mononuclear Phagocyte Network Depletes B Lymphocytes through Fc Receptor–dependent Mechanisms during Anti-CD20 Antibody Immunotherapy

Macrophages Control the Retention and Trafficking of B Lymphocytes in the Splenic Marginal Zone

Inducing Tumor Immunity through the Selective Engagement of Activating Fcγ Receptors on Dendritic Cells

Genetic Modifiers of Systemic Lupus Erythematosus in FcγRIIB^−/− Mice

Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo

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