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7 June 1999
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Localization of antigen-specific T helper cells (Th) within the draining lymph nodes (DLNs) during an immune response in vivo. Cryosections were prepared from DLNs of B10.BR mice 7 d after immunization with pigeon cytochrome c in adjuvant. Sections were stained for three-color laser-scanning confocal microscopy with FITC–anti-Vα11 (green), allophycocyanin–anti-Vβ3 (red), and Texas red–anti-IgD (cyan). T cells coexpressing Vα11 and Vβ3 appear yellow. Vα11Vβ3-expressing Th accumulate in the germinal centers, identified here as an IgD− region within the IgDbright B cell zone. See related article in this issue by McHeyzer-Williams et al., pp. 1823–1837.
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ISSN 0022-1007
EISSN 1540-9538
In this Issue
Articles
BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth
Pascal Schneider,Fabienne MacKay,Véronique Steiner,Kay Hofmann,Jean-Luc Bodmer,Nils Holler,Christine Ambrose,Pornsri Lawton,Sarah Bixler,Hans Acha-Orbea,Danila Valmori,Pedro Romero,Christiane Werner-Favre,Rudolph H. Zubler,Jeffrey L. Browning,Jürg Tschopp
Thioredoxin, a Redox Enzyme Released in Infection and Inflammation, Is a Unique Chemoattractant for Neutrophils, Monocytes, and T Cells
Riccardo Bertini,O.M. Zack Howard,Hui-Fang Dong,Joost J. Oppenheim,Cinzia Bizzarri,Rita Sergi,Gianfranco Caselli,Sabrina Pagliei,Brie Romines,Jennifer A. Wilshire,Manuela Mengozzi,Hajime Nakamura,Junji Yodoi,Klas Pekkari,Ramanathan Gurunath,Arne Holmgren,Leonore A. Herzenberg,Leonard A. Herzenberg,Pietro Ghezzi