Issues

In This Issue

Prions show their good side

Mitch Leslie
View Articletitled, Prions show their good side

When cells make a meal of themselves

Mitch Leslie
View Articletitled, When cells make a meal of themselves

Rac1 takes a trip

Mitch Leslie
View Articletitled, Rac1 takes a trip

Tag team at the telomeres

Mitch Leslie
View Articletitled, Tag team at the telomeres

CENP-E goes fishing for microtubules

Mitch Leslie
View Articletitled, CENP-E goes fishing for microtubules

Research Roundup

Shuffling of neuronal receptors

Nicole LeBrasseur
View Articletitled, Shuffling of neuronal receptors

Hungry cells eat ribosomes

Nicole LeBrasseur
View Articletitled, Hungry cells eat ribosomes

Pseudokinase is active after all

Nicole LeBrasseur
View Articletitled, Pseudokinase is active after all

Channel changes customers

Nicole LeBrasseur
View Articletitled, Channel changes customers

mTOR sends T cells on their way

Nicole LeBrasseur
View Articletitled, mTOR sends T cells on their way

People & Ideas

Lloyd Trotman: Of mice and men, cancer, and PTEN

Caitlin Sedwick
View Articletitled, Lloyd Trotman: Of mice and men, cancer, and PTEN

Editorial

You wrote it; you own it!

Emma Hill,Mike Rossner
View Articletitled, You wrote it; you own it!

Spotlight

All quiet on the neuronal front: NMDA receptor inhibition by prion protein

Andrew D. Steele
View Articletitled, All quiet on the neuronal front: NMDA receptor inhibition by prion protein

Report

CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether

Yumi Kim,John E. Heuser,Clare M. Waterman,Don W. Cleveland
View Articletitled, CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether

Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle

Gohta Goshima,Mirjam Mayer,Nan Zhang,Nico Stuurman,Ronald D. Vale
View Articletitled, Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle

Polo-like kinase is required for Golgi and bilobe biogenesis in Trypanosoma brucei

Christopher L. de Graffenried,Helen H. Ho,Graham Warren
View Articletitled, Polo-like kinase is required for Golgi and bilobe biogenesis in <em>Trypanosoma brucei </em>

Kindlin-2 (Mig-2): a co-activator of β3 integrins

Yan-Qing Ma,Jun Qin,Chuanyue Wu,Edward F. Plow
View Articletitled, Kindlin-2 (Mig-2): a co-activator of β<sub>3</sub> integrins

Article

Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes

Sahn-ho Kim,Albert R. Davalos,Seok-Jin Heo,Francis Rodier,Ying Zou,Christian Beausejour,Patrick Kaminker,Steven M. Yannone,Judith Campisi
View Articletitled, Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes

Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation

Yueting Shang,Tadashi Yoshida,Brad A. Amendt,James F. Martin,Gary K. Owens
View Articletitled, Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation

Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication

Jun Wu,Hyekyung P. Cho,David B. Rhee,Dabney K. Johnson,John Dunlap,Yie Liu,Yisong Wang
View Articletitled, Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication

Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

David Michaelson,Wasif Abidi,Daniele Guardavaccaro,Mo Zhou,Ian Ahearn,Michele Pagano,Mark R. Philips
View Articletitled, Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

In Special Collection: JCB65: Autophagy
Taichi Hara,Akito Takamura,Chieko Kishi,Shun-ichiro Iemura,Tohru Natsume,Jun-Lin Guan,Noboru Mizushima
View Articletitled, FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

Presynaptic Type III Neuregulin1-ErbB signaling targets α7 nicotinic acetylcholine receptors to axons

Melissa L. Hancock,Sarah E. Canetta,Lorna W. Role,David A. Talmage
View Articletitled, Presynaptic Type III Neuregulin1-ErbB signaling targets α7 nicotinic acetylcholine receptors to axons

The formin mDia2 stabilizes microtubules independently of its actin nucleation activity

Francesca Bartolini,James B. Moseley,Jan Schmoranzer,Lynne Cassimeris,Bruce L. Goode,Gregg G. Gundersen
View Articletitled, The formin mDia2 stabilizes microtubules independently of its actin nucleation activity

Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K–Akt signaling

Naoto Kakinuma,Badal Chandra Roy,Yun Zhu,Yong Wang,Ryoiti Kiyama
View Articletitled, Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K–Akt signaling

Prion protein attenuates excitotoxicity by inhibiting NMDA receptors

Houman Khosravani,Yunfeng Zhang,Shigeki Tsutsui,Shahid Hameed,Christophe Altier,Jawed Hamid,Lina Chen,Michelle Villemaire,Zenobia Ali,Frank R. Jirik,Gerald W. Zamponi
View Articletitled, Prion protein attenuates excitotoxicity by inhibiting NMDA receptors