Page 1 | Search Results | Journal of Experimental Medicine

1-20 of 496

Sort by

Sort Order Select

Journal Articles

Single-cell and spatial profiling highlights TB-induced myofibroblasts as drivers of lung pathology

J Exp Med (2026) 223 (3): e20251067.

https://doi.org/10.1084/jem.20251067

Published: 05 January 2026

View article titled, Single-cell and spatial profiling highlights TB-induced myofibroblasts as drivers of lung pathology

Includes: Supplementary data

Journal Articles

Transcription of HIV-1 is heterogenous among authentic latent CD4⁺ T cell clones

Cintia Bittar, Ana Rafaela Teixeira, Thiago Y. Oliveira, Gabriela S. Silva Santos, Klara Lenart, Marcilio Jorge Fumagalli, Georg H.J. Weymar, Anna Kaczynska, Noemi L. Linden, Isabella A.T.M. Ferreira, Marina Caskey, R. Brad Jones, Mila Jankovic, Michel C. Nussenzweig

J Exp Med (2025) 223 (3): e20251584.

https://doi.org/10.1084/jem.20251584

Published: 26 December 2025

View article titled, Transcription of HIV-1 is heterogenous among authentic latent CD4+ T cell clones

Includes: Supplementary data

Journal Articles

ERAdP facilitates biogenesis of dense core vesicles in Paneth cells to enhance intestinal defense

Cunzhen Li, Zhen Xiong, Deyuan Kong, Yuwei Xu, Runyuan Wu, Peikang Zhang, Ziqi Xiao, Hui Guo, Ying Du, JinSong Li, Yun Chen, Qiang Zhan, Zusen Fan

J Exp Med (2025) 223 (2): e20251051.

https://doi.org/10.1084/jem.20251051

Published: 26 December 2025

View article titled, ERAdP facilitates biogenesis of dense core vesicles in Paneth cells to enhance intestinal defense

Includes: Supplementary data

Journal Articles

Antibiotic use in early life impairs MAIT cell–mediated immunity in adulthood

Gabrielle R. LeBlanc, Adam L. Sobel, Jonathan Melamed, Dominic Haas, Eduard Ansaldo, Aiko M. Cirone, Elizabeth Murguia, Michael G. Constantinides

J Exp Med (2025) 223 (3): e20241287.

https://doi.org/10.1084/jem.20241287

Published: 16 December 2025

View article titled, Antibiotic use in early life impairs MAIT cell–mediated immunity in adulthood

Journal Articles

Does fever drive the evolution of antiviral genes?

Ryan A. Langlois

J Exp Med (2025) 223 (1): e20251747.

https://doi.org/10.1084/jem.20251747

Published: 11 December 2025

View article titled, Does fever drive the evolution of antiviral genes?

Journal Articles

Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis

J Exp Med (2025) 223 (3): e20251760.

https://doi.org/10.1084/jem.20251760

Published: 05 December 2025

View article titled, Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis

Journal Articles

Dynamics of natural and pharmacologic control of an SIV variant with an envelope trafficking defect

J Exp Med (2025) 223 (2): e20251172.

https://doi.org/10.1084/jem.20251172

Published: 05 December 2025

View article titled, Dynamics of natural and pharmacologic control of an SIV variant with an envelope trafficking defect

Includes: Supplementary data

Journal Articles

Autoantibodies neutralizing type I IFNs in a fatal case of H5N1 avian influenza

Qian Zhang, Taylor S. Conrad, Marcela Moncada-Velez, Kaijun Jiang, Anastasija Cupic, Jonathan Eaton, Kimberley Hutchinson, Adrian Gervais, Ruyue Chen, Anne Puel, Paul Bastard, Aurelie Cobat, Theresa Sokol, Ryan A. Langlois, Lisa Miorin, Adolfo García-Sastre, John A. Vanchiere, Jean-Laurent Casanova

J Exp Med (2025) 223 (3): e20251962.

https://doi.org/10.1084/jem.20251962

Published: 05 December 2025

View article titled, Autoantibodies neutralizing type I IFNs in a fatal case of H5N1 avian influenza

Journal Articles

pDCs amplify tissue-resident memory CD8⁺ T cell responses during viral reinfection

Elena Hernández-García, Miguel Galán, Sofía C. Khouili, Elena Moya-Ruiz, Ana Redondo-Urzainqui, Francisco J. Cueto, Saraí Martínez-Cano, Manuel Rodrigo-Tapias, Elena Tomasello, Santos Mañes, Marc Dalod, David Sancho, Salvador Iborra

J Exp Med (2025) 223 (2): e20250099.

https://doi.org/10.1084/jem.20250099

Published: 25 November 2025

View article titled, pDCs amplify tissue-resident memory CD8+ T cell responses during viral reinfection

Journal Articles

SLC7A8 is essential for metabolic fitness and function of Th2 cells

Santosh K. Panda, Do-Hyun Kim, Pritesh Desai, Shitong Wu, Patrick Fernandes Rodrigues, Raki Sudan, Yizhou Liu, Haerin Jung, Intelly Lee, Susan Gilfillan, Marina Cella, Steven J. Van Dyken, Marco Colonna

J Exp Med (2025) 223 (2): e20250439.

https://doi.org/10.1084/jem.20250439

Published: 21 November 2025

View article titled, SLC7A8 is essential for metabolic fitness and function of Th2 cells

Journal Articles

Heterologous mucosal vaccine boosting enhances mucosal and systemic immunity by distinct mechanisms

Cameron Bissett, Lyn Yong, Alexandra J. Spencer, Fionn Nok Lam Ma, Ethan A. Courchesne, Reshma Koolaparambil Mukesh, Marta Ulaszewska, Alexander Sampson, Marie Lucienne, Reshma Kailath, Susan Morris, Claire Powers, Sandra Belij-Rammerstorfer, Vincent J. Munster, Neeltje van Doremalen, Nicholas M. Provine, Teresa Lambe

J Exp Med (2025) 223 (1): e20241529.

https://doi.org/10.1084/jem.20241529

Published: 30 October 2025

View article titled, Heterologous mucosal vaccine boosting enhances mucosal and systemic immunity by distinct mechanisms

Includes: Supplementary data

Journal Articles

Genetically heterozygous - transcriptionally homozygous IRF7 deficiency underlies herpesvirus CNS infections in humans

J Exp Med (2025) 223 (1): e20250492.

https://doi.org/10.1084/jem.20250492

Published: 29 October 2025

View article titled, Genetically heterozygous - transcriptionally homozygous IRF7 deficiency underlies herpesvirus CNS infections in humans

Includes: Supplementary data

Journal Articles

Lung tissue–resident memory T cells optimize protection by IL-10 regulation of innate immunity

Alexander Y. Yang, Julia Davis-Porada, Daniel H. Paik, Alex B. George, Brea H. Brown, Paige L. Ruschke, Peter A. Sims, Ziv Frankenstein, Anjali Saqi, Donna L. Farber

J Exp Med (2025) 223 (1): e20242307.

https://doi.org/10.1084/jem.20242307

Published: 13 October 2025

View article titled, Lung tissue–resident memory T cells optimize protection by IL-10 regulation of innate immunity

Includes: Supplementary data

Journal Articles

Role for NF-κB in herpes encephalitis pathology in mice genocopying an inborn error of IRF3-IFN immunity

J Exp Med (2025) 223 (1): e20250064.

https://doi.org/10.1084/jem.20250064

Published: 09 October 2025

View article titled, Role for NF-κB in herpes encephalitis pathology in mice genocopying an inborn error of IRF3-IFN immunity

Includes: Supplementary data

Journal Articles

Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2

J Exp Med (2025) 222 (12): e20251146.

https://doi.org/10.1084/jem.20251146

Published: 09 October 2025

View article titled, Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2

Includes: Supplementary data

Journal Articles

Human CD4⁺ T cells recognize Mycobacterium tuberculosis–infected macrophages amid broader responses

In Special Collection:

2025: The Year in Experimental Medicine

Volodymyr Stetsenko, Daniel P. Gail, Scott M. Reba, Vinicius G. Suzart, Robert Schauner, Avinaash K. Sandhu, Alessandro Sette, Mohammad Haj Dezfulian, Cecilia S. Lindestam Arlehamn, Stephen M. Carpenter

J Exp Med (2025) 222 (12): e20250460.

https://doi.org/10.1084/jem.20250460

Published: 24 September 2025

View article titled, Human CD4+ T cells recognize Mycobacterium tuberculosis–infected macrophages amid broader responses

Includes: Supplementary data

Journal Articles

Type I IFN drives neutrophil swarming, impeding lung T cell–macrophage interactions and TB control

William J. Branchett, Evangelos Stavropoulos, Jessica Shields, Alaa Al-Dibouni, Marcos Cardoso, Ana Isabel Fernandes, Lúcia Moreira-Teixeira, Hubert Slawinski, Anna Mikolajczak, Angela Rodgers, Margarida Saraiva, Anne O’Garra

J Exp Med (2025) 222 (12): e20250466.

https://doi.org/10.1084/jem.20250466

Published: 23 September 2025

View article titled, Type I IFN drives neutrophil swarming, impeding lung T cell–macrophage interactions and TB control

Includes: Supplementary data

Journal Articles

DUX4-stimulated genes define an antiviral defense program in human placental trophoblasts

In Special Collection:

Cytokines Collection 2025

Joshua Hatterschide, Liheng Yang, Carolyn B. Coyne

J Exp Med (2025) 222 (12): e20250448.

https://doi.org/10.1084/jem.20250448

Published: 18 September 2025

View article titled, DUX4-stimulated genes define an antiviral defense program in human placental trophoblasts

Includes: Supplementary data

Journal Articles

TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming

In Special Collection:

Cytokines Collection 2025 , Pattern Recognition Receptors and Beyond

Wenjie Zhu, Xiaoyan Xu, Vijayaraj Nagarajan, Jing Guo, Akriti Gupta, Zixuan Peng, Amy Zhang, Jie Liu, Mary J. Mattapallil, Yingyos Jittayasothorn, Reiko Horai, Yasmine Belkaid, Michael G. Constantinides, Anthony J. St Leger, Rachel R. Caspi

J Exp Med (2025) 222 (11): e20251046.

https://doi.org/10.1084/jem.20251046

Published: 11 September 2025

View article titled, TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming

Includes: Supplementary data

Journal Articles

Salmonella-superspreader hosts require gut regulatory T cells to maintain a disease-tolerant state

In Special Collection:

Cytokines Collection 2025

Blanda Di Luccia, Liliana M. Massis, Daniel S.C. Butler, Ramya Narasimhan, Sarah J. Ruddle, Trung H.M. Pham, José G. Vilches-Moure, Denise M. Monack

J Exp Med (2025) 222 (11): e20242431.

https://doi.org/10.1084/jem.20242431

Published: 09 September 2025

View article titled, Salmonella-superspreader hosts require gut regulatory T cells to maintain a disease-tolerant state

Includes: Supplementary data

Update search

NARROW

Format

Subjects

Journal

Article Type

Date

Single-cell and spatial profiling highlights TB-induced myofibroblasts as drivers of lung pathology

Transcription of HIV-1 is heterogenous among authentic latent CD4⁺ T cell clones

ERAdP facilitates biogenesis of dense core vesicles in Paneth cells to enhance intestinal defense

Antibiotic use in early life impairs MAIT cell–mediated immunity in adulthood

Does fever drive the evolution of antiviral genes?

Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis

Dynamics of natural and pharmacologic control of an SIV variant with an envelope trafficking defect

Autoantibodies neutralizing type I IFNs in a fatal case of H5N1 avian influenza

pDCs amplify tissue-resident memory CD8⁺ T cell responses during viral reinfection

SLC7A8 is essential for metabolic fitness and function of Th2 cells

Heterologous mucosal vaccine boosting enhances mucosal and systemic immunity by distinct mechanisms

Genetically heterozygous - transcriptionally homozygous IRF7 deficiency underlies herpesvirus CNS infections in humans

Lung tissue–resident memory T cells optimize protection by IL-10 regulation of innate immunity

Role for NF-κB in herpes encephalitis pathology in mice genocopying an inborn error of IRF3-IFN immunity

Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2

Human CD4⁺ T cells recognize Mycobacterium tuberculosis–infected macrophages amid broader responses

Type I IFN drives neutrophil swarming, impeding lung T cell–macrophage interactions and TB control

DUX4-stimulated genes define an antiviral defense program in human placental trophoblasts

TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming

Salmonella-superspreader hosts require gut regulatory T cells to maintain a disease-tolerant state

Email alerts

Update search

Email alerts

This Feature Is Available To Subscribers Only