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Volume 190, Issue 4

16 August 1999

Cover Image

Cover Image

Cover picture: Radiographic analysis revealed that compared with streptococcal cell wallinjected animals, which exhibit overt erosion of cartilage and bone (left), full-length recombinant rat secretory leukocyte protease inhibitortreated animals had minimal pathological changes with only mild soft tissue swelling (right). See related article in this issue by Song et al., pp. 535542.

Table of Contents

Editorial Board

ISSN 0022-1007

EISSN 1540-9538

In this Issue

Commentary

Article

Brief Definitive Report

Commentary

The Role of Cyclooxygenase Inhibition in the Antineoplastic Effects of Nonsteroidal Antiinflammatory Drugs (Nsaids)

Steven J. Shiff,Basil Rigas

View Articletitled, The Role of Cyclooxygenase Inhibition in the Antineoplastic Effects of Nonsteroidal Antiinflammatory Drugs (Nsaids)

Article

Malignant Transformation and Antineoplastic Actions of Nonsteroidal Antiinflammatory Drugs (Nsaids) on Cyclooxygenase-Null Embryo Fibroblasts

Xinping Zhang,Scott G. Morham,Robert Langenbach,Donald A. Young

View Articletitled, Malignant Transformation and Antineoplastic Actions of Nonsteroidal Antiinflammatory Drugs (Nsaids) on Cyclooxygenase-Null Embryo Fibroblasts

Expression Levels of B Cell Surface Immunoglobulin Regulate Efficiency of Allelic Exclusion and Size of Autoreactive B-1 Cell Compartment

Norihiko Watanabe,Sazuku Nisitani,Koichi Ikuta,Misao Suzuki,Tsutomu Chiba,Tasuku Honjo

View Articletitled, Expression Levels of B Cell Surface Immunoglobulin Regulate Efficiency of Allelic Exclusion and Size of Autoreactive B-1 Cell Compartment

B Cell Antigen Receptor Specificity and Surface Density Together Determine B-1 versus B-2 Cell Development

Kong-Peng Lam,Klaus Rajewsky

View Articletitled, B Cell Antigen Receptor Specificity and Surface Density Together Determine B-1 versus B-2 Cell Development

Direct Evidence for Thymic Function in Adult Humans

Jean-François Poulin,Mohan N. Viswanathan,Jeffrey M. Harris,Krishna V. Komanduri,Eric Wieder,Nancy Ringuette,Morgan Jenkins,Joseph M. McCune,Rafick-Pierre Sékaly

View Articletitled, Direct Evidence for Thymic Function in Adult Humans

Expression of Cd28 and Cd86 by Human Eosinophils and Role in the Secretion of Type 1 Cytokines (Interleukin 2 and Interferon γ): Inhibition by Immunoglobulin a Complexes

Gaëtane Woerly,Nadine Roger,Sylvie Loiseau,David Dombrowicz,André Capron,Monique Capron

View Articletitled, Expression of Cd28 and Cd86 by Human Eosinophils and Role in the Secretion of Type 1 Cytokines (Interleukin 2 and Interferon γ): Inhibition by Immunoglobulin a Complexes

Novel Point Mutation in the Extracellular Domain of the Granulocyte Colony-Stimulating Factor (G-Csf) Receptor in a Case of Severe Congenital Neutropenia Hyporesponsive to G-Csf Treatment

Alister C. Ward,Yvette M. van Aesch,Judith Gits,Anita M. Schelen,John P. de Koning,Daphne van Leeuwen,Melvin H. Freedman,Ivo P. Touw

View Articletitled, Novel Point Mutation in the Extracellular Domain of the Granulocyte Colony-Stimulating Factor (G-Csf) Receptor in a Case of Severe Congenital Neutropenia Hyporesponsive to G-Csf Treatment

Internalization of Monomeric Lipopolysaccharide Occurs after Transfer Out of Cell Surface Cd14

Thierry Vasselon,Eric Hailman,Rolf Thieringer,Patricia A. Detmers

View Articletitled, Internalization of Monomeric Lipopolysaccharide Occurs after Transfer Out of Cell Surface Cd14

Transport of Bacterial Lipopolysaccharide to the Golgi Apparatus

Nathalie Thieblemont,Samuel D. Wright

View Articletitled, Transport of Bacterial Lipopolysaccharide to the Golgi Apparatus

Secretory Leukocyte Protease Inhibitor Suppresses the Inflammation and Joint Damage of Bacterial Cell Wall–Induced Arthritis

Xiao-yu Song,Li Zeng,Wenwen Jin,John Thompson,Diane E. Mizel,Ke-jian Lei,R.C. Billinghurst,A. Robin Poole,Sharon M. Wahl

View Articletitled, Secretory Leukocyte Protease Inhibitor Suppresses the Inflammation and Joint Damage of Bacterial Cell Wall–Induced Arthritis

Antigen-Specific Signaling by a Soluble, Dimeric Peptide/Major Histocompatibility Complex Class II/Fc Chimera Leading to T Helper Cell Type 2 Differentiation

Sofia Casares,Cong S. Zong,Dorel L. Radu,Alexander Miller,Constantin A. Bona,Teodor-Doru Brumeanu

View Articletitled, Antigen-Specific Signaling by a Soluble, Dimeric Peptide/Major Histocompatibility Complex Class II/Fc Chimera Leading to T Helper Cell Type 2 Differentiation

Endothelial Cells Modify the Costimulatory Capacity of Transmigrating Leukocytes and Promote Cd28-Mediated Cd4⁺ T Cell Alloactivation

Mark D. Denton,Christopher S. Geehan,Steve I. Alexander,Mohamed H. Sayegh,David M. Briscoe

View Articletitled, Endothelial Cells Modify the Costimulatory Capacity of Transmigrating Leukocytes and Promote Cd28-Mediated Cd4+ T Cell Alloactivation

Epstein-Barr Virus–Infected Resting Memory B Cells, Not Proliferating Lymphoblasts, Accumulate in the Peripheral Blood of Immunosuppressed Patients

Gregory J. Babcock,Lisa L. Decker,Richard B. Freeman,David A. Thorley-Lawson

View Articletitled, Epstein-Barr Virus–Infected Resting Memory B Cells, Not Proliferating Lymphoblasts, Accumulate in the Peripheral Blood of Immunosuppressed Patients

Triggering a Second T Cell Receptor on Diabetogenic T Cells Can Prevent Induction of Diabetes

Gianluca Fossati,Anne Cooke,Ruby Quartey Papafio,Kathryn Haskins,Brigitta Stockinger

View Articletitled, Triggering a Second T Cell Receptor on Diabetogenic T Cells Can Prevent Induction of Diabetes

Brief Definitive Report

The Major Receptor for C-Reactive Protein on Leukocytes Is Fcγ Receptor II

Dwaipayan Bharadwaj,Mary-Pat Stein,Michael Volzer,Carolyn Mold,Terry W. Du Clos

View Articletitled, The Major Receptor for C-Reactive Protein on Leukocytes Is Fcγ Receptor II

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Interstitial macrophages are a focus of viral takeover and inflammation in COVID-19 initiation in human lung

Helper T cell immunity in humans with inherited CD4 deficiency

TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation

ICOS costimulation in combination with CTLA-4 blockade remodels tumor-associated macrophages toward an antitumor phenotype

Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity

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