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Mohamed H. Sayegh
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Journal Articles

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy

Xueli Yuan, Jesus Paez-Cortez, Isabela Schmitt-Knosalla, Francesca D'Addio, Bechara Mfarrej, Michela Donnarumma, Antje Habicht, Michael R. Clarkson, John Iacomini, Laurie H. Glimcher, Mohamed H. Sayegh, M. Javeed Ansari
Journal: Journal of Experimental Medicine
J Exp Med (2008) 205 (13): 3133–3144.
https://doi.org/10.1084/jem.20081937
Published: 01 December 2008
View articletitled, A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy
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Journal Articles

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

Sheng Xiao, Nader Najafian, Jay Reddy, Monica Albin, Chen Zhu, Eric Jensen, Jaime Imitola, Thomas Korn, Ana C. Anderson, Zheng Zhang, Cristina Gutierrez, Thomas Moll, Raymond A. Sobel, Dale T. Umetsu, Hideo Yagita, Hisaya Akiba, Terry Strom, Mohamed H. Sayegh, Rosemarie H. DeKruyff, Samia J. Khoury, Vijay K. Kuchroo
Journal: Journal of Experimental Medicine
J Exp Med (2007) 204 (7): 1691–1702.
https://doi.org/10.1084/jem.20062498
Published: 02 July 2007
View articletitled, Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function
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Includes: Supplementary data
Journal Articles

Insulin-induced remission in new-onset NOD mice is maintained by the PD-1–PD-L1 pathway

Brian T. Fife, Indira Guleria, Melanie Gubbels Bupp, Todd N. Eagar, Qizhi Tang, Helene Bour-Jordan, Hideo Yagita, Miyuki Azuma, Mohamed H. Sayegh, Jeffrey A. Bluestone
Journal: Journal of Experimental Medicine
J Exp Med (2006) 203 (12): 2737–2747.
https://doi.org/10.1084/jem.20061577
Published: 20 November 2006
View articletitled, Insulin-induced remission in new-onset NOD mice is maintained by the PD-1–PD-L1 pathway
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Includes: Supplementary data
Journal Articles

Tissue expression of PD-L1 mediates peripheral T cell tolerance

Mary E. Keir, Spencer C. Liang, Indira Guleria, Yvette E. Latchman, Andi Qipo, Lee A. Albacker, Maria Koulmanda, Gordon J. Freeman, Mohamed H. Sayegh, Arlene H. Sharpe
Journal: Journal of Experimental Medicine
J Exp Med (2006) 203 (4): 883–895.
https://doi.org/10.1084/jem.20051776
Published: 10 April 2006
View articletitled, Tissue expression of PD-L1 mediates peripheral T cell tolerance
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Includes: Supplementary data
Journal Articles

A critical role for the programmed death ligand 1 in fetomaternal tolerance

Indira Guleria, Arezou Khosroshahi, Mohammed Javeed Ansari, Antje Habicht, Miyuki Azuma, Hideo Yagita, Randolph J. Noelle, Anthony Coyle, Andrew L. Mellor, Samia J. Khoury, Mohamed H. Sayegh
Journal: Journal of Experimental Medicine
J Exp Med (2005) 202 (2): 231–237.
https://doi.org/10.1084/jem.20050019
Published: 18 July 2005
View articletitled, A critical role for the programmed death ligand 1 in fetomaternal tolerance
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Includes: Supplementary data
Journal Articles

The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice

Mohammed Javeed I. Ansari, Alan D. Salama, Tanuja Chitnis, R. Neal Smith, Hideo Yagita, Hisaya Akiba, Tomohide Yamazaki, Miyuki Azuma, Hideyuki Iwai, Samia J. Khoury, Hugh Auchincloss, Jr., Mohamed H. Sayegh
Journal: Journal of Experimental Medicine
J Exp Med (2003) 198 (1): 63–69.
https://doi.org/10.1084/jem.20022125
Published: 07 July 2003
View articletitled, The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice
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Journal Articles

Critical Role of the Programmed Death-1 (PD-1) Pathway in Regulation of Experimental Autoimmune Encephalomyelitis

Alan D. Salama, Tanuja Chitnis, Jaime Imitola, Mohammed Javeed I. Ansari, Hisaya Akiba, Fumihiko Tushima, Miyuki Azuma, Hideo Yagita, Mohamed H. Sayegh, Samia J. Khoury
Journal: Journal of Experimental Medicine
J Exp Med (2003) 198 (1): 71–78.
https://doi.org/10.1084/jem.20022119
Published: 07 July 2003
View articletitled, Critical Role of the Programmed Death-1 (PD-1) Pathway in Regulation of Experimental Autoimmune Encephalomyelitis
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Journal Articles

CD4+ T Cells Regulate Surgical and Postinfectious Adhesion Formation

Doo Ryeon Chung, Tanuja Chitnis, Ronald J. Panzo, Dennis L. Kasper, Mohamed H. Sayegh, Arthur O. Tzianabos
Journal: Journal of Experimental Medicine
J Exp Med (2002) 195 (11): 1471–1478.
https://doi.org/10.1084/jem.20020028
Published: 03 June 2002
View articletitled, CD4+ T Cells Regulate Surgical and Postinfectious Adhesion Formation
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Journal Articles

Endothelial Cells Modify the Costimulatory Capacity of Transmigrating Leukocytes and Promote Cd28-Mediated Cd4+ T Cell Alloactivation

Mark D. Denton, Christopher S. Geehan, Steve I. Alexander, Mohamed H. Sayegh, David M. Briscoe
Journal: Journal of Experimental Medicine
J Exp Med (1999) 190 (4): 555–566.
https://doi.org/10.1084/jem.190.4.555
Published: 16 August 1999
View articletitled, Endothelial Cells Modify the Costimulatory Capacity of Transmigrating Leukocytes and Promote Cd28-Mediated Cd4+ T Cell Alloactivation
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Journal Articles

Extrathymic T Cell Deletion and Allogeneic Stem Cell Engraftment Induced with Costimulatory Blockade Is Followed by Central T Cell Tolerance

Thomas Wekerle, Mohamed H. Sayegh, Joshua Hill, Yong Zhao, Anil Chandraker, Kirsten G. Swenson, Guiling Zhao, Megan Sykes
Journal: Journal of Experimental Medicine
J Exp Med (1998) 187 (12): 2037–2044.
https://doi.org/10.1084/jem.187.12.2037
Published: 15 June 1998
View articletitled, Extrathymic T Cell Deletion and Allogeneic Stem Cell Engraftment Induced with Costimulatory Blockade Is Followed by Central T Cell Tolerance
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