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Andrea Musacchio
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Journal Articles

Interactions with multiple inner kinetochore proteins determine mitotic localization of FACT

Julia Schweighofer, Bhagyashree Mulay, Ingrid Hoffmann, Doro Vogt, Marion E. Pesenti, Andrea Musacchio
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (5): e202412042.
https://doi.org/10.1083/jcb.202412042
Published: 17 March 2025
View article titled, Interactions with multiple inner kinetochore proteins determine mitotic localization of FACT
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Includes: Supplementary data
Journal Articles

Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin

Ennio A. d’Amico, Misbha Ud Din Ahmad, Verena Cmentowski, Mathias Girbig, Franziska Müller, Sabine Wohlgemuth, Andreas Brockmeyer, Stefano Maffini, Petra Janning, Ingrid R. Vetter, Andrew P. Carter, Anastassis Perrakis, Andrea Musacchio
Journal: Journal of Cell Biology
J Cell Biol (2022) 221 (11): e202206131.
https://doi.org/10.1083/jcb.202206131
Published: 15 September 2022
View article titled, Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin
Open the PDF for Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin in another window
Includes: Supplementary data
Journal Articles

JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport

In Special Collection:
Cellular Neurobiology 2023
Ricardo Celestino, José B. Gama, Artur F. Castro-Rodrigues, Daniel J. Barbosa, Helder Rocha, Ennio A. d’Amico, Andrea Musacchio, Ana Xavier Carvalho, João H. Morais-Cabral, Reto Gassmann
Journal: Journal of Cell Biology
J Cell Biol (2022) 221 (8): e202110057.
https://doi.org/10.1083/jcb.202110057
Published: 13 July 2022
View article titled, JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport
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Includes: Supplementary data
Journal Articles

Structure of the RZZ complex and molecular basis of its interaction with Spindly

In Special Collection:
Cell Division 2018 , Cytoskeletal Dynamics 2018 , Immune Cell Biology 2019
Shyamal Mosalaganti, Jenny Keller, Anika Altenfeld, Michael Winzker, Pascaline Rombaut, Michael Saur, Arsen Petrovic, Annemarie Wehenkel, Sabine Wohlgemuth, Franziska Müller, Stefano Maffini, Tanja Bange, Franz Herzog, Herbert Waldmann, Stefan Raunser, Andrea Musacchio
Journal: Journal of Cell Biology
J Cell Biol (2017) 216 (4): 961–981.
https://doi.org/10.1083/jcb.201611060
Published: 20 March 2017
View article titled, Structure of the RZZ complex and molecular basis of its interaction with Spindly
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Includes: Supplementary data
Journal Articles

CENP-C is a blueprint for constitutive centromere–associated network assembly within human kinetochores

Kerstin Klare, John R. Weir, Federica Basilico, Tomasz Zimniak, Lucia Massimiliano, Nina Ludwigs, Franz Herzog, Andrea Musacchio
Journal: Journal of Cell Biology
J Cell Biol (2015) 210 (1): 11–22.
https://doi.org/10.1083/jcb.201412028
Published: 29 June 2015
View article titled, CENP-C is a blueprint for constitutive centromere–associated network assembly within human kinetochores
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Includes: Supplementary data
Journal Articles

Panta rhei: The APC/C at steady state

Ivana Primorac, Andrea Musacchio
Journal: Journal of Cell Biology
J Cell Biol (2013) 201 (2): 177–189.
https://doi.org/10.1083/jcb.201301130
Published: 15 April 2013
View article titled, Panta rhei: The APC/C at steady state
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Journal Articles

A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B

Anna De Antoni, Stefano Maffini, Stefan Knapp, Andrea Musacchio, Stefano Santaguida
Journal: Journal of Cell Biology
J Cell Biol (2012) 199 (2): 269–284.
https://doi.org/10.1083/jcb.201205119
Published: 15 October 2012
View article titled, A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B
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Includes: Supplementary data
Journal Articles

Structural analysis reveals features of the spindle checkpoint kinase Bub1–kinetochore subunit Knl1 interaction

Veronica Krenn, Annemarie Wehenkel, Xiaozheng Li, Stefano Santaguida, Andrea Musacchio
Journal: Journal of Cell Biology
J Cell Biol (2012) 196 (4): 451–467.
https://doi.org/10.1083/jcb.201110013
Published: 13 February 2012
View article titled, Structural analysis reveals features of the spindle checkpoint kinase Bub1–kinetochore subunit Knl1 interaction
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Includes: Supplementary data
Journal Articles

The MIS12 complex is a protein interaction hub for outer kinetochore assembly

Arsen Petrovic, Sebastiano Pasqualato, Prakash Dube, Veronica Krenn, Stefano Santaguida, Davide Cittaro, Silvia Monzani, Lucia Massimiliano, Jenny Keller, Aldo Tarricone, Alessio Maiolica, Holger Stark, Andrea Musacchio
Journal: Journal of Cell Biology
J Cell Biol (2010) 190 (5): 835–852.
https://doi.org/10.1083/jcb.201002070
Published: 06 September 2010
View article titled, The MIS12 complex is a protein interaction hub for outer kinetochore assembly
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Includes: Supplementary data
Journal Articles

Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1–C-Mad2 core complex

Laura Hewitt, Anthony Tighe, Stefano Santaguida, Anne M. White, Clifford D. Jones, Andrea Musacchio, Stephen Green, Stephen S. Taylor
Journal: Journal of Cell Biology
J Cell Biol (2010) 190 (1): 25–34.
https://doi.org/10.1083/jcb.201002133
Published: 12 July 2010
View article titled, Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1–C-Mad2 core complex
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Includes: Supplementary data
Journal Articles

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

Stefano Santaguida, Anthony Tighe, Anna Morena D'Alise, Stephen S. Taylor, Andrea Musacchio
Journal: Journal of Cell Biology
J Cell Biol (2010) 190 (1): 73–87.
https://doi.org/10.1083/jcb.201001036
Published: 12 July 2010
View article titled, Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
Open the PDF for Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine in another window
Includes: Supplementary data
Journal Articles

Accumulation of Mad2–Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae

Luigi Nezi, Giulia Rancati, Anna De Antoni, Sebastiano Pasqualato, Simonetta Piatti, Andrea Musacchio
Journal: Journal of Cell Biology
J Cell Biol (2006) 174 (1): 39–51.
https://doi.org/10.1083/jcb.200602109
Published: 03 July 2006
View article titled, Accumulation of Mad2–Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in <em>Saccharomyces cerevisiae </em>
Open the PDF for Accumulation of Mad2–Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in <em>Saccharomyces cerevisiae </em> in another window
Includes: Supplementary data