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Volume 136, Issue 3

1 September 2010

Journal of General Physiology Cover Image for Volume 136, Issue 3

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Cover Image

Cover Image

Cover picture: Airway surface liquid (ASL) depth measured by surface laser reflectance microscopy (SLRM). (Left) SLRM images of airway surface liquid at three locations in primary human bronchial epithelial cell culture. Dashed white line indicates ASL surface. (Middle) Intensity versus distance profiles. (Right) Confocal fluorescence image showing red-stained airway surface liquid and green-stained epithelium. Fluorescence z-profile and depth number histogram shown below images. Bars, 10 µm (see tutorial research article by Thiagarajah et al., 353–362).
Table of Contents
Editorial Board

ISSN 0022-1295

EISSN 1540-7748

In this Issue

Commentary
Article
Tutorial
Letter to the Editor

Commentary

How is the heart rate regulated in the sinoatrial node? Another piece to the puzzle

H. Peter Larsson

View Articletitled, How is the heart rate regulated in the sinoatrial node? Another piece to the puzzle

Post-tetanic potentiation involves the presynaptic binding of calcium to calmodulin

Veeramuthu Balakrishnan,Geetha Srinivasan,Henrique von Gersdorff

View Articletitled, Post-tetanic potentiation involves the presynaptic binding of calcium to calmodulin

Article

Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node

Zhandi Liao,Dean Lockhead,Eric D. Larson,Catherine Proenza

View Articletitled, Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node

Post-tetanic increase in the fast-releasing synaptic vesicle pool at the expense of the slowly releasing pool

Jae Sung Lee,Won-Kyung Ho,Suk-Ho Lee

View Articletitled, Post-tetanic increase in the fast-releasing synaptic vesicle pool at the expense of the slowly releasing pool

Arrangement of Kv1 α subunits dictates sensitivity to tetraethylammonium

Ahmed Al-Sabi,Oleg Shamotienko,Sorcha Ni Dhochartaigh,Nagesh Muniyappa,Marie Le Berre,Hamdy Shaban,Jiafu Wang,Jon T. Sack,J. Oliver Dolly

View Articletitled, Arrangement of Kv1 α subunits dictates sensitivity to tetraethylammonium

Type 1 IP₃ receptors activate BK_Ca channels via local molecular coupling in arterial smooth muscle cells

Guiling Zhao,Zachary P. Neeb,M. Dennis Leo,Judith Pachuau,Adebowale Adebiyi,Kunfu Ouyang,Ju Chen,Jonathan H. Jaggar

View Articletitled, Type 1 IP<sub>3</sub> receptors activate BK<sub>Ca</sub> channels via local molecular coupling in arterial smooth muscle cells

Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation

Yonghong Bai,Min Li,Tzyh-Chang Hwang

View Articletitled, Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation

A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels

Antonella Gradogna,Elena Babini,Alessandra Picollo,Michael Pusch

View Articletitled, A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels

Paradoxical buffering of calcium by calsequestrin demonstrated for the calcium store of skeletal muscle

Leandro Royer,Monika Sztretye,Carlo Manno,Sandrine Pouvreau,Jingsong Zhou,Bjorn C. Knollmann,Feliciano Protasi,Paul D. Allen,Eduardo Ríos

View Articletitled, Paradoxical buffering of calcium by calsequestrin demonstrated for the calcium store of skeletal muscle

Fatty acid modulation and polyamine block of GluK2 kainate receptors analyzed by scanning mutagenesis

Timothy J. Wilding,Kevin Chen,James E. Huettner

View Articletitled, Fatty acid modulation and polyamine block of GluK2 kainate receptors analyzed by scanning mutagenesis

Tutorial

Airway surface liquid depth imaged by surface laser reflectance microscopy

Jay R. Thiagarajah,Yuanlin Song,Nico Derichs,A.S. Verkman

View Articletitled, Airway surface liquid depth imaged by surface laser reflectance microscopy

Letter to the Editor

A mesoscopic approach to understanding the mechanisms underlying the ion permeation on the discrete-state diagram

Shigetoshi Oiki,Masayuki Iwamoto,Takashi Sumikama

View Articletitled, A mesoscopic approach to understanding the mechanisms underlying the ion permeation on the discrete-state diagram

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Drugs exhibit diverse binding modes and access routes in the Na_v1.5 cardiac sodium channel pore

TREK-1 channels regulate pressure sensitivity and calcium signaling in trabecular meshwork cells

ATP synthase: Evolution, energetics, and membrane interactions

Voltage-Gated Na Channels

Sensory neuron sodium channels as pain targets; from cocaine to Journavx (VX-548, suzetrigine)

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