Page 1 | Search Results | Journal of Experimental Medicine

Skip Nav Destination

1-20 of 41

Sort by

Sort Order Select

Journal Articles

miR-23∼27∼24 clusters control effector T cell differentiation and function

Sunglim Cho, Cheng-Jang Wu, Tomoharu Yasuda, Leilani O. Cruz, Aly Azeem Khan, Ling-Li Lin, Duc T. Nguyen, Marina Miller, Hyang-Mi Lee, Ming-Ling Kuo, David H. Broide, Klaus Rajewsky, Alexander Y. Rudensky, Li-Fan Lu

J Exp Med (2016) 213 (2): 235–249.

https://doi.org/10.1084/jem.20150990

Published: 01 February 2016

View article titled, miR-23∼27∼24 clusters control effector T cell differentiation and function

Includes: Supplementary data

Journal Articles

Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes

Taras Kreslavsky, Hye-Jung Kim, Sergei B. Koralov, Dvora Ghitza, Thorsten Buch, Harvey Cantor, Klaus Rajewsky, Harald von Boehmer

J Exp Med (2013) 210 (10): 1911–1918.

https://doi.org/10.1084/jem.20130876

Published: 26 August 2013

View article titled, Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes

Includes: Supplementary data

Journal Articles

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory

Tomohiro Kaji, Akiko Ishige, Masaki Hikida, Junko Taka, Atsushi Hijikata, Masato Kubo, Takeshi Nagashima, Yoshimasa Takahashi, Tomohiro Kurosaki, Mariko Okada, Osamu Ohara, Klaus Rajewsky, Toshitada Takemori

J Exp Med (2012) 209 (11): 2079–2097.

https://doi.org/10.1084/jem.20120127

Published: 01 October 2012

View article titled, Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory

Includes: Supplementary data

Journal Articles

Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination

Duane R. Wesemann, Jennifer M. Magee, Cristian Boboila, Dinis Pedro Calado, Michael P. Gallagher, Andrew J. Portuguese, John P. Manis, Xiaolong Zhou, Mike Recher, Klaus Rajewsky, Luigi D. Notarangelo, Frederick W. Alt

J Exp Med (2011) 208 (13): 2733–2746.

https://doi.org/10.1084/jem.20111155

Published: 05 December 2011

View article titled, Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination

Journal Articles

CIN85 drives B cell responses by linking BCR signals to the canonical NF-κB pathway

Kohei Kometani, Takayuki Yamada, Yoshiteru Sasaki, Tadashi Yokosuka, Takashi Saito, Klaus Rajewsky, Masamichi Ishiai, Masaki Hikida, Tomohiro Kurosaki

J Exp Med (2011) 208 (7): 1447–1457.

https://doi.org/10.1084/jem.20102665

Published: 27 June 2011

View article titled, CIN85 drives B cell responses by linking BCR signals to the canonical NF-κB pathway

Includes: Supplementary data

Journal Articles

PLC-γ2 is essential for formation and maintenance of memory B cells

Masaki Hikida, Stefano Casola, Noriko Takahashi, Tomohiro Kaji, Toshitada Takemori, Klaus Rajewsky, Tomohiro Kurosaki

J Exp Med (2009) 206 (3): 681–689.

https://doi.org/10.1084/jem.20082100

Published: 09 March 2009

View article titled, PLC-γ2 is essential for formation and maintenance of memory B cells

Includes: Supplementary data

Journal Articles

Polζ ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability

Dominik Schenten, Sven Kracker, Gloria Esposito, Sonia Franco, Ulf Klein, Michael Murphy, Frederick W. Alt, Klaus Rajewsky

J Exp Med (2009) 206 (2): 477–490.

https://doi.org/10.1084/jem.20080669

Published: 09 February 2009

View article titled, Polζ ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability

Includes: Supplementary data

Journal Articles

Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching

Jing H. Wang, Frederick W. Alt, Monica Gostissa, Abhishek Datta, Michael Murphy, Marat B. Alimzhanov, Kristen M. Coakley, Klaus Rajewsky, John P. Manis, Catherine T. Yan

J Exp Med (2008) 205 (13): 3079–3090.

https://doi.org/10.1084/jem.20082271

Published: 08 December 2008

View article titled, Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching

Includes: Supplementary data

Journal Articles

Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-κB pathway and promotes lymphomagenesis

Cornelia Hömig-Hölzel, Caroline Hojer, Julia Rastelli, Stefano Casola, Lothar J. Strobl, Werner Müller, Leticia Quintanilla-Martinez, Andreas Gewies, Jürgen Ruland, Klaus Rajewsky, Ursula Zimber-Strobl

J Exp Med (2008) 205 (6): 1317–1329.

https://doi.org/10.1084/jem.20080238

Published: 19 May 2008

View article titled, Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-κB pathway and promotes lymphomagenesis

Includes: Supplementary data

Journal Articles

IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Igα/β

Ari Waisman, Manfred Kraus, Jane Seagal, Snigdha Ghosh, Doron Melamed, Jian Song, Yoshiteru Sasaki, Sabine Classen, Claudia Lutz, Frank Brombacher, Lars Nitschke, Klaus Rajewsky

J Exp Med (2007) 204 (4): 747–758.

https://doi.org/10.1084/jem.20062024

Published: 09 April 2007

View article titled, IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Igα/β

Includes: Supplementary data

Journal Articles

Retraction

Niklas Feldhahn, Ines Schwering, Sanggyu Lee, Maria Wartenberg, Florian Klein, Hui Wang, Guolin Zhou, San Ming Wang, Janet D. Rowley, Jürgen Hescheler, Martin Krönke, Klaus Rajewsky, Ralf Küppers, Markus Müschen

J Exp Med (2006) 203 (12): 2779.

https://doi.org/10.1084/jem.2002088173106c

Published: 30 October 2006

View article titled, Retraction

Journal Articles

Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production

Gregory C. Ippolito, Robert L. Schelonka, Michael Zemlin, Ivaylo I. Ivanov, Ryoki Kobayashi, Cosima Zemlin, G. Larry Gartland, Lars Nitschke, Jukka Pelkonen, Kohtaro Fujihashi, Klaus Rajewsky, Harry W. Schroeder, Jr.

J Exp Med (2006) 203 (6): 1567–1578.

https://doi.org/10.1084/jem.20052217

Published: 05 June 2006

View article titled, Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production

Includes: Supplementary data

Journal Articles

Aberrant T cell differentiation in the absence of Dicer

Stefan A. Muljo, K. Mark Ansel, Chryssa Kanellopoulou, David M. Livingston, Anjana Rao, Klaus Rajewsky

J Exp Med (2005) 202 (2): 261–269.

https://doi.org/10.1084/jem.20050678

Published: 11 July 2005

View article titled, Aberrant T cell differentiation in the absence of Dicer

Includes: Supplementary data

Journal Articles

The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival

Malay Mandal, Christine Borowski, Teresa Palomero, Adolfo A. Ferrando, Philipp Oberdoerffer, Fanyong Meng, Antonio Ruiz-Vela, Maria Ciofani, Juan-Carlos Zuniga-Pflucker, Isabella Screpanti, A. Thomas Look, Stanley J. Korsmeyer, Klaus Rajewsky, Harald von Boehmer, Iannis Aifantis

J Exp Med (2005) 201 (4): 603–614.

https://doi.org/10.1084/jem.20041924

Published: 22 February 2005

View article titled, The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival

Journal Articles

Direct in vivo V_H to J_H rearrangement violating the 12/23 rule

Sergei B. Koralov, Tatiana I. Novobrantseva, Konrad Hochedlinger, Rudolf Jaenisch, Klaus Rajewsky

J Exp Med (2005) 201 (3): 341–348.

https://doi.org/10.1084/jem.20041577

Published: 07 February 2005

View article titled, Direct in vivo V<sub>H</sub> to J<sub>H</sub> rearrangement violating the 12/23 rule

Journal Articles

T Cell–specific Inactivation of the Interleukin 10 Gene in Mice Results in Enhanced T Cell Responses but Normal Innate Responses to Lipopolysaccharide or Skin Irritation

Axel Roers, Lisa Siewe, Elke Strittmatter, Martina Deckert, Dirk Schlüter, Werner Stenzel, Achim D. Gruber, Thomas Krieg, Klaus Rajewsky, Werner Müller

J Exp Med (2004) 200 (10): 1289–1297.

https://doi.org/10.1084/jem.20041789

Published: 08 November 2004

View article titled, T Cell–specific Inactivation of the Interleukin 10 Gene in Mice Results in Enhanced T Cell Responses but Normal Innate Responses to Lipopolysaccharide or Skin Irritation

Journal Articles

T Cell–specific Ablation of Fas Leads to Fas Ligand–mediated Lymphocyte Depletion and Inflammatory Pulmonary Fibrosis

Zhenyue Hao, Brigitte Hampel, Hideo Yagita, Klaus Rajewsky

J Exp Med (2004) 199 (10): 1355–1365.

https://doi.org/10.1084/jem.20032196

Published: 17 May 2004

View article titled, T Cell–specific Ablation of Fas Leads to Fas Ligand–mediated Lymphocyte Depletion and Inflammatory Pulmonary Fibrosis

Journal Articles

A B Cell Receptor with Two Igα Cytoplasmic Domains Supports Development of Mature But Anergic B Cells

Amy Reichlin, Anna Gazumyan, Hitoshi Nagaoka, Kathrin H. Kirsch, Manfred Kraus, Klaus Rajewsky, Michel C. Nussenzweig

J Exp Med (2004) 199 (6): 855–865.

https://doi.org/10.1084/jem.20031140

Published: 15 March 2004

View article titled, A B Cell Receptor with Two Igα Cytoplasmic Domains Supports Development of Mature But Anergic B Cells

Journal Articles

Effective Destruction of Fas-deficient Insulin-producing β Cells in Type 1 Diabetes

Irina Apostolou, Zhenyue Hao, Klaus Rajewsky, Harald von Boehmer

J Exp Med (2003) 198 (7): 1103–1106.

https://doi.org/10.1084/jem.20030698

Published: 06 October 2003

View article titled, Effective Destruction of Fas-deficient Insulin-producing β Cells in Type 1 Diabetes

Journal Articles

Expression of a Targeted λ1 Light Chain Gene Is Developmentally Regulated and Independent of Igκ Rearrangements

Philipp Oberdoerffer, Tatiana I. Novobrantseva, Klaus Rajewsky

J Exp Med (2003) 197 (9): 1165–1172.

https://doi.org/10.1084/jem.20030402

Published: 28 April 2003

View article titled, Expression of a Targeted λ1 Light Chain Gene Is Developmentally Regulated and Independent of Igκ Rearrangements

NARROW

miR-23∼27∼24 clusters control effector T cell differentiation and function

Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory

Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination

CIN85 drives B cell responses by linking BCR signals to the canonical NF-κB pathway

PLC-γ2 is essential for formation and maintenance of memory B cells

Polζ ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability

Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching

Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-κB pathway and promotes lymphomagenesis

IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Igα/β

Retraction

Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production

Aberrant T cell differentiation in the absence of Dicer

The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival

Direct in vivo V_H to J_H rearrangement violating the 12/23 rule

T Cell–specific Inactivation of the Interleukin 10 Gene in Mice Results in Enhanced T Cell Responses but Normal Innate Responses to Lipopolysaccharide or Skin Irritation

T Cell–specific Ablation of Fas Leads to Fas Ligand–mediated Lymphocyte Depletion and Inflammatory Pulmonary Fibrosis

A B Cell Receptor with Two Igα Cytoplasmic Domains Supports Development of Mature But Anergic B Cells

Effective Destruction of Fas-deficient Insulin-producing β Cells in Type 1 Diabetes

Expression of a Targeted λ1 Light Chain Gene Is Developmentally Regulated and Independent of Igκ Rearrangements

Email alerts

Email alerts

This Feature Is Available To Subscribers Only