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Journal Articles

Preclinical validation of a potent γ-secretase modulator for Alzheimer’s disease prevention

In Special Collection:
Neuroscience Collection 2021 , Neurodegenerative Diseases: Emerging Mechanisms and Therapeutic Opportunities
Kevin D. Rynearson, Moorthi Ponnusamy, Olga Prikhodko, Yuhuan Xie, Can Zhang, Phuong Nguyen, Brenda Hug, Mariko Sawa, Ann Becker, Brian Spencer, Jazmin Florio, Michael Mante, Bahar Salehi, Carlos Arias, Douglas Galasko, Brian P. Head, Graham Johnson, Jiunn H. Lin, Steven K. Duddy, Robert A. Rissman, William C. Mobley, Gopal Thinakaran, Rudolph E. Tanzi, Steven L. Wagner
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (4): e20202560.
https://doi.org/10.1084/jem.20202560
Published: 02 March 2021
View articletitled, Preclinical validation of a potent γ-secretase modulator for Alzheimer’s disease prevention
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Includes: Supplementary data
Journal Articles

A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment

In Special Collection:
Neuroscience Collection 2021
Alessia Balestrini, Victory Joseph, Michelle Dourado, Rebecca M. Reese, Shannon D. Shields, Lionel Rougé, Daniel D. Bravo, Tania Chernov-Rogan, Cary D. Austin, Huifen Chen, Lan Wang, Elisia Villemure, Daniel G.M. Shore, Vishal A. Verma, Baihua Hu, Yong Chen, Laurie Leong, Chris Bjornson, Kathy Hötzel, Alvin Gogineni, Wyne P. Lee, Eric Suto, Xiumin Wu, John Liu, Juan Zhang, Vineela Gandham, Jianyong Wang, Jian Payandeh, Claudio Ciferri, Alberto Estevez, Christopher P. Arthur, Jens Kortmann, Ryan L. Wong, Jose E. Heredia, Jonas Doerr, Min Jung, Jason A. Vander Heiden, Merone Roose-Girma, Lucinda Tam, Kai H. Barck, Richard A.D. Carano, Han Ting Ding, Bobby Brillantes, Christine Tam, Xiaoying Yang, Simon S. Gao, Justin Q. Ly, Liling Liu, Liuxi Chen, Bianca M. Liederer, Joseph H. Lin, Steven Magnuson, Jun Chen, David H. Hackos, Justin Elstrott, Alexis Rohou, Brian S. Safina, Matthew Volgraf, Rebecca N. Bauer, Lorena Riol-Blanco
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (4): e20201637.
https://doi.org/10.1084/jem.20201637
Published: 23 February 2021
View articletitled, A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment
Open the PDF for A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment in another window
Includes: Supplementary data
Journal Articles

Type 1 conventional dendritic cells are systemically dysregulated early in pancreatic carcinogenesis

In Special Collection:
JEM 2020 Update on Cancer Immunology and Immunotherapy
Jeffrey H. Lin, Austin P. Huffman, Max M. Wattenberg, David M. Walter, Erica L. Carpenter, David M. Feldser, Gregory L. Beatty, Emma E. Furth, Robert H. Vonderheide
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (8): e20190673.
https://doi.org/10.1084/jem.20190673
Published: 26 May 2020
View articletitled, Type 1 conventional dendritic cells are systemically dysregulated early in pancreatic carcinogenesis
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Includes: Supplementary data
Journal Articles

Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion.

H Lin, S F Bolling, P S Linsley, R Q Wei, D Gordon, C B Thompson, L A Turka
Journal: Journal of Experimental Medicine
J Exp Med (1993) 178 (5): 1801–1806.
https://doi.org/10.1084/jem.178.5.1801
Published: 01 November 1993
View articletitled, Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion.
Open the PDF for Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion. in another window
Journal Articles

Induction of autoreactive B cells allows priming of autoreactive T cells.

R H Lin, M J Mamula, J A Hardin, C A Janeway, Jr
Journal: Journal of Experimental Medicine
J Exp Med (1991) 173 (6): 1433–1439.
https://doi.org/10.1084/jem.173.6.1433
Published: 01 June 1991
View articletitled, Induction of autoreactive B cells allows priming of autoreactive T cells.
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