Skip to Main Content

Advertisement

Close

About the Press
For Librarians
Rights & Permissions
Books Open External Link
JCB Journal of Cell Biology
JEM Journal of Experimental Medicine
JGP Journal of General Physiology
JHI Journal of Human Immunity
LSA Open External Link Life Science Alliance

JCB

JEM

JGP

JHI

LSA

header search

Search input auto suggest

filter your search

Advanced Search

Menu

- Special Collections
- Special Issues
Email Alerts

Issues

Select Decade

Select Year

Issue

Volume 141, Issue 4

1 April 2013

Journal of General Physiology Cover Image for Volume 141, Issue 4

Previous Issue
Next Issue

Cover Image

Cover Image

Cover picture: Transport phenotypes of EcClC and its point mutants as observed in solid-supported membrane electrophysiology experiments. WT, the stoichiometric 2Cl⁻/1H⁺ exchange of EcClC; WT/DIDS, the irreversible inhibition by covalent binding of DIDS from the intracellular side; E148A, uncoupled Cl⁻ permeation in a mutant of the external H⁺ acceptor; E203Q, the pH dependence of uncoupled Cl⁻ permeation in a mutant of the internal H⁺ acceptor (see Methods and Approaches by Garcia-Celma et al., 479–491).
Table of Contents
Editorial Board

ISSN 0022-1295

EISSN 1540-7748

In this Issue

Editorial
Generally Physiological
Commentary
Article
Methods and Approaches
Communication
Letter to the Editor

Editorial

New mandates? No problem for The Rockefeller University Press

Mike Rossner

View Articletitled, New mandates? No problem for The Rockefeller University Press

Generally Physiological

Looking to the past and to the future

Elizabeth M. Adler

View Articletitled, Looking to the past and to the future

Commentary

The where and how of PIP regulation of cone photoreceptor CNG channels

Lei Zhou,Diomedes E. Logothetis

View Articletitled, The where and how of PIP regulation of cone photoreceptor CNG channels

The electric heart of hERG

León D. Islas

View Articletitled, The electric heart of hERG

Article

Two structural components in CNGA3 support regulation of cone CNG channels by phosphoinositides

Gucan Dai,Changhong Peng,Chunming Liu,Michael D. Varnum

View Articletitled, Two structural components in CNGA3 support regulation of cone CNG channels by phosphoinositides

Components of gating charge movement and S4 voltage-sensor exposure during activation of hERG channels

Zhuren Wang,Ying Dou,Samuel J. Goodchild,Zeineb Es-Salah-Lamoureux,David Fedida

View Articletitled, Components of gating charge movement and S4 voltage-sensor exposure during activation of hERG channels

Construction and validation of a homology model of the human voltage-gated proton channel hH_V1

Kethika Kulleperuma,Susan M.E. Smith,Deri Morgan,Boris Musset,John Holyoake,Nilmadhab Chakrabarti,Vladimir V. Cherny,Thomas E. DeCoursey,Régis Pomès

View Articletitled, Construction and validation of a homology model of the human voltage-gated proton channel hH<sub>V</sub>1

Loop C and the mechanism of acetylcholine receptor–channel gating

Prasad Purohit,Anthony Auerbach

View Articletitled, Loop C and the mechanism of acetylcholine receptor–channel gating

Methods and Approaches

Functional characterization of a ClC transporter by solid-supported membrane electrophysiology

Juan Garcia-Celma,Adrian Szydelko,Raimund Dutzler

View Articletitled, Functional characterization of a ClC transporter by solid-supported membrane electrophysiology

Communication

Lack of negative slope in I-V plots for BK channels at positive potentials in the absence of intracellular blockers

Yanyan Geng,Xiaoyu Wang,Karl L. Magleby

View Articletitled, Lack of negative slope in I-V plots for BK channels at positive potentials in the absence of intracellular blockers

Ca²⁺ block and flickering both contribute to the negative slope of the IV curve in BK channels

Indra Schroeder,Gerhard Thiel,Ulf-Peter Hansen

View Articletitled, Ca<sup>2+</sup> block and flickering both contribute to the negative slope of the IV curve in BK channels

Letter to the Editor

Using hierarchical thermodynamic linkage analysis to study ion channel gating

Tzilhav Shem-Ad,Ofer Yifrach

View Articletitled, Using hierarchical thermodynamic linkage analysis to study ion channel gating

Email alerts

Complete Issue Alert

Daily Publication Alert

Close alert sign-up modal

Most Read

The physical basis of osmosis

Mechanisms underlying the distinct K⁺ dependencies of periodic paralysis

AMPK-mediated HCN4 channel phosphorylation contributes to age-related intrinsic bradycardia

Artificial intelligence approaches to the volumetric quantification of glycogen granules in EM images of human tissue

Contractile Function

Marfan syndrome cardiomyocytes show excess of titin isoform N2BA and extended sarcomeric M-band

Advertisement

Newest Articles
Current Issue
Archive
Alerts

Submit a Manuscript
Instructions for Authors
For Librarians
About JGP

Editors & Staff
Policies & Permissions
Accessibility Statement
Cookie Policy

Terms & Conditions
Advertise
Contact Us
Newsroom

Privacy Policy
RSS Feeds

Facebook
X/Twitter
Instagram
YouTube
LinkedIn
WeChat
Bluesky

© 2026 Rockefeller University Press

Cookie Settings

Online ISSN 1540-7748
Print ISSN 0022-1295

This Feature Is Available To Subscribers Only

Sign In or Create an Account

Close subscription notice

Close access options

Sharing Unavailable

Sharing content requires targeting cookies to be enabled. Please update your cookie preferences to use this feature.