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Issues

Volume 206, Issue 2
16 February 2009
Journal of Experimental Medicine Cover Image for Volume 206, Issue 2
All Issues
ISSN 0022-1007
EISSN 1540-9538

In This Issue

Life after shock
Amy Maxmen
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Toxo has a ticket to ride
Amy Maxmen
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Fine-tuning helper Ts
Amy Maxmen
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Virus-friendly Th17s
Amy Maxmen
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Bound to arthritis
Amy Maxmen
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People & Ideas

David Artis: Fear no worm
Amy Maxmen

As the incidence of inflammatory disease and food allergies increases in the industrialized world, David Artis wonders if something is wrong with the little friends in our guts.

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Commentary

New twist on the regulation of NKG2D ligand expression
Adelheid Cerwenka
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Rethinking T cell immunity in oropharyngeal candidiasis
Liise-anne Pirofski,Arturo Casadevall
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Brief Definitive Report

Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function
Christopher J. Haines,Thierry D. Giffon,Li-Sheng Lu,Xiaowei Lu,Marc Tessier-Lavigne,Douglas T. Ross,David B. Lewis
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Article

Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress
Timothy J. Nice,Laurent Coscoy,David H. Raulet
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Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis
Heather R. Conti,Fang Shen,Namrata Nayyar,Eileen Stocum,Jianing N. Sun,Matthew J. Lindemann,Allen W. Ho,Justine Hoda Hai,Jeffrey J. Yu,Ji Won Jung,Scott G. Filler,Patricia Masso-Welch,Mira Edgerton,Sarah L. Gaffen
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Th17 cells enhance viral persistence and inhibit T cell cytotoxicity in a model of chronic virus infection
Wanqiu Hou,Hyun Seok Kang,Byung S. Kim
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Down-regulation of Gfi-1 expression by TGF-β is important for differentiation of Th17 and CD103+ inducible regulatory T cells
Jinfang Zhu,Todd S. Davidson,Gang Wei,Dragana Jankovic,Kairong Cui,Dustin E. Schones,Liying Guo,Keji Zhao,Ethan M. Shevach,William E. Paul
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Contrasting roles for all-trans retinoic acid in TGF-β–mediated induction of Foxp3 and Il10 genes in developing regulatory T cells
Craig L. Maynard,Robin D. Hatton,Whitney S. Helms,James R. Oliver,Charles B. Stephensen,Casey T. Weaver
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Differential roles of migratory and resident DCs in T cell priming after mucosal or skin HSV-1 infection
Heung Kyu Lee,Melodie Zamora,Melissa M. Linehan,Norifumi Iijima,David Gonzalez,Ann Haberman,Akiko Iwasaki
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Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation
Muzlifah Haniffa,Florent Ginhoux,Xiao-Nong Wang,Venetia Bigley,Michal Abel,Ian Dimmick,Sarah Bullock,Marcos Grisotto,Trevor Booth,Peter Taub,Catharien Hilkens,Miriam Merad,Matthew Collin
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Antibody to the dendritic cell surface activation antigen CD83 prevents acute graft-versus-host disease
John Wilson,Hannah Cullup,Rohan Lourie,Yonghua Sheng,Anna Palkova,Kristen J. Radford,Anne M. Dickinson,Alison M. Rice,Derek N.J. Hart,David J. Munster
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Host ER–parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii–infected dendritic cells
Romina S. Goldszmid,Isabelle Coppens,Avital Lev,Pat Caspar,Ira Mellman,Alan Sher
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Anaphylactic shock depends on endothelial Gq/G11
Hanna Korhonen,Beate Fisslthaler,Alexandra Moers,Angela Wirth,Daniel Habermehl,Thomas Wieland,Günther Schütz,Nina Wettschureck,Ingrid Fleming,Stefan Offermanns
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CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance
Randall H. Friedline,David S. Brown,Hai Nguyen,Hardy Kornfeld,JinHee Lee,Yi Zhang,Mark Appleby,Sandy D. Der,Joonsoo Kang,Cynthia A. Chambers
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The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion
Catherine Haluszczak,Adovi D. Akue,Sara E. Hamilton,Lisa D.S. Johnson,Lindsey Pujanauski,Lenka Teodorovic,Stephen C. Jameson,Ross M. Kedl
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Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis
Hüseyin Uysal,Robert Bockermann,Kutty S. Nandakumar,Bettina Sehnert,Estelle Bajtner,Åke Engström,Guy Serre,Harald Burkhardt,Marjolein M.G.M. Thunnissen,Rikard Holmdahl
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Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain
Jürgen Kuball,Beate Hauptrock,Victoria Malina,Edite Antunes,Ralf-Holger Voss,Matthias Wolfl,Roland Strong,Matthias Theobald,Philip D. Greenberg
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Polζ ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability
Dominik Schenten,Sven Kracker,Gloria Esposito,Sonia Franco,Ulf Klein,Michael Murphy,Frederick W. Alt,Klaus Rajewsky
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