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Wyne P. Lee
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Journal Articles

A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment

In Special Collection:
Neuroscience Collection 2021
Alessia Balestrini, Victory Joseph, Michelle Dourado, Rebecca M. Reese, Shannon D. Shields, Lionel Rougé, Daniel D. Bravo, Tania Chernov-Rogan, Cary D. Austin, Huifen Chen, Lan Wang, Elisia Villemure, Daniel G.M. Shore, Vishal A. Verma, Baihua Hu, Yong Chen, Laurie Leong, Chris Bjornson, Kathy Hötzel, Alvin Gogineni, Wyne P. Lee, Eric Suto, Xiumin Wu, John Liu, Juan Zhang, Vineela Gandham, Jianyong Wang, Jian Payandeh, Claudio Ciferri, Alberto Estevez, Christopher P. Arthur, Jens Kortmann, Ryan L. Wong, Jose E. Heredia, Jonas Doerr, Min Jung, Jason A. Vander Heiden, Merone Roose-Girma, Lucinda Tam, Kai H. Barck, Richard A.D. Carano, Han Ting Ding, Bobby Brillantes, Christine Tam, Xiaoying Yang, Simon S. Gao, Justin Q. Ly, Liling Liu, Liuxi Chen, Bianca M. Liederer, Joseph H. Lin, Steven Magnuson, Jun Chen, David H. Hackos, Justin Elstrott, Alexis Rohou, Brian S. Safina, Matthew Volgraf, Rebecca N. Bauer, Lorena Riol-Blanco
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (4): e20201637.
https://doi.org/10.1084/jem.20201637
Published: 23 February 2021
View article titled, A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment
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Includes: Supplementary data
Journal Articles

Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation

In Special Collection:
Innate Immune Sensors in Health and Disease
Bettina L. Lee, Irma B. Stowe, Aaron Gupta, Opher S. Kornfeld, Merone Roose-Girma, Keith Anderson, Søren Warming, Juan Zhang, Wyne P. Lee, Nobuhiko Kayagaki
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (9): 2279–2288.
https://doi.org/10.1084/jem.20180589
Published: 22 August 2018
View article titled, Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation
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Includes: Supplementary data
Journal Articles

Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation

Michael C. Chang, Karpagam Srinivasan, Brad A. Friedman, Eric Suto, Zora Modrusan, Wyne P. Lee, Joshua S. Kaminker, David V. Hansen, Morgan Sheng
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (9): 2611–2628.
https://doi.org/10.1084/jem.20160999
Published: 04 August 2017
View article titled, Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation
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Includes: Supplementary data
Journal Articles

IL-33 amplifies an innate immune response in the degenerating retina

Hongkang Xi, Kenneth J. Katschke, Jr, Yun Li, Tom Truong, Wyne P. Lee, Lauri Diehl, Linda Rangell, Jianhua Tao, Rommel Arceo, Jeffrey Eastham-Anderson, Jason A. Hackney, Antonio Iglesias, Javier Cote-Sierra, Justin Elstrott, Robby M. Weimer, Menno van Lookeren Campagne
Journal: Journal of Experimental Medicine
J Exp Med (2016) 213 (2): 189–207.
https://doi.org/10.1084/jem.20150894
Published: 11 January 2016
View article titled, IL-33 amplifies an innate immune response in the degenerating retina
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Includes: Supplementary data
Journal Articles

Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling

Derek A. Holmes, Eric Suto, Wyne P. Lee, Qinglin Ou, Qian Gong, Hamish R.C. Smith, Patrick Caplazi, Andrew C. Chan
Journal: Journal of Experimental Medicine
J Exp Med (2015) 212 (7): 1081–1093.
https://doi.org/10.1084/jem.20142130
Published: 15 June 2015
View article titled, Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling
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Includes: Supplementary data
Journal Articles

A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis

Kenneth J. Katschke, Jr., Karim Y. Helmy, Micah Steffek, Hongkang Xi, JianPing Yin, Wyne P. Lee, Peter Gribling, Kai H. Barck, Richard A.D. Carano, Robin E. Taylor, Linda Rangell, Lauri Diehl, Philip E. Hass, Christian Wiesmann, Menno van Lookeren Campagne
Journal: Journal of Experimental Medicine
J Exp Med (2007) 204 (6): 1319–1325.
https://doi.org/10.1084/jem.20070432
Published: 04 June 2007
View article titled, A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis
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Includes: Supplementary data