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Issues

Generally Physiological

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Tasting the bitter and the sweet, honeybee memories, and visualizing calcium throughout entire astrocytes

Elizabeth M. Adler
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Commentary

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A mechanism for different receptors coupled to the same G protein to generate different responses mediated by different second messengers

Don-On Daniel Mak
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Skeletal muscle fibers: Inactivated or depleted after long depolarizations?

Werner Melzer
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Article

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Quantitative properties and receptor reserve of the IP3 and calcium branch of Gq-coupled receptor signaling

Eamonn J. Dickson,Björn H. Falkenburger,Bertil Hille
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Quantitative properties and receptor reserve of the DAG and PKC branch of Gq-coupled receptor signaling

Björn H. Falkenburger,Eamonn J. Dickson,Bertil Hille
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Major contribution of sarcoplasmic reticulum Ca2+ depletion during long-lasting activation of skeletal muscle

Gaëlle Robin,Bruno Allard
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Comparison of myoplasmic calcium movements during excitation–contraction coupling in frog twitch and mouse fast-twitch muscle fibers

Stephen Hollingworth,Stephen M. Baylor
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TMEM16F (Anoctamin 6), an anion channel of delayed Ca2+ activation

Søren Grubb,Kristian A. Poulsen,Christian Ammitzbøll Juul,Tania Kyed,Thomas K. Klausen,Erik Hviid Larsen,Else K. Hoffmann
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S1–S3 counter charges in the voltage sensor module of a mammalian sodium channel regulate fast inactivation

James R. Groome,Vern Winston
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Atomic-level simulation of current–voltage relationships in single-file ion channels

Morten Ø. Jensen,Vishwanath Jogini,Michael P. Eastwood,David E. Shaw
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Methods and Approaches

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Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses

Eiji Shigetomi,Eric A. Bushong,Martin D. Haustein,Xiaoping Tong,Olan Jackson-Weaver,Sebastian Kracun,Ji Xu,Michael V. Sofroniew,Mark H. Ellisman,Baljit S. Khakh
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Communication

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The food dye FD&C Blue No. 1 is a selective inhibitor of the ATP release channel Panx1

Junjie Wang,David George Jackson,Gerhard Dahl
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