Page 1 | Search Results | Journal of Experimental Medicine

1-11 of 11

Sort by

Sort Order Select

Journal Articles

PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance

In Special Collection:

JEM Cancer Collection 2021

Catherine L. Tan, Juhi R. Kuchroo, Peter T. Sage, Dan Liang, Loise M. Francisco, Jessica Buck, Youg Raj Thaker, Qianxia Zhang, Shannon L. McArdel, Vikram R. Juneja, Sun Jung Lee, Scott B. Lovitch, Christine Lian, George F. Murphy, Bruce R. Blazar, Dario A.A. Vignali, Gordon J. Freeman, Arlene H. Sharpe

J Exp Med (2020) 218 (1): e20182232.

https://doi.org/10.1084/jem.20182232

Published: 06 October 2020

View articletitled, PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance

Includes: Supplementary data

Journal Articles

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

In Special Collection:

Cancer and Autoimmunity , Lymphocytes and their Roles in Cancer , T Cell Dysfunction, Cancer, and Infection

Vikram R. Juneja, Kathleen A. McGuire, Robert T. Manguso, Martin W. LaFleur, Natalie Collins, W. Nicholas Haining, Gordon J. Freeman, Arlene H. Sharpe

J Exp Med (2017) 214 (4): 895–904.

https://doi.org/10.1084/jem.20160801

Published: 16 March 2017

View articletitled, PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

Journal Articles

Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity

Alison M. Paterson, Scott B. Lovitch, Peter T. Sage, Vikram R. Juneja, Youjin Lee, Justin D. Trombley, Carolina V. Arancibia-Cárcamo, Raymond A. Sobel, Alexander Y. Rudensky, Vijay K. Kuchroo, Gordon J. Freeman, Arlene H. Sharpe

J Exp Med (2015) 212 (10): 1603–1621.

https://doi.org/10.1084/jem.20141030

Published: 14 September 2015

View articletitled, Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity

Journal Articles

Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection

Pablo Penaloza-MacMaster, Alice O. Kamphorst, Andreas Wieland, Koichi Araki, Smita S. Iyer, Erin E. West, Leigh O’Mara, Shu Yang, Bogumila T. Konieczny, Arlene H. Sharpe, Gordon J. Freeman, Alexander Y. Rudensky, Rafi Ahmed

J Exp Med (2014) 211 (9): 1905–1918.

https://doi.org/10.1084/jem.20132577

Published: 11 August 2014

View articletitled, Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection

Journal Articles

RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance

Yanping Xiao, Sanhong Yu, Baogong Zhu, Denis Bedoret, Xia Bu, Loise M. Francisco, Ping Hua, Jonathan S. Duke-Cohan, Dale T. Umetsu, Arlene H. Sharpe, Rosemarie H. DeKruyff, Gordon J. Freeman

J Exp Med (2014) 211 (5): 943–959.

https://doi.org/10.1084/jem.20130790

Published: 21 April 2014

View articletitled, RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance

Journal Articles

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

Loise M. Francisco, Victor H. Salinas, Keturah E. Brown, Vijay K. Vanguri, Gordon J. Freeman, Vijay K. Kuchroo, Arlene H. Sharpe

J Exp Med (2009) 206 (13): 3015–3029.

https://doi.org/10.1084/jem.20090847

Published: 14 December 2009

View articletitled, PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

Includes: Multimedia, Supplementary data

Journal Articles

Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection

Sang-Jun Ha, Scott N. Mueller, E. John Wherry, Daniel L. Barber, Rachael D. Aubert, Arlene H. Sharpe, Gordon J. Freeman, Rafi Ahmed

J Exp Med (2008) 205 (3): 543–555.

https://doi.org/10.1084/jem.20071949

Published: 10 March 2008

View articletitled, Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection

Includes: Supplementary data

Journal Articles

Reinvigorating exhausted HIV-specific T cells via PD-1–PD-1 ligand blockade

Gordon J. Freeman, E. John Wherry, Rafi Ahmed, Arlene H. Sharpe

J Exp Med (2006) 203 (10): 2223–2227.

https://doi.org/10.1084/jem.20061800

Published: 25 September 2006

View articletitled, Reinvigorating exhausted HIV-specific T cells via PD-1–PD-1 ligand blockade

Journal Articles

Tissue expression of PD-L1 mediates peripheral T cell tolerance

Mary E. Keir, Spencer C. Liang, Indira Guleria, Yvette E. Latchman, Andi Qipo, Lee A. Albacker, Maria Koulmanda, Gordon J. Freeman, Mohamed H. Sayegh, Arlene H. Sharpe

J Exp Med (2006) 203 (4): 883–895.

https://doi.org/10.1084/jem.20051776

Published: 10 April 2006

View articletitled, Tissue expression of PD-L1 mediates peripheral T cell tolerance

Includes: Supplementary data

Journal Articles

CD4⁺CD25⁺ T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion

Ann E. Herman, Gordon J. Freeman, Diane Mathis, Christophe Benoist

J Exp Med (2004) 199 (11): 1479–1489.

https://doi.org/10.1084/jem.20040179

Published: 07 June 2004

View articletitled, CD4+CD25+ T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion

Includes: Supplementary data

Journal Articles

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

In Special Collection:

2018 Nobel Prize Collection

Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai, Karen Bourque, Tatyana Chernova, Hiroyuki Nishimura, Lori J. Fitz, Nelly Malenkovich, Taku Okazaki, Michael C. Byrne, Heidi F. Horton, Lynette Fouser, Laura Carter, Vincent Ling, Michael R. Bowman, Beatriz M. Carreno, Mary Collins, Clive R. Wood, Tasuku Honjo

J Exp Med (2000) 192 (7): 1027–1034.

https://doi.org/10.1084/jem.192.7.1027

Published: 02 October 2000

View articletitled, Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Update search

NARROW

Format

Subjects

Journal

Article Type

Filters

Date

PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity

Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection

RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection

Reinvigorating exhausted HIV-specific T cells via PD-1–PD-1 ligand blockade

Tissue expression of PD-L1 mediates peripheral T cell tolerance

CD4⁺CD25⁺ T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Email alerts

Update search

Email alerts

This Feature Is Available To Subscribers Only