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Volume 184, Issue 6

1 December 1996

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Table of Contents
Editorial Board

ISSN 0022-1007

EISSN 1540-9538

In this Issue

Article
Brief Definitive Report

Article

Counterselection against Dμ Is Mediated through Immunoglobulin (Ig)α-Igβ

Shiaoching Gong,Mercedes Sanchez,Michel C. Nussenzweig

View Articletitled, Counterselection against Dμ Is Mediated through Immunoglobulin (Ig)α-Igβ

Heterogeneity Among Ly-49C Natural Killer (NK) Cells: Characterization of Highly Related Receptors with Differing Functions and Expression Patterns

Jack Brennan,Suzanne Lemieux,J. Douglas Freeman,Dixie L. Mager,Fumio Takei

View Articletitled, Heterogeneity Among Ly-49C Natural Killer (NK) Cells: Characterization of Highly Related Receptors with Differing Functions and Expression Patterns

Lineage Commitment in the Thymus: Only the Most Differentiated (TCR^hibcl-2^hi) Subset of CD4⁺CD8⁺Thymocytes Has Selectively Terminated CD4 or CD8 Synthesis

Jennifer A. Punt,Harumi Suzuki,Larry G. Granger,Susan O. Sharrow,Alfred Singer

View Articletitled, Lineage Commitment in the Thymus: Only the Most Differentiated (TCRhibcl-2hi) Subset of CD4+CD8+Thymocytes Has Selectively Terminated CD4 or CD8 Synthesis

Induction of Murine Acquired Immunodeficiency Syndrome (MAIDS) in Allophenic Mice Generated from Strains Susceptible and Resistant to Disease

Joan M.G. Sechler,Ann Lawler,Janet W. Hartley,Herbert C. Morse, III,Thomas C. McCarty,Ruth Swofford,Amy S. Rosenberg

View Articletitled, Induction of Murine Acquired Immunodeficiency Syndrome (MAIDS) in Allophenic Mice Generated from Strains Susceptible and Resistant to Disease

Apoptosis of Fas^high CD4⁺ Synovial T Cells by Borrelia-reactive Fas-ligand^high γδ T Cells in Lyme Arthritis

Michael S. Vincent,Karen Roessner,David Lynch,David Wilson,Sheldon M. Cooper,Jurg Tschopp,Leonard H. Sigal,Ralph C. Budd

View Articletitled, Apoptosis of Fashigh CD4+ Synovial T Cells by Borrelia-reactive Fas-ligandhigh γδ T Cells in Lyme Arthritis

The Ly-49D Receptor Activates Murine Natural Killer Cells

L.H. Mason,S.K. Anderson,W.M. Yokoyama,H.R.C. Smith,R. Winkler-Pickett,J.R. Ortaldo

View Articletitled, The Ly-49D Receptor Activates Murine Natural Killer Cells

γδ T Cells from Tolerized αβ T Cell Receptor (TCR)–deficient Mice Inhibit Contact Sensitivity-Effector T Cells In Vivo, and Their Interferon-γ Production In Vitro

Marian Szczepanik,Laurel R. Anderson,Hiroko Ushio,Wlodzimierz Ptak,Michael J. Owen,Adrian C. Hayday,Philip W. Askenase

View Articletitled, γδ T Cells from Tolerized αβ T Cell Receptor (TCR)–deficient Mice Inhibit Contact Sensitivity-Effector T Cells In Vivo, and Their Interferon-γ Production In Vitro

Resting Memory CD8⁺ T Cells are Hyperreactive to Antigenic Challenge In Vitro

Maria Pihlgren,Patrice M. Dubois,Martine Tomkowiak,Tove Sjögren,Jacqueline Marvel

View Articletitled, Resting Memory CD8+ T Cells are Hyperreactive to Antigenic Challenge In Vitro

HLA-DM Interactions with Intermediates in HLA-DR Maturation and a Role for HLA-DM in Stabilizing Empty HLA-DR Molecules

Lisa K. Denzin,Craig Hammond,Peter Cresswell

View Articletitled, HLA-DM Interactions with Intermediates in HLA-DR Maturation and a Role for HLA-DM in Stabilizing Empty HLA-DR Molecules

Aerosol Insulin Induces Regulatory CD8 γδ T Cells That Prevent Murine Insulin-dependent Diabetes

Leonard C. Harrison,Majella Dempsey-Collier,David R. Kramer,Kazuma Takahashi

View Articletitled, Aerosol Insulin Induces Regulatory CD8 γδ T Cells That Prevent Murine Insulin-dependent Diabetes

Positive Selection of γδ CTL by TL Antigen Expressed in the Thymus

Kunio Tsujimura,Toshitada Takahashi,Akimichi Morita,Hitomi Hasegawa-Nishiwaki,Shigeru Iwase,Yuichi Obata

View Articletitled, Positive Selection of γδ CTL by TL Antigen Expressed in the Thymus

Dendritic Cell Development in Culture from Thymic Precursor Cells in the Absence of Granulocyte/Macrophage Colony-stimulating Factor

Dolores Saunders,Karen Lucas,Jamila Ismaili,Li Wu,Eugene Maraskovsky,Ashley Dunn,Ken Shortman

View Articletitled, Dendritic Cell Development in Culture from Thymic Precursor Cells in the Absence of Granulocyte/Macrophage Colony-stimulating Factor

The Two Membrane Isoforms of Human IgE Assemble into Functionally Distinct B Cell Antigen Receptors

Facundo D. Batista,Shubha Anand,Gianni Presani,Dimitar G. Efremov,Oscar R. Burrone

View Articletitled, The Two Membrane Isoforms of Human IgE Assemble into Functionally Distinct B Cell Antigen Receptors

Identification of TRP-2 as a Human Tumor Antigen Recognized by Cytotoxic T Lymphocytes

Rong-Fu Wang,Ettore Appella,Yutaka Kawakami,Xiaoqiang Kang,Steven A. Rosenberg

View Articletitled, Identification of TRP-2 as a Human Tumor Antigen Recognized by Cytotoxic T Lymphocytes

Ordering of Human Bone Marrow B Lymphocyte Precursors by Single-Cell Polymerase Chain Reaction Analyses of the Rearrangement Status of the Immunoglobulin H and L Chain Gene Loci

Paolo Ghia,Edwin ten Boekel,Eva Sanz,Antonio de la Hera,Antonius Rolink,Fritz Melchers

View Articletitled, Ordering of Human Bone Marrow B Lymphocyte Precursors by Single-Cell Polymerase Chain Reaction Analyses of the Rearrangement Status of the Immunoglobulin H and L Chain Gene Loci

Antineutrophil Cytoplasmic Autoantibodies Interact with Primary Granule Constituents on the Surface of Apoptotic Neutrophils in the Absence of Neutrophil Priming

Hannah M. Gilligan,Brunel Bredy,Hugh R. Brady,Marie-Josée Hébert,Henry S. Slayter,Yuhui Xu,Joyce Rauch,Michael A. Shia,Jason S. Koh,Jerrold S. Levine

View Articletitled, Antineutrophil Cytoplasmic Autoantibodies Interact with Primary Granule Constituents on the Surface of Apoptotic Neutrophils in the Absence of Neutrophil Priming

Killer Cell Inhibitory Receptor Recognition of Human Leukocyte Antigen (HLA) Class I Blocks Formation of a pp36/PLC-γ Signaling Complex in Human Natural Killer (NK) Cells

Nicholas M. Valiante,Joseph H. Phillips,Lewis L. Lanier,Peter Parham

View Articletitled, Killer Cell Inhibitory Receptor Recognition of Human Leukocyte Antigen (HLA) Class I Blocks Formation of a pp36/PLC-γ Signaling Complex in Human Natural Killer (NK) Cells

Intermediates in the Assembly and Degradation of Class I Major Histocompatibility Complex (MHC) Molecules Probed with Free Heavy Chain–specific Monoclonal Antibodies

Robert P. Machold,Hidde L. Ploegh

View Articletitled, Intermediates in the Assembly and Degradation of Class I Major Histocompatibility Complex (MHC) Molecules Probed with Free Heavy Chain–specific Monoclonal Antibodies

Systemic T Cell–independent Tumor Immunity after Transplantation of Universal Receptor–modified Bone Marrow into SCID Mice

Kristen M. Hege,Keegan S. Cooke,Mitchell H. Finer,Krisztina M. Zsebo,Margo R. Roberts

View Articletitled, Systemic T Cell–independent Tumor Immunity after Transplantation of Universal Receptor–modified Bone Marrow into SCID Mice

Experimental Autoimmune Encephalomyelitis Induction in Genetically B Cell–deficient Mice

Susan D. Wolf,Bonnie N. Dittel,Fridrika Hardardottir,Charles A. Janeway, Jr.

View Articletitled, Experimental Autoimmune Encephalomyelitis Induction in Genetically B Cell–deficient Mice

Antagonist HIV-1 Gag Peptides Induce Structural Changes in HLA B8

Scott W. Reid,Steve McAdam,Kathrine J. Smith,Paul Klenerman,Chris A. O'Callaghan,Karl Harlos,Bent K. Jakobsen,Andrew J. McMichael,John I. Bell,David I. Stuart,E. Yvonne Jones

View Articletitled, Antagonist HIV-1 Gag Peptides Induce Structural Changes in HLA B8

Cross-linking of Fas By Antibodies to a Peculiar Domain of gp120 V3 Loop Can Enhance T Cell Apoptosis in HIV-1–infected Patients

Franco Silvestris,Shigekazu Nagata,Paola Cafforio,Nicola Silvestris,Franco Dammacco

View Articletitled, Cross-linking of Fas By Antibodies to a Peculiar Domain of gp120 V3 Loop Can Enhance T Cell Apoptosis in HIV-1–infected Patients

Preferential Proliferation of Murine Colony-forming Units in Culture in a Chemically Defined Condition with a Macrophage Colony-stimulating Factor–negative Stromal Cell Clone

Nobuyuki Takakura,Hiroaki Kodama,Satomi Nishikawa,Shin-Ichi Nishikawa

View Articletitled, Preferential Proliferation of Murine Colony-forming Units in Culture in a Chemically Defined Condition with a Macrophage Colony-stimulating Factor–negative Stromal Cell Clone

Basement Membrane and Repair of Injury to Peripheral Nerve: Defining a Potential Role for Macrophages, Matrix Metalloproteinases, and Tissue Inhibitor of Metalloproteinases-1

Monique La Fleur,Johnnie L. Underwood,Daniel A. Rappolee,Zena Werb

View Articletitled, Basement Membrane and Repair of Injury to Peripheral Nerve: Defining a Potential Role for Macrophages, Matrix Metalloproteinases, and Tissue Inhibitor of Metalloproteinases-1

Proliferation Kinetics Associated with T Cell Receptor-β Chain Selection of Fetal Murine Thymocytes

Ingrid Falk,Judit Biro,Hubertus Kohler,Klaus Eichmann

View Articletitled, Proliferation Kinetics Associated with T Cell Receptor-β Chain Selection of Fetal Murine Thymocytes

The Route of Antigen Entry Determines the Requirement for L-selectin during Immune Responses

Michelle D. Catalina,Michael C. Carroll,Helen Arizpe,Akira Takashima,Pila Estess,Mark H. Siegelman

View Articletitled, The Route of Antigen Entry Determines the Requirement for L-selectin during Immune Responses

Germinal Center Formation and Local Immunoglobulin E (IgE) Production in the Lung after an Airway Antigenic Challenge

Yolande Chvatchko,Marie H. Kosco-Vilbois,Suzanne Herren,Jean Lefort,Jean-Yves Bonnefoy

View Articletitled, Germinal Center Formation and Local Immunoglobulin E (IgE) Production in the Lung after an Airway Antigenic Challenge

Multiple Sclerosis: Fas Signaling in Oligodendrocyte Cell Death

Sameer D. D'Souza,Bruno Bonetti,Vijayabalan Balasingam,Neil R. Cashman,Philip A. Barker,Anthony B. Troutt,Cedric S. Raine,Jack P. Antel

View Articletitled, Multiple Sclerosis: Fas Signaling in Oligodendrocyte Cell Death

Viral Infection of Transgenic Mice Expressing a Viral Protein in Oligodendrocytes Leads to Chronic Central Nervous System Autoimmune Disease

Claire F. Evans,Marc S. Horwitz,Monte V. Hobbs,Michael B.A. Oldstone

View Articletitled, Viral Infection of Transgenic Mice Expressing a Viral Protein in Oligodendrocytes Leads to Chronic Central Nervous System Autoimmune Disease

Immunoglobulin G–mediated Inflammatory Responses Develop Normally in Complement-deficient Mice

Diana Sylvestre,Raphael Clynes,Minga Ma,Henry Warren,Michael C. Carroll,Jeffrey V. Ravetch

View Articletitled, Immunoglobulin G–mediated Inflammatory Responses Develop Normally in Complement-deficient Mice

Brief Definitive Report

The Thymus Contains a High Frequency of Cells that Prevent Autoimmune Diabetes on Transfer into Prediabetic Recipients

Abdelhadi Saoudi,Benedict Seddon,Debbie Fowell,Don Mason

View Articletitled, The Thymus Contains a High Frequency of Cells that Prevent Autoimmune Diabetes on Transfer into Prediabetic Recipients

Proteolytic Activation of Protein Kinase C δ by an ICE/CED 3-like Protease Induces Characteristics of Apoptosis

Tariq Ghayur,Margaret Hugunin,Robert V. Talanian,Sheldon Ratnofsky,Christopher Quinlan,Yutaka Emoto,Pramod Pandey,Rakesh Datta,Yinyin Huang,Surender Kharbanda,Hamish Allen,Robert Kamen,Winnie Wong,Donald Kufe

View Articletitled, Proteolytic Activation of Protein Kinase C δ by an ICE/CED 3-like Protease Induces Characteristics of Apoptosis

The Involvement of Interleukin (IL)-15 in Regulating the Differentiation of Granulated Metrial Gland Cells in Mouse Pregnant Uterus

Weiguo Ye,Li-Mou Zheng,John Young,Chau-Ching Liu

View Articletitled, The Involvement of Interleukin (IL)-15 in Regulating the Differentiation of Granulated Metrial Gland Cells in Mouse Pregnant Uterus

Ceramide Inhibits Antigen Uptake and Presentation by Dendritic Cells

Federica Sallusto,Chiara Nicolò,Ruggero De Maria,Silvia Corinti,Roberto Testi

View Articletitled, Ceramide Inhibits Antigen Uptake and Presentation by Dendritic Cells

A Role for Endogenous Transforming Growth Factor β1 in Langerhans Cell Biology: The Skin of Transforming Growth Factor β1 Null Mice Is Devoid of Epidermal Langerhans Cells

Teresa A. Borkowski,John J. Letterio,Andrew G. Farr,Mark C. Udey

View Articletitled, A Role for Endogenous Transforming Growth Factor β1 in Langerhans Cell Biology: The Skin of Transforming Growth Factor β1 Null Mice Is Devoid of Epidermal Langerhans Cells

The V–J Recombination of T Cell Receptor-γ Genes Is Blocked in Interleukin-7 Receptor–deficient Mice

Kazushige Maki,Shinji Sunaga,Koichi Ikuta

View Articletitled, The V–J Recombination of T Cell Receptor-γ Genes Is Blocked in Interleukin-7 Receptor–deficient Mice

Dendritic Cells Are Recruited into the Airway Epithelium during the Inflammatory Response to a Broad Spectrum of Stimuli

Andrew S. McWilliam,Sylvia Napoli,Amanda M. Marsh,Francis L. Pemper,Delia J. Nelson,Carolyn L. Pimm,Philip A. Stumbles,Timothy N.C. Wells,Patrick G. Holt

View Articletitled, Dendritic Cells Are Recruited into the Airway Epithelium during the Inflammatory Response to a Broad Spectrum of Stimuli

Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors

Angela Granelli-Piperno,Bernhard Moser,Melissa Pope,Dongling Chen,Yang Wei,Frank Isdell,Una O'Doherty,William Paxton,Richard Koup,Svetlana Mojsov,Nina Bhardwaj,Ian Clark-Lewis,Marco Baggiolini,Ralph M. Steinman

View Articletitled, Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors

CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding

Valery Renard,Pedro Romero,Eric Vivier,Bernard Malissen,Immanuel F. Luescher

View Articletitled, CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding

Different Interleukin-1β Converting Enzyme (ICE) Family Protease Requirements for the Apoptotic Death of T Lymphocytes Triggered by Diverse Stimuli

Apurva Sarin,Ming-Lei Wu,Pierre A. Henkart

View Articletitled, Different Interleukin-1β Converting Enzyme (ICE) Family Protease Requirements for the Apoptotic Death of T Lymphocytes Triggered by Diverse Stimuli

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